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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Dose-escalation Study of Oral CX-4945

for
Advanced Solid Tumors, Breast Cancer,
Location: Houston TX, Fort Collins CO, Loveland CO, Scottsdale AZ
Sponsor: Cylene Pharmaceuticals

Sex: All

Age: 18+

Code: NCT00891280

Phase 1, Recruiting

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for
Papillary Thyroid Cancer, Pediatric Cancer,
Location: Boston MA, Philadelphia PA, Atlanta GA, Memphis TN,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0+

Code: NCT05024929

Recruiting

Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer

for
Prostate Cancer, Refractory Cancer,
Location: Winston-Salem NC, Salisbury NC
Sponsor: Wake Forest University Health Sciences

Sex: Male

Age: 18+

Code: NCT04337580

Phase 2, Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor

for
Neoplasms, Tenosynovial Giant Cell Tumor
Location: Beverly Hills CA
Sponsor: Abbisko Therapeutics Co, Ltd

Sex: All

Age: 18+

Code: NCT04192344

Phase 1, Recruiting

Cancer Genetic Testing in Ethnic Populations

for
Breast Carcinoma, Carcinoma of Unknown Primary,
Location: Jacksonville FL, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04475640

Recruiting

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INTERogating Cancer for Etiology, Prevention and Therapy Navigation

for
Cancer, Cancer Gene Mutation, PAN Gene Mutation,
Location: Jacksonville FL, La Crosse WI, Eau Claire WI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06008392

Recruiting

Lurbinectedin in FET-Fused Tumors

for
Ewing Sarcoma, Desmoplastic Small Round Cell Tumor,
Location: Boston MA, New York NY, Philadelphia PA, Ann Arbor MI,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 10+

Code: NCT05918640

Phase 1, Phase 2, Recruiting

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

for
Anatomic Stage III Breast Cancer AJCC v8,
Location: Boston MA, Pittsburgh PA, Houston TX, Newport Beach CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT05372640

Phase 1, Recruiting

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

for
Solid Tumor, Adult, Triple Negative Breast Cancer,
Location: Scottsdale AZ, La Jolla CA, Stanford CA
Sponsor: BioEclipse Therapeutics

Sex: All

Age: 18+

Code: NCT04282044

Phase 1, Recruiting

Synapse 3D With Intravascular Indocyanine Green

for
Non-small Cell Lung Cancer, Primary Neoplasm
Location: Hamilton
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 18+

Code: NCT03953144

Phase 1, Phase 2, Recruiting

Trial of DFP-14927 in Advanced Solid Tumors

for
Solid Tumor, Cancer
Location: Houston TX, Los Angeles CA
Sponsor: Delta-Fly Pharma, Inc.

Sex: All

Age: 18+

Code: NCT03943004

Phase 1, Recruiting

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

for
Rectal Adenocarcinoma, Clinical Stage: Stage II (T3-4, N-),
Location: Hartford CT, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04165772

Phase 2, Recruiting

Registry of Older Patients With Cancer

for
Chronic Myeloproliferative Disorders,
Location: Morehead City NC, New Bern NC, Greenville NC,
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 65+

Code: NCT01137825

Recruiting

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for
Solid Tumor, Adult, Refractory Cancer,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: GV20 Therapeutics

Sex: All

Age: 18+

Code: NCT05669430

Phase 1, Phase 2, Recruiting

Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer

for
Metastatic Cancer, Oligoprogressive
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT04989725

Phase 2, Recruiting

Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study

for
Hematopoietic and Lymphoid System Neoplasm,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05772130

Recruiting

Tumor Related Epilepsy

for
Epilepsy, Cancer, Brain Neoplasm
Location: Bethesda MD
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All

Age: 8 - 70+

Code: NCT02639325

Recruiting

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

for
Advanced Malignant Solid Neoplasm, RAS Mutation, Lung Cancer,
Location: Nashville TN, Denver CO, Los Angeles CA
Sponsor: RasCal Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04678648

Phase 1, Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

for
NSCLC, HNSCC, Melanoma, Metastatic Cancer, Advanced Solid Tumor,
Location: Pittsburgh PA, Irvine CA
Sponsor: CJ Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05877430

Phase 1, Phase 2, Recruiting

Novel Serum Markers for Monitoring Response to Anti-Cancer Therapy

for
Carcinomas (Including Squamous Cell and Adenocarcinoma),
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT00349830

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer