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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 215 people applied to oncology studies last month. Search by city or state to find one near you.

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Active & Responsive

A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

for
IO Resistant Squamous and Nonsquamous NSCLC
Location: New York NY, Washington D.C. DC, Margate FL, Tamarac FL,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07217301

Phase 3, Recruiting
Active & Responsive

A Study of DM005 in Patients With Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Fairfax VA, Detroit MI, Dallas TX
Sponsor: Doma Biopharmaceutical(Suzhou)Co., Ltd.

Sex: All

Age: 18+

Code: NCT06515990

Phase 1, Phase 2, Recruiting
Active & Responsive

IKS014 in Advanced Solid Tumors That Express HER2

for
Breast Cancer, Gastric Cancer, Gastroesophageal-junction Cancer
Location: Boston MA, Nashville TN, Fort Worth TX,
Sponsor: Iksuda Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT05872295

Phase 1, Recruiting
Active & Responsive

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

for
Castration-Resistant Prostate Cancer (CRPC), Colorectal Cancer,
Location: Dothan AL, Grand Rapids MI, Omaha NE, Houston TX
Sponsor: Radiopharm Theranostics, Ltd

Sex: All

Age: 18+

Code: NCT07189871

Phase 1, Phase 2, Recruiting
Active & Responsive

Cognitive Impact of Neoadjuvant Chemotherapy for Gynecologic Cancers

for
Ovarian Cancer, Cognitive Change
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: Female

Age: 18+

Code: NCT07125209

Recruiting

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Active & Responsive

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

for
NF1, Neurofibromatosis, Cutaneous Neurofibroma, Neurofibroma,
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT07102394

Phase 1, Recruiting
Active & Responsive

Testing the Feasibility of a Virtual Application to Support Breast and Colorectal Cancer Survivors

for
Breast Cancer Survivor, Colorectal Cancer Survivors
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 18+

Code: NCT07312786

Recruiting
Active & Responsive

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

for
Prostate Cancer Patients Treated by Radiotherapy,
Location: Saddle Brook NJ, Towson MD, Myrtle Beach SC,
Sponsor: Candel Therapeutics, Inc.

Sex: Male

Age: 18+

Code: NCT07332000

Phase 2, Recruiting
Active & Responsive

Study of PAT in Patients With Solid Tumor Cancers

for
Metastasis, Solid Tumor
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT05338658

Phase 1, Recruiting
Active & Responsive

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for
Colorectal Cancer, Colorectal Cancer (CRC),
Location: Fairfax VA, Jacksonville FL, Atlanta GA,
Sponsor: Cartography Biosciences

Sex: All

Age: 18+

Code: NCT07321106

Phase 1, Recruiting
Active & Responsive

Head and Neck Cancer Study Project in the Geriatric Population

for
Head and Neck Neoplasms
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 65+

Code: NCT06998069

Phase 3, Recruiting
Active & Responsive

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

for
AML With Gene Mutations
Location: New York NY, College Park MD, Chapel Hill NC,
Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All

Age: 18+

Code: NCT06366789

Phase 1, Recruiting
Active & Responsive

Use of a Decision Aid to Resolve Uncertainty About Radioactive Iodine Treatment in Patients With Intermediate Risk Thyroid Cancer

for
Thyroid Cancer
Location: Washington D.C. DC, Falls Church VA
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT06980103

Recruiting
Active & Responsive

Efficacy and Safety of a Single Dose of LS301-IT for Fluorescence Intraoperative Molecular Imaging (IMI) for Patients Undergoing Lung Cancer Resection for Non Small Cell Lung Cancer

for
Non Small Cell Lung Cancer (NSCLC)
Location: Philadelphia PA, Dallas TX
Sponsor: Integro Theranostics

Sex: All

Age: 18+

Code: NCT07276789

Phase 2, Recruiting
Active & Responsive

Amping up With PemJAK

for
Non-Hodgkin Lymphoma, Hodgkin Disease Lymphoma,
Location: New York NY
Sponsor: Seda S. Tolu

Sex: All

Age: 18 - 70+

Code: NCT07283822

Phase 2, Recruiting
Active & Responsive

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

for
Prostate Cancer Patients, Non-castrate Prostate Cancer,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: Male

Age: 18+

Code: NCT07090148

Phase 1, Recruiting
Active & Responsive

Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma

for
Melanoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06961357

Phase 1, Phase 2, Recruiting
Active & Responsive

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

for
Brain Neoplasms
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18 - 70+

Code: NCT07111182

Recruiting
Active & Responsive

Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

for
Glioblastoma
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06831526

Early Phase 1, Recruiting
Active & Responsive

Language Network Prehab Via fMRI Neurofeedback

for
Glioma, Glioma Surgery
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT07488780

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer