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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Study of D3L-001 as Monotherapy in Subjects With HER2-Positive Advanced Solid Tumors

for
HER-2 Positive Advanced Solid Tumors
Location: New York NY
Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All

Age: 18+

Code: NCT05957536

Phase1, Recruiting

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

for
Bone Sarcoma, Osteosarcoma, Chondrosarcoma, Ewing's Sarcoma,
Location: Uniondale NY, Harrison NY, New York NY, Middletown NJ,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 4+

Code: NCT03442465

Recruiting

Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

for
PSMA PET-Positive Castration-Resistant Prostate Cancer
Location: Boston MA, New York NY, Durham NC, Cleveland OH,
Sponsor: Convergent Therapeutics

Sex: Male

Age: 18+

Code: NCT06549465

Phase2, Recruiting

Evaluation of IRDye800CW-nimotuzumab in Lung Cancer Surgery

for
Lung Cancer
Location: Saskatoon
Sponsor: University of Saskatchewan

Sex: All

Age: 18 - 70+

Code: NCT04459065

Phase1, Phase2, Recruiting

Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

for
Pancreatic Adenocarcinoma
Location: Louisville KY
Sponsor: University of Louisville

Sex: All

Age: 18+

Code: NCT03080974

Phase2, Recruiting

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Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies

for
Advanced Solid Malignancies
Location: New Brunswick NJ, Richmond VA, Sarasota FL,
Sponsor: Georgiamune Inc

Sex: All

Age: 18+

Code: NCT06028074

Phase1, Phase2, Recruiting

Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation Program

for
Pancreatic Cancer, Liver Cancer, Bile Duct Cancer,
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18 - 70+

Code: NCT03475966

Recruiting

Single Pre-Operative Radiation Therapy - With Delayed or No Surgery (SPORT-DNS)

for
Breast Cancer
Location: Montreal
Sponsor: Maisonneuve-Rosemont Hospital

Sex: Female

Age: 50+

Code: NCT05217966

Recruiting

Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples

for
Papillary Thyroid Cancer
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT06133374

Recruiting

Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA

for
Hip Dysplasia, Femoroacetabular Impingement, Osteoarthritis
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT04080466

Phase2, Recruiting

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

for
Metastatic Malignant Neoplasm
Location: West Islip NY, East Hills NY, Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT04068649

Phase2, Recruiting

IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures

for
Cancer Metastatic, Trauma, Pathologic Fracture
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 21+

Code: NCT04842266

Recruiting

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

for
Prostate Cancer
Location: Boston MA, Ottawa, Toronto, London, Ann Arbor MI,
Sponsor: University of British Columbia

Sex: Male

Age: 18+

Code: NCT04812366

Phase2, Recruiting

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

for
Head and Neck Squamous Cell Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06597565

Phase2, Recruiting

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

for
Colorectal Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT06205836

Phase2, Recruiting

Strategic Targeting for Optimal Prevention of Cancer

for
Early Detection of Cancer
Location: Prosper TX
Sponsor: ClinLogic LLC

Sex: All

Age: 65+

Code: NCT03897374

Recruiting

Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients

for
Multiple Endocrine Neoplasia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT03048266

Recruiting

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

for
NSCLC (Non-small Cell Lung Cancer), Solid Tumor
Location: Fairfax VA
Sponsor: Yuhan Corporation

Sex: All

Age: 18+

Code: NCT06616766

Phase1, Phase2, Recruiting

A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors

for
Solid Tumor
Location: Boston MA, Fairfax VA, Grand Rapids MI, San Antonio TX,
Sponsor: PAQ Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06797336

Phase1, Recruiting

68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas

for
Soft Tissue Sarcoma
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06500065

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer