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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Male

Age: 18+

Code: NCT06568562

Phase2, Recruiting

Collection and Distribution of Biospecimens for Novel Research Uses

for
Cancer, Healthy, Gastrointestinal Complication,
Location: Huntsville AL
Sponsor: iSpecimen Inc

Sex: All

Age: 0 - 70+

Code: NCT03848962

Recruiting

Physical Activity and Community EmPOWERment Project

for
Intellectual Disability, Neurodevelopmental Disorders,
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18+

Code: NCT06740162

Recruiting

Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

for
Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm,
Location: Camden NJ, Jacksonville FL, Indianapolis IN, Houston TX,
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04870762

Phase2, Recruiting

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

for
High Grade Glioma, CNS Tumor
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 3

Code: NCT06528691

Phase2, Recruiting

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NSCLC Liquid Biopsies and Exhaled VOC

for
Lung Cancer, Circulating Tumor DNA
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT06707519

Recruiting

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for
Colorectal Carcinoma, Endometrial Carcinoma, Melanoma,
Location: Boston MA, New York NY, Philadelphia PA,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 30

Code: NCT04851119

Phase1, Phase2, Recruiting

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for
Chronic Pancreatitis, Exocrine Pancreas Carcinoma,
Location: Boston MA, Montreal, Philadelphia PA, Baltimore MD,
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0 - 17

Code: NCT06651580

Recruiting

A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors

for
Solid Tumor
Location: Providence RI, Philadelphia PA, Fairfax VA,
Sponsor: Chugai Pharmaceutical

Sex: All

Age: 18+

Code: NCT05907980

Phase1, Recruiting

MRI Predictors of Response to Tumor Treating Fields

for
Glioblastoma Multiforme
Location: Brooklyn NY
Sponsor: New York Presbyterian Brooklyn Methodist Hospital

Sex: All

Age: 18+

Code: NCT03642080

Recruiting

Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue

for
Bladder Cancer, Urinary Tract Cancer, Urothelial Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02379429

Recruiting

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

for
Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma,
Location: Fairfax VA, Pittsburgh PA, Canton OH, Columbus OH,
Sponsor: OncoNano Medicine, Inc.

Sex: All

Age: 18+

Code: NCT06022029

Phase1, Recruiting

A Study of Melphalan With or Without Siltuximab in People With Multiple Myeloma Having an Autologous Stem Cell Transplant

for
Multiple Myeloma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT06679829

Phase2, Recruiting

In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)

for
Chronic Lymphocytic Leukemia
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT04785989

Recruiting

Cultured Circulating Tumor Cells in Prostate and Other Cancers

for
Prostate Cancer
Location: Las Vegas NV
Sponsor: Oscar Goodman, Jr.

Sex: All

Age: 18+

Code: NCT02123862

Recruiting

Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases

for
Brain Metastases, Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05064280

Phase2, Recruiting

Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

for
Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG,
Location: Halifax, Montreal, Syracuse NY, Myrtle Beach SC,
Sponsor: Theralase® Technologies Inc.

Sex: All

Age: 18+

Code: NCT03945162

Phase2, Recruiting

Oral Minoxidil for the Treatment of Recurrent Platinum Resistant Epithelial Ovarian Cancer

for
Ovarian Cancer
Location: Maywood IL
Sponsor: Loyola University

Sex: Female

Age: 18 - 70+

Code: NCT05272462

Phase2, Recruiting

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Solid Tumors, HER2 Mutation
Location: Boston MA, Toronto, Fort Myers FL, Cleveland OH,
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06760819

Phase2, Recruiting

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

for
Non Small Cell Lung Cancer, Small Cell Lung Carcinoma,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 15+

Code: NCT05265429

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer