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Oncology Clinical Trials

Browse 9,171 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Observational Pharmaco-Epidemiology Research & Analysis

for
Chronic Disease, HIV/AIDS, Liver Diseases,
Location: Durham NC
Sponsor: Epividian

Sex: All

Age: 0+

Code: NCT03813862

Recruiting

Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100

for
Ovarian Clear Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06065462

Phase1, Phase2, Recruiting

Definitive Therapy for Oligometastatic Solid Malignancies

for
Stage IV or Recurrent Carcinoma or Sarcoma
Location: Aurora CO, Thornton CO, Littleton CO, Boulder CO
Sponsor: Rocky Mountain Cancer Centers

Sex: All

Age: 18+

Code: NCT01898962

Phase2, Recruiting

Protocol For Collecting Data On Patients With Childhood Cancer

for
Childhood Cancer
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT00684580

Recruiting

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

for
High-grade Glioma, Solid Tumor, Unspecified, Child
Location: Edison NJ, Miami FL, Little Rock AR
Sponsor: Laminar Pharmaceuticals

Sex: All

Age: 0 - 18

Code: NCT04299191

Phase1, Phase2, Recruiting

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Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study

for
Neurofibromatosis Type 1, Neurofibroma
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 5 - 70+

Code: NCT06880991

Recruiting

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

for
Pancreatic Carcinoma
Location: Boston MA, Baltimore MD, Pittsburgh PA, Atlanta GA,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06271291

Recruiting

A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...

for
B-All, Acute Lymphoblastic Leukemia
Location: Washington D.C. DC, Bethesda MD, Salt Lake City UT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 25

Code: NCT05621291

Recruiting

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

for
Thyroid Cancer, Thyroid Carcinoma, Metastatic Thyroid Cancer,
Location: Boston MA, Philadelphia PA, Washington, D.C. DC,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 12+

Code: NCT05668962

Phase2, Recruiting

High Heated Humidity in Stem Cell Transplant

for
Autologous Stem Cell Transplant
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT05358262

Phase2, Recruiting

Training Nurses in Basic Hypnoanalgesia Techniques

for
Cancer
Location: Montreal
Sponsor: St. Justine's Hospital

Sex: All

Age: 5 - 18

Code: NCT02421562

Recruiting

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New York NY, New Brunswick NJ, Orlando FL,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT05932862

Phase1, Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for
Colorectal Cancer, CRC, Pancreatic Ductal Adenocarcinoma, PDAC,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06445062

Phase1, Phase2, Recruiting

Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors

for
CNS Cancer, Head and Neck Cancer, GI Cancer, Gynecologic Cancer,
Location: New York NY
Sponsor: The New York Proton Center

Sex: All

Age: 18+

Code: NCT05313191

Recruiting

A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial

for
Bladder Cancer, Urothelial Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT06040762

Recruiting

Rowing Following Breast Cancer Chemotherapy

for
Breast Cancer Survivors
Location: Gainesville FL
Sponsor: University of Florida

Sex: Female

Age: 40 - 70+

Code: NCT05848141

Recruiting

Exploring, Predicting, and Intervening on Long-term Viral Suppression Electronically

for
HIV Infections
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18+

Code: NCT06370780

Recruiting

Making Healthy Habits Stick

for
Cancer, Physical Activity, Cancer Survivor, Cancer Survivorship
Location: Birmingham AL, Memphis TN
Sponsor: University of Tennessee

Sex: Female

Age: 19+

Code: NCT06745180

Recruiting

A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

for
Advanced Melanoma
Location: Hartford CT, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06594991

Phase2, Recruiting

In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

for
Non-Muscle Invasive Bladder Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06704191

Phase1, Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer