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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid Tumors

for
Solid Tumor Cancer
Location: Santa Monica CA
Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All

Age: 18+

Code: NCT07671534

Phase2, Recruiting
Active & Responsive

A Mixed-Methods Metabolomics Investigation of Lifestyle and Energy Balance During Breast Cancer Survivorship

for
Breast Cancer
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female

Age: 18+

Code: NCT07655934

Recruiting
Active & Responsive

Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer

for
Small Cell Lung Cancer ( SCLC ),
Location: Indianapolis IN
Sponsor: Misty Shields

Sex: All

Age: 18+

Code: NCT07153055

Phase1, Phase2, Recruiting
Active & Responsive

Prospective Database of Clinical Outcomes Following Cryotherapy for Ablation of Clinically Localized Prostate Cancer

for
Prostate Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: Male

Age: 40 - 70+

Code: NCT07184957

Recruiting
Active & Responsive

The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey

for
Cancer
Location: Rye NY
Sponsor: Lymphoma and Leukemia Society

Sex: All

Age: 18+

Code: NCT07173322

Recruiting

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Active & Responsive

Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors

for
Breast Cancer Female, Gynecologic Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Female

Age: 18+

Code: NCT07120100

Recruiting
Active & Responsive

Novel, One Stop, Affordable, Point of Care and AI Supported System of Screening, Triage and Treatment Selection for Cervical Cancer in LMICs

for
Cervical Cancer, Screening
Location: Cincinnati OH
Sponsor: International Agency for Research on Cancer

Sex: Female

Age: 25 - 49

Code: NCT06042543

Recruiting
Active & Responsive

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for
Metastatic Castration-resistant Prostate Cancer
Location: Montreal, Miami FL, Dothan AL, Metairie LA, Omaha NE,
Sponsor: AstraZeneca

Sex: Male

Age: 18+

Code: NCT07611110

Phase3, Recruiting
Active & Responsive

A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors

for
Locally Advanced (Unresectable) or Metastatic Solid Tumors
Location: New York NY, Fairfax VA, Nashville TN, Houston TX,
Sponsor: NEOK Bio, Inc.

Sex: All

Age: 18+

Code: NCT07612176

Phase1, Recruiting
Active & Responsive

LEgal Guidance and AdvocaCY for CAREgivers (LEGACY CARE): A Pilot Clinical Trial for Caregivers of Persons With Colorectal Cancer

for
Caregiver Burden, Colorectal Cancer, Legal Intervention
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT07153016

Recruiting
Active & Responsive

ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy

for
Breast Cancer
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: Female

Age: 45 - 70+

Code: NCT06185205

Phase2, Recruiting
Active & Responsive

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

for
Small-cell Lung Cancer, Neuroendocrine Carcinomas,
Location: New York NY, Philadelphia PA, Fairfax VA, Orlando FL,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT07174583

Phase1, Phase2, Recruiting
Active & Responsive

Exploring the Feasibility of an Exercise and Noninvasive Brain Stimulation Intervention in Breast Cancer Survivors

for
Breast Cancer
Location: Boca Raton FL
Sponsor: Florida Atlantic University

Sex: All

Age: 18+

Code: NCT07587957

Recruiting
Active & Responsive

A 2-part Phase 1/2 Open-label Trial on ODM-212

for
Mesothelioma, Pancreatic Cancer,
Location: Fairfax VA, Irving TX
Sponsor: Orion Corporation, Orion Pharma

Sex: All

Age: 18+

Code: NCT07563738

Phase1, Phase2, Recruiting
Active & Responsive

CONTIGO - A Narrative Intervention to Enhance Genetic Counseling and Testing

for
Hereditary Breast and Ovarian Cancer
Location: Washington D.C. DC, Richmond VA
Sponsor: Georgetown University

Sex: Female

Age: 18+

Code: NCT05130606

Recruiting
Active & Responsive

GTB-5550 in Advanced Solid Tumors

for
Tri-specific Killer Engager, Solid Tumor, Advanced Solid Tumor
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT07541573

Phase1, Recruiting
Active & Responsive

Gemcitabine/Cisplatin Plus Cemiplimab With or Without Fianlimab in Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT)

for
Bladder Cancer, Muscle-Invasive Bladder Carcinoma
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT06571708

Phase2, Recruiting
Active & Responsive

HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT

for
Hematologic Malignancy
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06731504

Early_phase1, Recruiting
Active & Responsive

ARC101 in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Montreal, Toronto, Grand Rapids MI, San Antonio TX,
Sponsor: Third Arc Bio

Sex: All

Age: 18+

Code: NCT06672185

Phase1, Recruiting
Active & Responsive

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

for
Locally Advanced Clear Cell Renal Cell Carcinoma,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT06866262

Phase1, Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer