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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas

for
Soft Tissue Sarcoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06500065

Recruiting

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

for
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: Charlotte NC, Memphis TN, Tulsa OK
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06533748

Phase 2, Recruiting

Brain Slice Explants to Predict Drug Response in Brain Tumors

for
Central Nervous System Tumor
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 0+

Code: NCT05978557

Recruiting

Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position

for
Breast Cancer, Radiation Dermatitis
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06915857

Phase 3, Recruiting

Ph I/II Trial of Cord Blood-derived NK Cells With NY-ESO-1 TCR/IL-15 for R/R Myeloma

for
Relapsed/Refractory Myeloma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT06066359

Phase 1, Phase 2, Recruiting

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Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects

for
Non Small Cell Lung Cancer
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06221800

Recruiting

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

for
Colonic Neoplasms, Neoplasms, Colon
Location: Halifax, New York NY, New Haven CT, The Bronx NY,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT05855200

Phase 3, Recruiting

Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for
Grade 3b Follicular Lymphoma, High Grade B-Cell Lymphoma,
Location: New York NY, Richmond VA, Webster NY, Rochester NY,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05890352

Phase 2, Recruiting

Investigations of Reproductive Cancers in Women

for
Uterine Cancer
Location: New York NY, Orlando FL, Akron OH, Columbus OH,
Sponsor: PinkDx, Inc.

Sex: Female

Age: 45 - 70+

Code: NCT06527157

Recruiting

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for
Endometrial Cancer
Location: Oklahoma City OK
Sponsor: Alliance Foundation Trials, LLC.

Sex: Female

Age: 18+

Code: NCT04486352

Phase 1, Phase 2, Recruiting

Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Columbus OH
Sponsor: Margaret Gatti-Mays

Sex: All

Age: 18+

Code: NCT06026657

Phase 1, Phase 2, Recruiting

PSMA PET Response Guided SabR in High Risk Pca

for
Prostate Adenocarcinoma
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: Male

Age: 18 - 70+

Code: NCT06044857

Phase 1, Recruiting

Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders

for
Islet Cell Tumor, Pancreatic Cancer, Pancreatic Disease,
Location: Jacksonville FL, Rochester MN, Phoenix AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT00830557

Recruiting

Cognitive Status After Removal of Skull Base Meningioma

for
Meningioma, Skull Base Meningioma, Frontal Meningioma,
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 18 - 70+

Code: NCT04635657

Recruiting

Impact of Intraoperative ICG on Functional Outc in RARP

for
Prostate Adenocarcinoma
Location: Orange CA
Sponsor: University of California, Irvine

Sex: Male

Age: 18+

Code: NCT06446648

Early Phase 1, Recruiting

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS

for
Whole Genome Sequencing, Acute Myeloid Leukemia,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT04986657

Recruiting

Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr

for
Prostate Cancer
Location: New York NY, Cleveland OH
Sponsor: Weill Medical College of Cornell University

Sex: Male

Age: 18+

Code: NCT05948657

Recruiting

PRO and Wearable Data Insights From Individuals With R/R Multiple Myeloma

for
Multiple Myeloma, Relapsed Hematologic Malignancy
Location: Seattle WA
Sponsor: Pack Health

Sex: All

Age: 18+

Code: NCT05956457

Recruiting

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors

for
Kidney Cancer
Location: Richmond VA, San Diego CA, Los Angeles CA
Sponsor: Azienda Ospedaliero-Universitaria Careggi

Sex: All

Age: 18+

Code: NCT05363657

Recruiting

Alternate Day Fasting After Surgery for Patients Undergoing Chemotherapy

for
Ovary Cancer, Endometrial Cancer, Uterine Cancer
Location: Chicago IL
Sponsor: Northwestern University

Sex: Female

Age: 18+

Code: NCT05990426

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer