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Oncology Clinical Trials

Browse 9,272 oncology clinical trials enrolling across the United States and Canada. 215 people applied to oncology studies last month. Search by city or state to find one near you.

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Active & Responsive

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

for
Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL),
Location: Cincinnati OH, Grand Rapids MI, Chicago IL, St Louis MO,
Sponsor: Umoja Biopharma

Sex: All

Age: 18+

Code: NCT06528301

Phase 1, Recruiting
Active & Responsive

Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome

for
Recurrent Transformed Chronic Lymphocytic Leukemia,
Location: New York NY, Columbus OH, Salt Lake City UT
Sponsor: Aseel Alsouqi

Sex: All

Age: 18+

Code: NCT05873712

Phase 2, Recruiting
Active & Responsive

Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment

for
Oral Neoplasm
Location: London, Edmonton
Sponsor: Proteocyte Diagnostics Inc.

Sex: All

Age: 15 - 70+

Code: NCT04622462

Recruiting
Active & Responsive

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

for
Graft-Versus-Host Disease, Graft-versus-leukemia,
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 60

Code: NCT00001529

Recruiting
Active & Responsive

Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for
Lymphoid Leukemia
Location: Boston MA, The Bronx NY, New Castle DE, Baltimore MD,
Sponsor: Stanford University

Sex: All

Age: 0 - 26

Code: NCT05865301

Recruiting

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Active & Responsive

Quebec Pancreas Cancer Study

for
Pancreas Cancer, Pancreatic Cancer, Pancreas Neoplasm,
Location: Montreal
Sponsor: George Zogopoulos

Sex: All

Age: 18+

Code: NCT04104230

Recruiting
Active & Responsive

In Vivo Liquid Biopsy of Melanoma (Cytophone)

for
Melanoma, Circulating Tumor Cells, Metastatic Melanoma,
Location: Madison WI
Sponsor: Cytoastra

Sex: All

Age: 18 - 70+

Code: NCT06488365

Recruiting
Active & Responsive

Rare Embryonal Tumors of the Central Nervous System: International Registry

for
Embryonal Tumor
Location: Ottawa
Sponsor: Immune Oncology Research Institute

Sex: All

Age: 0 - 25

Code: NCT05711992

Recruiting
Active & Responsive

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

for
Acute Myeloid Leukemia
Location: Columbus OH
Sponsor: Uma Borate

Sex: All

Age: 18+

Code: NCT06930352

Phase 2, Recruiting
Active & Responsive

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

for
Acute Leukemia, Myelodysplastic Syndrome
Location: Palo Alto CA
Sponsor: Laguna Biotherapeutics, Inc.

Sex: All

Age: 1 - 39

Code: NCT07573111

Phase 1, Recruiting
Active & Responsive

CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia

for
Acute Myeloid Leukemia (AML)
Location: Philadelphia PA
Sponsor: Stephan Grupp MD PhD

Sex: All

Age: 0 - 29

Code: NCT07464951

Phase 1, Recruiting
Active & Responsive

A Study of the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone in People With Acute Myeloid Leukemia

for
Acute Myeloid Leukemia
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT07392242

Phase 2, Recruiting
Active & Responsive

UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML

for
Acute Myeloid Leukemia, Pediatric AML
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 30

Code: NCT07059975

Early Phase 1, Recruiting
Active & Responsive

Venetoclax Plus Zanubrutinib for the Treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Columbus OH
Sponsor: Kerry Rogers

Sex: All

Age: 18+

Code: NCT07734038

Phase 2, Recruiting
Active & Responsive

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Chronic Myeloid Leukemia in Chronic Phase After Failing One Prior Therapy With a Second Generation Tyrosine Kinase Inhibitor or Asciminib

for
Chronic Myeloid Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06817720

Phase 2, Recruiting
Active & Responsive

Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia

for
T-cell Prolymphocytic Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07311746

Phase 1, Phase 2, Recruiting
Active & Responsive

CD64 CAR T Cell Therapy in Adults With Relapsed and/or Refractory AML

for
Refractory Acute Myeloid Leukemia (AML),
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18+

Code: NCT07347418

Phase 1, Recruiting
Active & Responsive

FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0 - 6

Code: NCT06609928

Phase 1, Recruiting
Active & Responsive

Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia, TP53
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT07008638

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies

for
CLL / SLL, CLL (Chronic Lymphocytic Leukemia),
Location: Chapel Hill NC, Columbus OH, Cincinnati OH,
Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All

Age: 18+

Code: NCT06708897

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer