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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors

for
Primary Hyperparathyroidism, Parathyroid Cancer,
Location: Bethesda MD
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All

Age: 18 - 70+

Code: NCT07444723

Phase2, Phase3, Recruiting
Active & Responsive

Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

for
Colorectal Cancer
Location: New York NY, Baltimore MD, Pittsburgh PA, Louisville KY,
Sponsor: Exero Medical Ltd.

Sex: All

Age: 21+

Code: NCT07337590

Recruiting
Active & Responsive

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

for
Solid Tumor Malignancies, Colorectal Carcinoma,
Location: Philadelphia PA, Fairfax VA, Orlando FL,
Sponsor: Tasca Therapeutics

Sex: All

Age: 18+

Code: NCT07030257

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

for
Solid Tumor, Non-Small-Cell Lung Cancer,
Location: New York NY, Hackensack NJ, Fairfax VA, Buffalo NY,
Sponsor: Astellas Pharma Inc

Sex: All

Age: 18+

Code: NCT07094204

Phase1, Recruiting
Active & Responsive

Impact of Multimodal Telerehabilitation in Rural Patients With Metastatic Prostate Cancer

for
Prostate Cancer, Metastatic Prostate Cancer,
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Male

Age: 21+

Code: NCT07032584

Recruiting

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Active & Responsive

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

for
Triple Negative Breast Cancer, HER2-negative Breast Cancer,
Location: Fairfax VA, Orlando FL, Huntersville NC, Sarasota FL,
Sponsor: Dren Bio

Sex: All

Age: 18+

Code: NCT06999187

Phase1, Recruiting
Active & Responsive

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for
Lung Cancer Diagnosis
Location: Hyannis MA, Stamford CT, Mullica Hill NJ,
Sponsor: Freenome Holdings Inc.

Sex: All

Age: 50+

Code: NCT06122077

Recruiting
Active & Responsive

A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.

for
Metastatic Solid Tumors
Location: Nashville TN, Houston TX, Irving TX, San Antonio TX,
Sponsor: Erasca, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07021898

Phase1, Recruiting
Active & Responsive

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

for
Prostate Cancer,
Location: Myrtle Beach SC, Charlottesville VA, Tampa FL,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male

Age: 18+

Code: NCT07005154

Phase2, Recruiting
Active & Responsive

A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for
Solid Tumor Malignancies
Location: New Haven CT, Fairfax VA, Jacksonville FL, Sarasota FL,
Sponsor: Kumquat Biosciences Inc.

Sex: All

Age: 18+

Code: NCT06994806

Phase1, Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase3, Recruiting
Active & Responsive

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for
Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm,
Location: Boston MA, New York NY, Toronto, Hamilton, Tampa FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07114601

Phase1, Recruiting
Active & Responsive

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer,
Location: Boston MA, Providence RI, Worcester MA, Hartford CT,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT06901531

Phase3, Recruiting
Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Boston MA, Fairfax VA, Orlando FL, Huntersville NC,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase1, Phase2, Recruiting
Active & Responsive

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

for
Neuroblastoma, Rhabdomyosarcoma, Synovial Sarcoma,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 25

Code: NCT06625190

Phase1, Phase2, Recruiting
Active & Responsive

Mayo Clinic Radiotherapy Patient Outcomes Registry and Biobanking Study

for
Solid Tumors, Hematologic Malignancies
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 0+

Code: NCT02457962

Recruiting
Active & Responsive

Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia

for
Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18 - 70+

Code: NCT07071155

Early_phase1, Recruiting
Active & Responsive

The Cancer Stage Shifting Initiative: Registry and Biorepository to Research and Address Health Disparities in Cancer Care

for
Cancer, Cancer Comorbidities
Location: Flint MI, Houston TX
Sponsor: National Minority Quality Forum

Sex: All

Age: 35+

Code: NCT07461493

Recruiting
Active & Responsive

Study to Identify Biomarkers of Oral Cavity Cancer Response to Neoadjuvant Immunotherapy Prior to Definitive Surgery

for
Oral Cavity Cancer
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT07343596

Recruiting
Active & Responsive

Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening

for
Hereditary Cancer Syndrome
Location: New York NY
Sponsor: Columbia University

Sex: Female

Age: 18 - 55

Code: NCT07195071

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer