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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Dose Study of Doxil in a Dose Dense, 14 Day CDOP/Rituximab Regimen for Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma (NHL)> 60 Years or With Compromised Cardiac Status.

for
Diffuse Large B Cell Lymphoma, Lymphoma, Non-Hodgkin
Location: Baltimore MD, Randallstown MD
Sponsor: The Alvin and Lois Lapidus Cancer Institute

Sex: All

Age: 18+

Code: NCT00333008

Phase2, Recruiting

Communication Issues in Patient and Provider Discussions of Immunotherapy

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Decatur GA, Atlanta GA
Sponsor: Emory University

Sex: All

Age: 0+

Code: NCT05873608

Recruiting

Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer

for
Head and Neck Cancer
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT00230308

Recruiting

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

for
HPV-Associated Oropharyngeal Squamous Cell Carcinoma,
Location: Boston MA
Sponsor: Jonathan Schoenfeld, MD, MPH

Sex: All

Age: 22+

Code: NCT04900623

Phase2, Recruiting

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

for
Hematologic Neoplasms
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12 - 70+

Code: NCT05327023

Phase1, Phase2, Recruiting

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Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias

for
Leukemia, Lymphocytic, Chronic, B-Cell,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06364423

Phase1, Phase2, Recruiting

Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas

for
Metastatic Cancer
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06389123

Phase1, Recruiting

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, Farmington CT, New Haven CT, New York NY,
Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All

Age: 18+

Code: NCT06667908

Phase2, Recruiting

Weighted Blanket Use to Reduce Anxiety in Oncology Patients

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06089408

Recruiting

Efficacy and Safety Study of Niraparib in Melanoma With Genetic Homologous Recombination (HR) Mutation

for
Metastatic Melanoma
Location: San Francisco CA
Sponsor: California Pacific Medical Center Research Institute

Sex: All

Age: 18+

Code: NCT03925350

Phase2, Recruiting

Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal)

for
Head and Neck Carcinoma, Localized Head and Neck Carcinoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06572423

Recruiting

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for
Differentiated Thyroid Cancer, Pediatric Cancer, Cancer,
Location: Philadelphia PA, Memphis TN, Houston TX, Seattle WA,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 2 - 70+

Code: NCT05783323

Phase2, Recruiting

Cryoablation+Ipilimumab+Nivolumab in Melanoma

for
Metastatic Melanoma, Skin Cancer
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05779423

Phase2, Recruiting

Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy

for
Chemotherapy-Induced Peripheral Neuropathy,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05411523

Recruiting

Study of NMS-03597812 in Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
Relapsed/Refractory Acute Myeloid Leukemia
Location: Newark DE, Canton OH, Atlanta GA, Houston TX, Aurora CO,
Sponsor: Nerviano Medical Sciences

Sex: All

Age: 18+

Code: NCT06549790

Phase1, Recruiting

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors

for
Medulloblastoma Recurrent, Ependymoma Recurrent, ATRT Recurrent,
Location: Grand Rapids MI, Austin TX
Sponsor: Medical University of Vienna

Sex: All

Age: 0 - 19

Code: NCT01356290

Phase2, Recruiting

A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer

for
Breast Cancer
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT06327490

Phase2, Recruiting

Naltrexone and Propranolol Combined With Immunotherapy

for
Advanced Melanoma
Location: New Brunswick NJ
Sponsor: Sarah Weiss

Sex: All

Age: 18+

Code: NCT05968690

Phase1, Recruiting

The Vitality Project for Fatigued Female Cancer Survivors

for
Fatigue, Cancer Survivorship
Location: Providence RI
Sponsor: The Miriam Hospital

Sex: Female

Age: 18 - 70

Code: NCT03259438

Recruiting

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

for
Clonal Cytopenia of Undetermined Significance,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03418038

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer