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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1

Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

for
Primary Mitochondrial Disease
Location: Marlboro NJ, Miami FL, Pittsburgh PA, Akron OH,
Sponsor: Pharming Technologies B.V.

Sex: All

Age: 18+

Code: NCT05650229

Phase2, Recruiting

Pillow Use During Total Hip Arthroplasty

for
Arthroplasty, Replacement, Hip, Hip Replacement, Total
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT03825029

Recruiting

Fludarabine and 400 CGY Total Body Irradiation for Recipients of HLA-Matched or Mis-Matched Family or Unrelated Donor Hematopoietic Stem Cell Transplants Who Have Rejected Their First Allogeneic Stem Cell Transplant

for
Graft Failure
Location: Denver CO
Sponsor: Colorado Blood Cancer Institute

Sex: All

Age: 18 - 70+

Code: NCT00472329

Phase2, Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 60+

Code: NCT06195891

Phase1, Recruiting

A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions

for
Skin Lesion, Mucosal Lesion
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0+

Code: NCT04743362

Recruiting

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Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

for
Myeloid Malignancy, Inherited Bone Marrow Failure Syndrome,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT02958462

Recruiting

JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation

for
MYELODYSPLASTIC SYNDROME; MDS, ACUTE MYELOID LEUKEMIA; AML
Location: Chicago IL, Salt Lake City UT, Seattle WA, Portland OR,
Sponsor: Jasper Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04429191

Phase1, Recruiting

Study of CB307 in Patients With Advanced and/or Metastatic PSMA-positive Tumours.

for
Advanced and/or Metastatic Solid Tumours
Location: Seattle WA
Sponsor: Crescendo Biologics Ltd.

Sex: All

Age: 18+

Code: NCT04839991

Phase1, Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Montreal, Fairfax VA, Toronto, Cleveland OH, Detroit MI,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05208762

Phase1, Recruiting

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

for
High Risk Myelodysplastic Syndrome,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03214562

Phase1, Phase2, Recruiting

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for
Neuroblastoma, Ewing Sarcoma, Osteosarcoma, Rhabdomyosarcoma,
Location: Providence RI, Hartford CT, Hackensack NJ, Montreal,
Sponsor: Milton S. Hershey Medical Center

Sex: All

Age: 0 - 30

Code: NCT06541262

Phase1, Phase2, Recruiting

Psilocybin-facilitated Treatment for Chronic Pain

for
Fibromyalgia, Primary
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 25 - 65

Code: NCT05068791

Early_phase1, Recruiting

Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT04952480

Phase2, Recruiting

Intraoperative Radiation Therapy for Resectable Pancreas Cancer

for
Pancreas Cancer
Location: Maywood IL
Sponsor: Loyola University

Sex: All

Age: 18+

Code: NCT02599662

Phase1, Recruiting

A Study of SIPLIZUMAB in AILD and LT Patients

for
Autoimmune Liver Disease, Liver Transplant Disorder,
Location: New York NY
Sponsor: Elizabeth C. Verna

Sex: All

Age: 18+

Code: NCT06455280

Phase1, Recruiting

Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix

for
Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 0+

Code: NCT05046080

Recruiting

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

for
Liver Cancer, Rhabdomyosarcoma, Malignant Rhabdoid Tumor,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 1 - 21

Code: NCT04715191

Phase1, Recruiting

Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer

for
Malignant Neoplasms of Respiratory and Intrathoracic Organs,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03114462

Phase1, Recruiting

Effect of Needle Size in Diagnostic Yield of EBUS-TBNA in Sarcoidosis and Lymphoma

for
Sarcoidosis, Lymphoma, Adenopathy Hilar
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT03573362

Recruiting

An Efficacy and Safety Study to Assess [18F]-ML-10 in Detecting Response of Tumors to Chemotherapy and Radiation

for
Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms
Location: Boston MA, New York NY, Teaneck NJ, Pittsburgh, PA
Sponsor: Aposense Ltd.

Sex: All

Age: 18+

Code: NCT01260480

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer