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Oncology Clinical Trials

Browse 8,894 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for
Pediatric Patients Treated With Radiation Therapy
Location: Boston MA, New York NY, Somerset NJ, Philadelphia PA,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 0 - 21

Code: NCT01696721

Recruiting

Selinexor, Venetoclax, and Dexamethasone (XVenD) in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma

for
Relapsed and Refractory Multiple Myeloma
Location: Deerfield Beach FL, Miami FL, Coral Gables FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT05530421

Phase2, Recruiting

Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)

for
Brain Metastases
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05700721

Phase2, Recruiting

Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax

for
Stage 4 NSCLC, Radiotherapy
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT06262321

Phase2, Recruiting

A Phase II Study Of Gliadel, Concomitant Temozolomide And Radiation, Followed By Dose Dense Therapy With Temozolomide Plus Bevacizumab For Newly Diagnosed Malignant High Grade Glioma

for
Glioma
Location: Louisville KY
Sponsor: Kentuckiana Cancer Institute

Sex: All

Age: 18 - 70+

Code: NCT00660621

Phase2, Recruiting

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Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

for
Neuroblastoma
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0 - 30

Code: NCT02605421

Phase2, Recruiting

Baricitinib for Reduction of HIV - CNS

for
Human Immunodeficiency Virus
Location: Atlanta GA
Sponsor: William Tyor

Sex: All

Age: 18 - 65

Code: NCT05452564

Phase2, Recruiting

Liver Transplantation for Unresectable Liver Limited Colorectal Metastases

for
Unresectable Liver-limited Colorectal Metastases
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18 - 65

Code: NCT04742621

Recruiting

Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

for
Hematopoietic Stem Cell Transplant
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT05945121

Recruiting

Pilot Trial of Fecal Microbiota Transplantation for Lymphoma Patients Receiving Axicabtagene Ciloleucel Therapy.

for
Lymphoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06218602

Phase2, Recruiting

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

for
Locally Advanced Malignant Solid Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 16+

Code: NCT04879121

Phase2, Recruiting

Evaluation of Outcomes of the Triathlon Hinge Knee (THK) System

for
Knee Arthropathy, Recurrence, Knee Infection
Location: Weston FL, Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 0+

Code: NCT06379321

Recruiting

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

for
Multiple Myeloma
Location: New Haven CT, New York NY, Richmond VA, Rochester NY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06500884

Phase2, Recruiting

Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial

for
Ewing Sarcoma, Round Cell Sarcoma With EWSR1-non-ETS Fusion
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 2+

Code: NCT07188532

Recruiting

Developing Fast Pediatric Imaging

for
Pediatric Low-grade Gliomas
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT03761121

Recruiting

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD

for
Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD),
Location: Edison NJ
Sponsor: Bionic Sight LLC

Sex: All

Age: 50 - 70+

Code: NCT07158775

Phase1, Phase2, Recruiting

Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Livingston NJ, New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT05296421

Recruiting

Prophylactic Radiotherapy of MInimally Symptomatic Spinal Disease

for
Spine Metastases
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT05534321

Phase1, Phase2, Recruiting

Mosunetuzumab With Lenalidomide Augmentation as First-line Therapy for Follicular and Marginal Zone Lymphoma

for
Follicular Lymphoma, Marginal Zone Lymphoma, B-cell Lymphoma
Location: Providence RI, New Brunswick NJ
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT04792502

Phase2, Recruiting

Enhancing Rehabilitation Participation in Patients With SCI/D Using Motivational Interviewing

for
Spinal Cord Injuries (SCI), Spinal Cord Disease
Location: Chicago IL, Dallas TX, Seattle WA
Sponsor: Shirley Ryan AbilityLab

Sex: All

Age: 18+

Code: NCT07364773

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer