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Oncology Clinical Trials

Browse 9,171 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer

for
Triple Negative Breast Cancer
Location: Tampa FL, Clearwater FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05528133

Phase2, Recruiting
Active & Responsive

Breast cancEr, FITness and ExeRcise for Heart Health: The BE-FITTER Study

for
Breast Cancer, Disability Physical, Heart Failure,
Location: Edmonton
Sponsor: University of Alberta

Sex: Female

Age: 60+

Code: NCT06595147

Recruiting
Active & Responsive

Protein Needs Study

for
Colorectal Cancer, Breast Cancer
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 45 - 70+

Code: NCT04144907

Recruiting
Active & Responsive

A Pancreatic Cancer Screening Study in Hereditary High Risk Individuals

for
Pancreatic Neoplasms
Location: Norwalk CT
Sponsor: Nuvance Health

Sex: All

Age: 50 - 70+

Code: NCT03250078

Recruiting
Active & Responsive

PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

for
Cervical Cancer, Uterine Cancer, Endometrial Cancer
Location: Voorhees Township NJ, Philadelphia PA, Lancaster PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female

Age: 18+

Code: NCT05758688

Phase2, Recruiting

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Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Mineola NY, New York NY, Montreal, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase1, Phase2, Recruiting
Active & Responsive

Evaluation of the Neurologic Assessment in Pediatric Neuro-Oncology (pNANO)

for
Pediatric Brain Tumor, Pediatric Spine Tumor
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 1 - 17

Code: NCT06981156

Recruiting
Active & Responsive

Mood Alterations in the Patients With Non-Muscle Invasive Bladder Cancer Treated With BCG

for
Non-Muscle Invasive Bladder Cancer
Location: Washington D.C. DC
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT05672615

Recruiting
Active & Responsive

EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT05723107

Phase1, Recruiting
Active & Responsive

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

for
Gastrointestinal Cancer
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT06065371

Phase1, Recruiting
Active & Responsive

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for
Extensive Stage-small Cell Lung Cancer
Location: Lebanon NH, Mineola NY, New York NY, Hackensack NJ,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06362252

Phase1, Phase2, Recruiting
Active & Responsive

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for
Prostate Cancer, Prostatic Neoplasms
Location: Boston MA, New Haven CT, West Haven CT, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: Male

Age: 18+

Code: NCT06925737

Phase3, Recruiting
Active & Responsive

ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

for
Prostate Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: Male

Age: 18+

Code: NCT06397703

Phase2, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Pennington NJ, Philadelphia PA, Newark DE, Baltimore MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting
Active & Responsive

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

for
Non-small Cell Lung Cancer, NSCLC
Location: Hackensack NJ, Trois-Rivieres, Pennington NJ, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06422143

Phase3, Recruiting
Active & Responsive

Study of Cryoablation and Nirogacestat for Desmoid Tumor

for
Desmoid Tumor
Location: Palo Alto CA
Sponsor: Nam Bui

Sex: All

Age: 18+

Code: NCT05949099

Phase2, Recruiting
Active & Responsive

Study of STM-416p Administered to Patients Undergoing Radical Prostatectomy

for
Prostate Cancer
Location: Gainesville FL, Tucson AZ
Sponsor: SURGE Therapeutics

Sex: Male

Age: 18+

Code: NCT06450106

Phase1, Recruiting
Active & Responsive

Activating Cancer Communities Through an Exercise Strategy for Survivors

for
Cancer
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 18+

Code: NCT03599843

Recruiting
Active & Responsive

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for
Non-small Cell Lung Cancer, Histiocytic Neoplasm, Histiocytosis,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT05786924

Phase1, Phase2, Recruiting
Active & Responsive

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06648434

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer