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Oncology Clinical Trials

Browse 9,250 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

for
Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma,
Location: Boston MA, Hackensack NJ, Buffalo NY, Pittsburgh PA,
Sponsor: Regeneron Pharmaceuticals

Sex: Female

Age: 18+

Code: NCT06469281

Phase 1, Recruiting

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

for
B-Cell Leukemia, Non-Hodgkin's Lymphoma,
Location: Ottawa, Toronto, Calgary, Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 1+

Code: NCT06208735

Phase 1, Recruiting

Patient-Specific Computational Walking Models in Improving Surgical and Rehabilitation Treatment in Patients With Pelvic Sarcomas

for
Pelvic Sarcoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05054335

Recruiting

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

for
Metastatic Disease, Primary Tumor, Solid Malignancies
Location: Cincinnati OH
Sponsor: Roshni Dasgupta

Sex: All

Age: 0 - 45

Code: NCT04492735

Recruiting

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

for
Malignant Peritoneal Mesothelioma, Peritoneal Mesothelioma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06057935

Phase 2, Recruiting

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Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

for
Prostate Cancer, Magnetic Resonance Imaging, Population at Risk
Location: Lake Success NY
Sponsor: Northwell Health

Sex: Male

Age: 40 - 55

Code: NCT05384535

Recruiting

Molecular Genetics Studies of Cancer Patients and Their Relatives

for
Malignant Neoplasm
Location: Brighton MA, Mount Kisco NY, Poughkeepsie NY,
Sponsor: City of Hope Medical Center

Sex: All

Age: 0+

Code: NCT04185935

Recruiting

Sustaining Physical Activity After Cancer Exercise Sessions

for
Exercise Oncology, Physical Activity Behavior,
Location: Aurora CO
Sponsor: Colorado State University

Sex: All

Age: 18+

Code: NCT06359210

Recruiting

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for
Low Grade Serous Ovarian Cancer
Location: New Haven CT, New York NY, Montreal, Philadelphia PA,
Sponsor: Verastem, Inc.

Sex: Female

Age: 18+

Code: NCT06072781

Phase 3, Recruiting

Propranolol With Chemotherapy or Chemoradiation for Esophageal Adenocarcinoma

for
Esophageal Adenocarcinoma
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT04682158

Phase 2, Recruiting

Food and Microbiome Longitudinal Investigation (FAMiLI)

for
Cancer, Cardiovascular Diseases
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 40+

Code: NCT03293758

Recruiting

International PPB/DICER1 Registry

for
Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor,
Location: Minneapolis MN
Sponsor: Children's Hospitals and Clinics of Minnesota

Sex: All

Age: 0 - 70+

Code: NCT03382158

Recruiting

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

for
Ependymoma, Medulloblastoma, Glioblastoma, Primary Brain Tumor
Location: Augusta GA
Sponsor: Theodore S. Johnson

Sex: All

Age: 3 - 25

Code: NCT05106296

Phase 1, Recruiting

An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, New York NY, Philadelphia PA, Fairfax VA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06589596

Phase 1, Recruiting

Biomarkers for Risk Stratification in Lung Cancer

for
Nodule Solitary Pulmonary, Non-small Cell Lung Cancer
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 40+

Code: NCT03774758

Recruiting

Stage II/III Colorectal Cancer Recurrence

for
Colorectal Cancer, Colorectal Adenocarcinoma,
Location: Monrovia CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06314958

Recruiting

Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: Fairway KS
Sponsor: Celyad Oncology SA

Sex: All

Age: 18+

Code: NCT04167696

Phase 1, Recruiting

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

for
Ankylosing Spondylitis, Autoimmune Disease, Crohn Disease,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04751396

Recruiting

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06662058

Recruiting

Diphencyprone Plus Immune Checkpoint Inhibition in the Treatment of Cutaneous Metastases

for
Cutaneous Metastases
Location: New York NY
Sponsor: Nicholas Gulati

Sex: All

Age: 18+

Code: NCT05481658

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer