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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 215 people applied to oncology studies last month. Search by city or state to find one near you.

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Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

for
Head and Neck Cancer, Locally Advanced Head and Neck Carcinoma
Location: Nashville TN
Sponsor: Natalie Lockney

Sex: All

Age: 21+

Code: NCT05156060

Phase 1, Phase 2, Recruiting

PECS Block in Partial Mastectomy for Postoperative Pain Control

for
Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
Location: Philadelphia PA
Sponsor: Main Line Health

Sex: Female

Age: 18+

Code: NCT04086394

Recruiting

Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma

for
Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT03501576

Recruiting

T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer

for
Prostate Cancer
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: Male

Age: 18+

Code: NCT05586360

Phase 2, Recruiting

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Boston MA, Mineola NY, New York NY, Columbus OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05422794

Phase 1, Recruiting

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Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis

for
Cancer, Appendiceal, ColoRectal Cancer
Location: Westwood KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18 - 70+

Code: NCT03073694

Phase 2, Recruiting

Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab

for
Non-Hodgkin Lymphoma, Cytokine Release Syndrome
Location: Cleveland OH
Sponsor: Taylor Brooks

Sex: All

Age: 18 - 65

Code: NCT06447376

Phase 1, Recruiting

An Enhanced Vaginal Dilator to Reduce Radiation-Induced Vaginal Stenosis

for
Endometrial Cancer, Cervical Cancer, Vaginal Stricture,
Location: Maywood IL
Sponsor: Margaret Liotta

Sex: Female

Age: 18+

Code: NCT03876860

Recruiting

Fecal Immunochemical Test for Post-polypectomy Surveillance to Reduce Unnecessary eNdoscopy

for
Colorectal Neoplasms
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18 - 70+

Code: NCT05396560

Recruiting

Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse

for
Multiple Myeloma in Relapse
Location: New York NY
Sponsor: Larysa Sanchez

Sex: All

Age: 70+

Code: NCT06827860

Phase 2, Recruiting

Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy

for
Recurrent Glioblastoma, IDH-Wildtype,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05789394

Phase 1, Recruiting

Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

for
Endometrial Cancer, Cancer of Endometrium,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06253494

Phase 1, Phase 2, Recruiting

A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma

for
Adenoid Cystic Carcinoma
Location: Commack NY, Uniondale NY, East White Plains NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06891560

Phase 2, Recruiting

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for
Multiple Myeloma, Myeloma, Myeloma Multiple
Location: Boston MA, New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: K36 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05651932

Phase 1, Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for
Colorectal Neoplasms
Location: Shirley NY, Mineola NY, The Bronx NY, New York NY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06750094

Phase 3, Recruiting

18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery

for
Brain Metastases, Brain Metastases, Adult, Brain Cancer
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT06048094

Phase 1, Recruiting

A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

for
Small Cell Lung Cancer
Location: Boston MA, Hackensack NJ, Miami FL, Buffalo NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06780137

Phase 1, Phase 2, Recruiting

Ommaya Reservoir Placement for Brain Tumor Biomarker Access

for
Brain Tumor
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04692337

Recruiting

MB-105 in Patients With CD5 Positive T-cell Lymphoma

for
Lymphoma, T-Cell
Location: Boston MA, New York NY, Chapel Hill NC, Tampa FL,
Sponsor: March Biosciences Inc

Sex: All

Age: 18+

Code: NCT06534060

Phase 2, Recruiting

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

for
Clinical Stage III Gastric Cancer AJCC v8,
Location: Weston FL, Jacksonville FL, Nashville TN, Green Bay WI,
Sponsor: Academic and Community Cancer Research United

Sex: All

Age: 18+

Code: NCT04660760

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer