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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors

for
Neoplasms, Neoplasm Metastasis, Non-Small-Cell Lung Cancer
Location: Boston MA, Canton OH, Detroit MI
Sponsor: Shanghai EpimAb Biotherapeutics Co., Ltd.

Sex: All

Age: 18+

Code: NCT03797391

Phase 1, Phase 2, Recruiting

Stereotactic Body Radiation and Tumor Treating Fields for Locally Advanced Pancreas Cancer

for
Pancreas Cancer, Locally Advanced,
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05679674

Recruiting

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

for
Solid Tumor, Advanced Cancer, Metastatic Cancer,
Location: Tampa FL
Sponsor: Memgen, Inc.

Sex: All

Age: 18+

Code: NCT05076760

Phase 1, Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase 2, Recruiting

Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06565260

Recruiting

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Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

for
Breast Carcinoma, Esophageal Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00991094

Recruiting

Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

for
Cancer, Head and Neck Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06667427

Recruiting

A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias

for
Refractory Acute Leukemia, Pediatric Relapsed
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 2 - 21

Code: NCT06397027

Phase 1, Recruiting

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

for
Advanced Breast Carcinoma, Advanced Endometrial Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05092373

Phase 1, Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

for
Malignant Solid Tumors, Other Neoplasms Solid Tumors,
Location: Bethesda MD, Houston TX, Portland OR
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT03739827

Recruiting

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

for
Malignant Solid Neoplasm,
Location: Bethesda MD, Jacksonville FL, Rochester MN,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03750227

Phase 3, Recruiting

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for
Lymphoma, Malignant Solid Neoplasm
Location: Lake Success NY, Chesapeake VA, Newark DE, Scranton PA,
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT05006482

Phase 3, Recruiting

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

for
Advanced Malignant Solid Neoplasm,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT05705492

Phase 2, Recruiting

Breast Cancer Liquid Biopsy Trial

for
Breast Cancer, Cancer
Location: Bronx NY, New York NY, Hollywood FL, Orlando FL,
Sponsor: Anthony Magliocco

Sex: All

Age: 18+

Code: NCT04962529

Recruiting

Study of XB010 in Subjects With Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors,
Location: The Bronx NY, Fairfax VA, Orlando FL, Atlanta GA,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT06545331

Phase 1, Recruiting

Comprehensive Outcomes for After Cancer Health

for
Ovarian Cancer, Breast Cancer, Lung Cancer, Gastric Cancer,
Location: Boston MA, Houston TX
Sponsor: Pack Health

Sex: All

Age: 18+

Code: NCT05349227

Recruiting

Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases

for
Metastatic Malignant Neoplasm in the Bone,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06549478

Phase 1, Recruiting

Imaging Study of [89Zr]DFO-YS5 for Cancer Detection

for
Bladder Cancer, Nerve Sheath Tumor, Nerve Sheath Tumors,
Location: San Francisco CA
Sponsor: Robert Flavell, MD, PhD

Sex: All

Age: 18+

Code: NCT07664397

Phase 1, Recruiting

A Pilot Study Assessing Myokines During an EXErcise Regimen After Treatment for Breast Cancer

for
Cancer, Breast Cancer
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female

Age: 20 - 70+

Code: NCT07698314

Recruiting

Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

for
Graft Versus Host Disease,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 7+

Code: NCT07235501

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer