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Oncology Clinical Trials

Browse 9,155 oncology clinical trials enrolling across the United States and Canada. 215 people applied to oncology studies last month. Search by city or state to find one near you.

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Active & Responsive

A Study of MX006 in Patients With Advanced and/or Metastatic Tumors Known to Express B7-H3

for
Advanced and/or Metastatic Solid Tumors Known to Express B7-H3
Location: Baltimore MD, Fairfax VA, Sarasota FL, Atlanta GA,
Sponsor: Myricx Pharma Limited

Sex: All

Age: 18+

Code: NCT07807241

Phase 1, Recruiting
Active & Responsive

Advocacy, Partnership, Outreach, and Yielding Optimized Care for Oncology Patients

for
Colorectal Cancer
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT07403981

Recruiting
Active & Responsive

Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors

for
Periampullary Neoplasms, Pancreatic Cancer,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07360119

Recruiting
Active & Responsive

Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational Pathologic Analysis

for
Prostate Cancer Screening
Location: Durham NC, Hardeeville SC
Sponsor: Uro-1 Medical

Sex: Male

Age: 18+

Code: NCT06830265

Recruiting
Active & Responsive

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma,
Location: Washington D.C. DC
Sponsor: Children's National Research Institute

Sex: All

Age: 3 - 25

Code: NCT07664176

Phase 1, Recruiting

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Active & Responsive

Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)

for
Esophageal Carcinoma, Gastric Cancer (Diagnosis),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07795749

Phase 2, Recruiting
Active & Responsive

A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs)

for
Triple Negative Breast Cancer (TNBC),
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT07743190

Phase 2, Recruiting
Active & Responsive

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

for
Colorectal Neoplasms, Breast Neoplasms, Head and Neck Neoplasms,
Location: Toms River NJ, Jersey City NJ, Belleville NJ, Newark NJ,
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT07158164

Recruiting
Active & Responsive

Neoadjuvant Darolutamide Alone or in Combination With Standard Therapy for Stage II-IIIA, AR+, TNBC

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Nashville TN
Sponsor: Vandana Abramson

Sex: All

Age: 18+

Code: NCT07016399

Phase 2, Recruiting
Active & Responsive

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for
Pediatric Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT07514819

Recruiting
Active & Responsive

Stereotactic MR-Adaptive Radiation Therapy for Early-stage Renal Cancer

for
Primary Renal Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT07767500

Recruiting
Active & Responsive

NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients

for
Triple Negative Breast Cancer
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT06845319

Phase 2, Recruiting
Active & Responsive

RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer

for
Early Rectal Cancer, Stage I Rectal Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07735624

Phase 2, Recruiting
Active & Responsive

Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, Immunotherapy, Neoadjuvant Therapy
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT06743581

Recruiting
Active & Responsive

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Boston MA, New Haven CT, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07111520

Phase 1, Phase 2, Recruiting
Active & Responsive

Optimizing Ancillary Therapies With Immune Checkpoint Inhibitors for Solid Tumors (OAT ICI)

for
Solid Tumors
Location: Lexington KY
Sponsor: Val Adams

Sex: All

Age: 18 - 70+

Code: NCT07661459

Phase 2, Recruiting
Active & Responsive

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)

for
Left-sided Colorectal Cancer
Location: Savannah GA, Warner Robins GA, Indianapolis IN,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07702032

Phase 3, Recruiting
Active & Responsive

Breast Cancer Plasma Adjuvant Intra-operative Treatment (Breast Cancer PAINT)

for
Breast Cancer
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: Female

Age: 18+

Code: NCT06222788

Recruiting
Active & Responsive

Tai Chi for Reducing Aromatase Inhibitor-Induced Arthralgia

for
Hormone Receptor Positive Breast Carcinoma, Postmenopausal,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: Female

Age: 18+

Code: NCT07737951

Recruiting
Active & Responsive

Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer Liver Metastasis

for
Colorectal Adenocarcinoma Metastatic in the Liver,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07764497

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer