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Head & Neck Cancer Clinical Trials

Browse 313 head & neck cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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(89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma

for
Head and Neck Squamous Cell Carcinoma,
Location: Nashville TN
Sponsor: Eben Rosenthal

Sex: All

Age: 19+

Code: NCT05747625

Phase1, Recruiting

A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Response and Resistance in Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC)

for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT07408063

Phase2, Recruiting

5-Fluorouracil Response and Optimization STudy (The FROST Trial)

for
Squamous Cell Carcinoma of Head and Neck,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07419464

Phase2, Recruiting

Window of Opportunity in Preserving Laryngeal Function Trial

for
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M),
Location: Pittsburgh PA
Sponsor: Matthew Spector

Sex: All

Age: 18+

Code: NCT07423078

Phase2, Recruiting

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

for
Head and Neck Squamous Cell Carcinoma (HNSCC)
Location: Willow Grove PA, Richmond VA, Fairfax VA, Rochester NY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06769698

Phase2, Recruiting

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A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

for
Squamous Cell Carcinoma of Head and Neck
Location: Boston MA, The Bronx NY, Philadelphia PA,
Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All

Age: 18 - 70+

Code: NCT07219212

Phase1, Recruiting

A Study of the Use of 3D Technology to Guide Head and Neck Surgery

for
Surgery, Head and Neck Disorder
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06676592

Recruiting

High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors

for
Cranial Nerve Disorder, Head and Neck Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04151082

Phase1, Phase2, Recruiting

CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs

for
Head and Neck Squamous Cell Carcinoma,
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07172256

Phase2, Recruiting

Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas

for
Squamous Cell Carcinoma of Head and Neck
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT07455032

Phase1, Recruiting

Pembrolizumab + N-803 Alone or in Combination With PD-L1 t-haNK Cells for Resectable Head and Neck Squamous Cell Carcinoma

for
Stage II Squamous Cell Carcinoma of the Head and Neck,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06161545

Phase2, Recruiting

Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck

for
Cutaneous Squamous Cell Carcinoma of the Head and Neck,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06990737

Phase2, Recruiting

Neoadjuvant Ficerafusp Alfa With Pembrolizumab in Resectable SCC

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07465276

Phase2, Recruiting

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

for
Metastatic Head-and-neck Squamous-cell Carcinoma,
Location: South Portland ME, Boston MA, New Haven CT,
Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06064877

Phase3, Recruiting

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for
Solid Tumor, Melanoma, HNSCC, Sarcoma, Squamous Cell Carcinoma,
Location: Boston MA, Fairfax VA, Pittsburgh PA, Dallas TX
Sponsor: ImmVira Pharma Co. Ltd

Sex: All

Age: 18+

Code: NCT04370587

Phase1, Phase2, Recruiting

A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors

for
Solid Tumor, HNSCC, RCC, CRC
Location: Jacksonville FL, Rochester MN, Scottsdale AZ,
Sponsor: SparX Biotech(Jiangsu) Co., Ltd.

Sex: All

Age: 18+

Code: NCT06259552

Phase1, Recruiting

Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study.

for
Head and Neck Squamous Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06162377

Recruiting

ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

for
Advanced Solid Tumor, PDAC, HNSCC
Location: Boston MA, New Haven CT, New York NY, St Louis MO,
Sponsor: Adcendo ApS

Sex: All

Age: 18+

Code: NCT06597721

Phase1, Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for
Cervical Cancer,
Location: Hackensack NJ, Montreal, Hamilton, Nashville TN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT04895709

Phase1, Phase2, Recruiting

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

for
Squamous Non-small-cell Lung Cancer,
Location: New Haven CT, Hackensack NJ, Fairfax VA, Louisville KY,
Sponsor: Alentis Therapeutics AG

Sex: All

Age: 18+

Code: NCT06747585

Phase1, Phase2, Recruiting