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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)

for
Cancer Survivors
Location: Detroit MI
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 18+

Code: NCT03750981

Recruiting

Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases

for
Colorectal Cancer Metastatic
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT05248581

Recruiting

Real World Evidence on the Use of Medical Cannabis in Pediatrics

for
Cancer, Epilepsy, Neurodevelopmental Disorders
Location: Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 3 - 17

Code: NCT05863910

Recruiting

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for
Locally Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Scarborough ME, Boston MA, Montreal, Philadelphia PA,
Sponsor: Turning Point Therapeutics, Inc.

Sex: All

Age: 0 - 25

Code: NCT04094610

Phase1, Phase2, Recruiting

Remote Monitoring With Health-Coaching to Improve Quality of Life in Older Patients With Multiple Myeloma

for
Multiple Myeloma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 65+

Code: NCT06145581

Recruiting

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A Study Comparing Quality of Life in Patients With Lymphedema Who Undergo Surgical Treatment Versus Non-Surgical Management

for
Lymphedema
Location: Rockville Centre NY, Harrison NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03248310

Recruiting

Observing People With Desmoid-Type Fibromatosis

for
Desmoid Fibromatosis
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04281381

Recruiting

Radiologic Pathologic Correlation of Imaging to Distinguish True Progression From Pseudoprogression in Brain Malignancies

for
Brain Malignancies, Pseudoprogression
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06199479

Phase1, Recruiting

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

for
T-cell Acute Lymphoblastic Lymphoma, T-non-Hodgkin Lymphoma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 70+

Code: NCT03081910

Phase1, Recruiting

DCE-MRI Guided Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer

for
Borderline-resectable Pancreatic Cancer
Location: Columbus OH, Indianapolis IN
Sponsor: Ohio State University

Sex: All

Age: 19+

Code: NCT06173310

Recruiting

Selumetinib and Azacitidine in High Risk Chronic Blood Cancers

for
Chronic Myeloid Leukemia, Myelofibroses
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT03326310

Phase1, Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 16+

Code: NCT05269381

Phase1, Phase2, Recruiting

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

for
Multiple Myeloma
Location: Boston MA, The Bronx NY, New York NY, Hackensack NJ,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05201781

Recruiting

Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer

for
Oligometastatic Prostate Carcinoma, Prostate Adenocarcinoma
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06369610

Phase2, Recruiting

A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer

for
Endometrial Cancer, Stage III Endometrial Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT05691010

Early_phase1, Recruiting

Gut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming

for
Breast Cancer, Early-stage Breast Cancer
Location: Washington D.C. DC
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female

Age: 18+

Code: NCT06536881

Recruiting

Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism

for
Hyperparathyroidism, Primary
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT06562881

Recruiting

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

for
Breast Cancer, Lung Cancer, Multiple Myeloma, Ovarian Cancer,
Location: Canton OH, Massillon OH, Cleveland OH, Evanston IL
Sponsor: Carevive Systems, Inc.

Sex: All

Age: 18+

Code: NCT05974150

Recruiting

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

for
Metastatic Castration-Resistant Prostate Cancer
Location: Halifax, Chicoutimi, The Bronx NY, Montreal,
Sponsor: Pfizer

Sex: Male

Age: 18+

Code: NCT06629779

Phase3, Recruiting

Estradiol Plus Olaparib for Breast Cancer (PHOEBE)

for
Metastatic Breast Cancer
Location: Lebanon NH
Sponsor: Mary D Chamberlin

Sex: Female

Age: 18+

Code: NCT05900895

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer