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Oncology Clinical Trials

Browse 9,232 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas

for
Soft Tissue Sarcomas
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT04506008

Phase2, Recruiting

A Couple-based HIV Prevention Intervention to Promote HIV Protection Among Latino Male Couples

for
HIV/AIDS
Location: Philadelphia PA
Sponsor: Temple University

Sex: Male

Age: 18+

Code: NCT03048838

Recruiting

Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer

for
Ovary Cancer, Fallopian Tube Cancer,
Location: Philadelphia PA, Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female

Age: 18+

Code: NCT06617923

Phase2, Recruiting

Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities

for
Colorectal Carcinoma
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 45+

Code: NCT05447923

Recruiting

Bispecific Antibody in Finding Tumor Cells in Patients With Colorectal Cancer

for
Colorectal Cancer
Location: Washington DC
Sponsor: Garden State Cancer Center at the Center for Molecular Medicine and Immunology

Sex: All

Age: 18+

Code: NCT00895323

Phase1, Recruiting

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Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

for
Rectal Cancer
Location: Boston MA, St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT03516708

Phase1, Phase2, Recruiting
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A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

for
Primary Open Angle Glaucoma
Location: Philadelphia PA, Bala-Cynwyd PA, Charlottesville VA,
Sponsor: AbbVie

Sex: All

Age: 45+

Code: NCT06822738

Phase3, Recruiting

Pembrolizumab in Treating Participants With Leukoplakia

for
Erythroleukoplakia, Leukoplakia, Verrucous Oral Leukoplakia
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT03603223

Phase2, Recruiting

Social Relationships and Accelerated Aging in Hematopoietic Cell Transplant Survivors

for
Hematopoietic and Lymphoid Cell Neoplasm
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT04892823

Recruiting

18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy

for
Complex Atypical Hyperplasia, Endometrial Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: Female

Age: 18+

Code: NCT05483023

Phase2, Recruiting

Tislelizumab in People With Colorectal Cancer

for
Colorectal Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06529523

Phase2, Recruiting

Geriatric Assessment and Technology Evaluation in Prostate Cancer

for
Prostate Cancer, Prostate Cancer Metastatic
Location: Chicago IL
Sponsor: University of Chicago

Sex: Male

Age: 0+

Code: NCT06215508

Recruiting

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

for
Solid Tumor, Lymphoma
Location: Morristown NJ, Chicago IL
Sponsor: MultiVir, Inc.

Sex: All

Age: 18+

Code: NCT03544723

Phase2, Recruiting

GM-CSF With Post-Transplant Cyclophosphamide

for
Transplant-Related Hematologic Malignancy
Location: Atlanta GA
Sponsor: Northside Hospital, Inc.

Sex: All

Age: 18 - 70+

Code: NCT04237623

Phase2, Recruiting

A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849

for
Advanced Solid Tumor
Location: Fairfax VA, Cleveland OH, Dallas TX, San Antonio TX,
Sponsor: 1ST Biotherapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05761223

Phase1, Phase2, Recruiting

Time Restricted Eating for the Improvement of Outcomes in Patients With Stage I-III Breast Cancer Receiving Chemotherapy Before Surgery

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Philadelphia PA, Cherry Hill NJ, Sewell NJ,
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT05327608

Recruiting

A Study of ZEN003694 in People With Squamous Cell Lung Cancer

for
Squamous Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05607108

Phase2, Recruiting

A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

for
Endometrioid Cancer, Mucinous Ovarian Cancer,
Location: Orlando FL, New Orleans LA, Oklahoma City OK,
Sponsor: University of Oklahoma

Sex: Female

Age: 18 - 70+

Code: NCT05512208

Phase2, Recruiting

Dose-Dense Chemotherapy Plus Bevacizumab in High Risk Lymph Node Positive Breast Cancer: A Pilot Study

for
Breast Cancer
Location: Santa Monica CA
Sponsor: Chap, Linnea I., M.D.

Sex: Female

Age: 18+

Code: NCT00378638

Phase2, Recruiting

Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer

for
Breast Cancer, Locally Advanced Breast Cancer,
Location: Stony Brook NY
Sponsor: Alison Stopeck

Sex: Female

Age: 18+

Code: NCT06220214

Early_phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer