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Oncology Clinical Trials

Browse 9,272 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Assessment of Cardiotoxicity by Cardiac Magnetic Resonance (CMR) in Breast Cancer Patients Receiving Trastuzumab

for
Stage I-IV Breast Cancer (Neo-adjuvant, Adjuvant, Locally Advanced and Metastatic),
Location: Toronto
Sponsor: Unity Health Toronto

Sex: All

Age: 18+

Code: NCT01022086

Recruiting

HIFU for Focal Ablation of Prostate Tissue: An Observational Study

for
Prostate Cancer
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Male

Age: 40 - 70+

Code: NCT03620786

Recruiting

Clinical Trial of PM54 in Advanced Solid Tumors Patients.

for
Advanced Solid Tumor
Location: San Antonio TX
Sponsor: PharmaMar

Sex: All

Age: 18+

Code: NCT05841563

Phase 1, Recruiting

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

for
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18 - 70+

Code: NCT01890486

Recruiting

Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

for
Lung Carcinoma, Lung Non-Small Cell Carcinoma,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT05802186

Recruiting

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Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases

for
Metastatic Malignant Neoplasm in the Brain,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06328686

Early Phase 1, Recruiting

Molecular and Genomic Profiling of Head and Neck Tumors

for
Head and Neck Neoplasms
Location: The Bronx NY
Sponsor: Montefiore Medical Center

Sex: All

Age: 0+

Code: NCT00200486

Recruiting

Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

for
Graft vs Host Disease
Location: Bethesda MD, Miami FL
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05531786

Phase 1, Phase 2, Recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: Male

Age: 18+

Code: NCT06236139

Phase 1, Phase 2, Recruiting

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

for
Urinary Bladder Neoplasms, Neoplasm Metastasis,
Location: Boston MA, The Bronx NY, New York NY, Burlington VT,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT05614739

Phase 1, Recruiting

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

for
Locally Advanced Intrahepatic Cholangiocarcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06058663

Phase 1, Recruiting

Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI

for
Acneiform Eruptions, Cancer, Treatment-Related
Location: Montreal
Sponsor: Lady Davis Institute

Sex: All

Age: 18+

Code: NCT04864717

Recruiting

Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors

for
Stage III Melanoma, Stage IV Melanoma
Location: Denver CO, Los Angeles CA
Sponsor: Taiga Biotechnologies, Inc.

Sex: All

Age: 18+

Code: NCT03385486

Phase 1, Recruiting

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC),
Location: Pittsburgh PA
Sponsor: Dan Zandberg

Sex: All

Age: 18+

Code: NCT06052839

Phase 2, Recruiting

Barrett's Esophagus Related Neoplasia (BERN) Project

for
Barrett's Esophagus, Neoplasms, Gastroesophageal Reflux
Location: Kansas City MO
Sponsor: Midwest Biomedical Research Foundation

Sex: All

Age: 18+

Code: NCT00590239

Recruiting

HIV Antiretroviral Drugs and Metabolism

for
HIV Infections
Location: San Francisco CA
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All

Age: 18+

Code: NCT00525239

Recruiting

Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant

for
Hematopoietic and Lymphoid System Neoplasm
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 70

Code: NCT04022239

Phase 1, Phase 2, Recruiting

A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer

for
Cancer Risk
Location: Aurora CO, Fort Collins CO, Colorado Springs CO,
Sponsor: University of Colorado, Denver

Sex: All

Age: 18+

Code: NCT03617939

Recruiting

Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

for
Lung Cancer, Nonsmall Cell
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT04691817

Phase 1, Phase 2, Recruiting

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

for
Advanced Malignant Solid Neoplasm,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT04511039

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer