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Oncology Clinical Trials

Browse 9,272 oncology clinical trials enrolling across the United States and Canada. 215 people applied to oncology studies last month. Search by city or state to find one near you.

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A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

for
Metastatic HER2-positive Breast Cancer
Location: Boston MA, Providence RI, Quebec, Long Island City NY,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06435429

Phase 3, Recruiting

Cell Saver Use in Bilateral Total Hip Arthroplasty (THA)

for
One-stage Bilateral Total Hip Replacement
Location: Philadelphia PA
Sponsor: Rothman Institute Orthopaedics

Sex: All

Age: 21+

Code: NCT01468129

Recruiting

Postop Pain Management in Pituitary Tumour Patients

for
Pituitary, Pain, Postoperative
Location: Hamilton
Sponsor: Hamilton Health Sciences Corporation

Sex: All

Age: 18 - 70+

Code: NCT06353529

Recruiting

MyVHL: Patient Natural History Study

for
Von Hippel-Lindau Disease,
Location: Boston MA
Sponsor: Joshua Mann, MPH

Sex: All

Age: 0+

Code: NCT03749980

Recruiting

Feasibility of FMISO in Brain Tumors

for
IDH Wild Type Glioblastoma
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT03649880

Phase 2, Recruiting

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Study of the Effect of Innate on the Inflammatory Response to Endotoxin

for
Asthma, Atherosclerosis, Metabolic Syndrome, Insulin Resistance,
Location: Research Triangle Park NC
Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All

Age: 18 - 70+

Code: NCT01143480

Recruiting

Early Detection of Endometrial/Ovarian Cancer and Hereditary Predisposition of These Cancers

for
Diagnoses Disease
Location: Montreal
Sponsor: McGill University

Sex: Female

Age: 45 - 70+

Code: NCT04891029

Recruiting

UNC Pleural Fluid Registry

for
Lung Cancer, Lung Infection, Breast Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05620329

Recruiting

Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System

for
Chronic Heart Failure, CKD Stage 3
Location: New York NY, Rochester NY, Greensboro NC, Asheville NC,
Sponsor: AquaPass Medical Ltd.

Sex: All

Age: 21 - 70+

Code: NCT06360380

Recruiting

A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.

for
Solid Tumor, Adult, Healthy Donors, COVID-19 Donors
Location: Huntersville NC
Sponsor: BioCytics, Inc.

Sex: All

Age: 5+

Code: NCT00571389

Recruiting

Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

for
Pituitary Neoplasm
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 18 - 70+

Code: NCT03678389

Recruiting

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

for
Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors,
Location: Washington D.C. DC, Durham NC, Cincinnati OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 1 - 70+

Code: NCT05868629

Recruiting

Model to Predict pCR and IrAEs in Early Stage Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer Stage IB (Resectable),
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT06250829

Recruiting

Lynch Syndrome X-Talk of Enteral Mucosa With Immune System

for
Lynch Syndrome, Lynch Syndrome I, Lynch Syndrome II,
Location: Monrovia CA
Sponsor: San Raffaele University

Sex: All

Age: 18+

Code: NCT06708429

Recruiting

Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1

for
Mesothelioma, Families
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2 - 70+

Code: NCT03830229

Recruiting

Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer

for
Prostate Cancer, Refractory Cancer,
Location: Winston-Salem NC, Salisbury NC
Sponsor: Wake Forest University Health Sciences

Sex: Male

Age: 18+

Code: NCT04337580

Phase 2, Recruiting

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

for
Lung Cancer, EGFR Gene Mutation
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 40 - 70+

Code: NCT06716580

Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for
Non-small Cell Lung Cancer
Location: Halifax, Stamford CT, Trois-Rivieres, Albany NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06345729

Phase 3, Recruiting

Specimen Collection From Patients With Non-Hematologic Cancer for Use in Development of a Liquid Biopsy Assay

for
Non-hematologic Cancer
Location: Boise ID
Sponsor: Sequenom, Inc.

Sex: All

Age: 18+

Code: NCT02586389

Recruiting

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

for
Acute Biphenotypic Leukemia, Acute Myeloid Leukemia,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT04797767

Phase 1, Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer