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Oncology Clinical Trials

Browse 9,272 oncology clinical trials enrolling across the United States and Canada. 215 people applied to oncology studies last month. Search by city or state to find one near you.

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Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

for
Multiple Myeloma, Lymphoma, Non-Hodgkin,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02682667

Recruiting

A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

for
Solid Malignancies, Hematologic Malignancies
Location: Providence RI, New Haven CT, Charlottesville VA,
Sponsor: Immunome, Inc.

Sex: All

Age: 18+

Code: NCT06823167

Phase 1, Recruiting

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

for
Prostatic Neoplasms, Prostate Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: Male

Age: 18 - 70+

Code: NCT01834001

Recruiting

Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling

for
Dementia, Alzheimer Disease, Dementia With Lewy Bodies,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 30 - 70+

Code: NCT06529744

Recruiting

Study of SGR-3515 In Participants With Advanced Solid Tumors.

for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Fairfax VA, Toronto,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT06463340

Phase 1, Recruiting

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for
Colorectal Carcinoma, Endometrial Carcinoma, Melanoma,
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 30

Code: NCT04851119

Phase 1, Phase 2, Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor

for
Neoplasms, Tenosynovial Giant Cell Tumor
Location: Beverly Hills CA
Sponsor: Abbisko Therapeutics Co, Ltd

Sex: All

Age: 18+

Code: NCT04192344

Phase 1, Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

for
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer,
Location: Boston MA, Montreal, Toronto, Jacksonville FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06562192

Phase 1, Recruiting

Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

for
Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02754544

Recruiting

Embryonal Tumor With Multilayered Rosettes

for
Embryonal Tumor With Multilayered Rosettes,
Location: Hackensack NJ, Baltimore MD, Indianapolis IN,
Sponsor: University of California, San Francisco

Sex: All

Age: 0+

Code: NCT06861244

Phase 2, Recruiting

Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

for
Breast Cancer
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: Female

Age: 18+

Code: NCT06361940

Phase 2, Recruiting

Dual Perfusion Imaging for Characterizing Vascular Architecture of Brain Lesions

for
Brain Tumor, Brain Metastases
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05358340

Recruiting

Viscoelasticity Imaging to Assess Liver Cancer

for
Liver Cancer
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT04409340

Recruiting

Physician Perceptions About Parenteral Hydration in Latin America and Spain

for
Dehydration, Advanced Cancers
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT01011140

Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung,
Location: Boston MA, Montreal, Baltimore MD, Ottawa, Toronto,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT06131840

Phase 1, Recruiting

Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

for
Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC),
Location: Morristown NJ, Tyler TX, Houston TX, Dallas TX,
Sponsor: Stingray Therapeutics

Sex: All

Age: 18+

Code: NCT06589440

Phase 2, Recruiting

CD4CAR for CD4+ Leukemia and Lymphoma

for
T-cell Lymphoma, T-cell Leukemia
Location: New York NY, Miami FL, Indianapolis IN, Houston TX
Sponsor: Huda Salman

Sex: All

Age: 12+

Code: NCT03829540

Phase 1, Recruiting

pBI-11 & TA-HPV (With Pembrolizumab as Treatment for Patients w/Advanced, PD-L1 CPS≥1, hrHPV+ Oropharyngeal Cancer

for
Metastatic Oropharyngeal Carcinoma,
Location: Birmingham AL, Nashville TN
Sponsor: Michael K. Gibson

Sex: All

Age: 18+

Code: NCT05799144

Phase 2, Recruiting

[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application

for
Metastatic Castration-resistant Prostate Cancer
Location: Gettysburg PA, Los Angeles CA
Sponsor: FutureChem

Sex: Male

Age: 18+

Code: NCT05458544

Phase 1, Phase 2, Recruiting

Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for
Muscle Invasive Bladder Urothelial Carcinoma
Location: New York NY, Philadelphia PA, Indianapolis IN,
Sponsor: Matthew Galsky

Sex: All

Age: 18+

Code: NCT06809140

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer