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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation

for
Myeloproliferative Neoplasms
Location: Chicago IL, Milwaukee WI
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06291987

Phase1, Recruiting

Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer

for
Breast Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT05042687

Recruiting

Radiotherapy to Consolidate Systemic Response in Metastatic Prostate Cancer (ANCHOR-Prostate)

for
Prostate Cancer Metastatic
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: Male

Age: 0+

Code: NCT05457699

Phase2, Recruiting

Vincere Biobank Research Protocol

for
Cancer
Location: Scottsdale AZ
Sponsor: Vincere Cancer Center

Sex: All

Age: 18+

Code: NCT05954299

Recruiting

Auditory Brainstem Implant (ABI) in Children With No Cochleae or Auditory Nerves

for
Hearing Loss, Bilateral (Causes Other Than Tumors)
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 1 - 21

Code: NCT02310399

Recruiting

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Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Duarte CA, Alhambra CA, Pasadena CA, Burbank CA,
Sponsor: Jonsson Comprehensive Cancer Center

Sex: Female

Age: 0+

Code: NCT05595499

Phase2, Recruiting

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

for
Renal Tumor Histology, Cutaneous Leiomyoma, Kidney Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2+

Code: NCT00050752

Recruiting

Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer

for
Inflammatory Breast Carcinoma, Invasive Breast Carcinoma,
Location: Jacksonville FL, Nassau Bay TX, Houston TX,
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00477100

Recruiting

Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

for
Breast Neoplasm Female
Location: Madison WI, Iowa City IA
Sponsor: University of Wisconsin, Madison

Sex: Female

Age: 18+

Code: NCT03096418

Recruiting

Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas

for
Neoplasm Metastases, Metastases, Neoplasm
Location: Toms River NJ, Lakewood NJ, Livingston NJ,
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT05419518

Phase2, Recruiting

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

for
Neuroendocrine Tumors Unresectable,
Location: Baltimore MD, Fairfax VA, Chapel Hill NC, Miami FL,
Sponsor: Perspective Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05636618

Phase1, Phase2, Recruiting

A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer

for
HR+/HER2-negative Breast Cancer
Location: Boston MA, Philadelphia PA, Fairfax VA, Nashville TN,
Sponsor: Totus Medicines

Sex: Female

Age: 18+

Code: NCT05683418

Phase1, Recruiting

Screening Strategies Among High-risk Populations for Anal Cancer

for
Neoplasms, HPV-Related Anal Squamous Cell Carcinoma
Location: Miami FL, Atlanta GA
Sponsor: Lisa Flowers

Sex: All

Age: 30 - 70+

Code: NCT06628570

Recruiting

Stereotactic Radiotherapy (SBRT) of Lung Metastasis

for
Non-small Cell Lung Cancer, Metastasis From Other Cancers
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT01803542

Phase2, Recruiting

BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer

for
Breast Cancer
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18+

Code: NCT06085742

Phase2, Recruiting

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer
Location: New Haven CT, New York NY, Philadelphia PA, Fairfax VA,
Sponsor: Amgen

Sex: Male

Age: 18+

Code: NCT04221542

Phase1, Recruiting

CfDNA in Hereditary And High-risk Malignancies 2

for
Hereditary Cancer Syndrome
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 0 - 70+

Code: NCT06726642

Recruiting

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma,
Location: Boston MA, Providence RI, New York NY, Charleston SC,
Sponsor: Bicara Therapeutics

Sex: All

Age: 18+

Code: NCT04429542

Phase1, Recruiting

LIFE Cancer Survivorship Database for Pediatric Cancer

for
Pediatric Cancer
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 0+

Code: NCT01518400

Recruiting

Endometrial Cancer, Risk Factors and Prevention Strategies: Perspectives of Patients and At-Risk Women

for
Endometrial Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT06409052

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer