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Oncology Clinical Trials

Browse 8,894 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)

for
Glioma of Spinal Cord, Glioma of Brainstem
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 2 - 60

Code: NCT04196413

Phase1, Recruiting

Auto Stem Cell Transplant for Lymphoma Patients

for
Non-Hodgkin Lymphoma, Hodgkin Lymphoma
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0 - 70+

Code: NCT03125642

Phase2, Recruiting

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: New Haven CT, Mineola NY, New York NY, Chicago IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05272384

Phase1, Recruiting

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma

for
Squamous Cell Carcinoma of the Oropharynx
Location: Richmond VA, Charlottesville VA, Miami FL
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT05962242

Phase2, Recruiting

Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Montreal, Deerfield Beach FL, Miami FL, Coral Gables FL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06057402

Recruiting

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Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer

for
Pancreatic Cyst, Pancreas Disease
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT03260842

Recruiting

Optimizing lymphoDepletion to Improve Outcomes In Patients Receiving Cell Therapy With Yescarta

for
DLBCL - Diffuse Large B Cell Lymphoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05950802

Phase1, Recruiting

NIAID Centralized Sequencing Protocol

for
Atopy, Primary Immunodeficiency, Autoimmunity, Autoinflammation
Location: Washington D.C. DC, Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 0 - 70+

Code: NCT03206099

Recruiting

Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma

for
Glioblastoma, Recurrent Glioblastoma
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT04590664

Phase1, Phase2, Recruiting

Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Liver Tumor Research Consortium Initiative

for
Relapsed Hepatoblastoma, Refractory Hepatoblastoma
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT05556642

Recruiting

Lerapolturev (PVSRIPO) in GBM

for
Recurrent Supratentorial Glioblastoma
Location: Durham NC
Sponsor: Darell Bigner

Sex: All

Age: 18+

Code: NCT06177964

Phase2, Recruiting

The Efficacy of Intra-articular Triamcinolone Acetonide 5mg vs. 10 mg vs. 40 mg in Patients With Knee Osteoarthritis

for
Primary Gonarthrosis
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 50+

Code: NCT05806021

Recruiting

Hybrid Evaluation of a Home-based HIV Pre-exposure Prophylaxis Program

for
HIV Prevention, Pre-exposure Prophylaxis, STI
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT05856942

Recruiting

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Location: Fairhaven MA, Boston MA, Stony Brook NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06129864

Phase3, Recruiting

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for
HIV Infection, Tobacco-Related Carcinoma
Location: The Bronx NY, New York NY, Philadelphia PA,
Sponsor: AIDS Malignancy Consortium

Sex: All

Age: 45 - 70+

Code: NCT04949464

Recruiting

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma

for
Prostate Adenocarcinoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male

Age: 18+

Code: NCT04945642

Recruiting

Biologics And Clinical Immunology Cohort at Sinai

for
Immunological Disease, Autoimmune Diseases,
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 12+

Code: NCT04784364

Recruiting

Gemcitabine + Docetaxel + Toripalimab Induction in Epstein-Barr Virus (EBV) Associated Nasopharyngeal Carcinoma(NPC)

for
Nasopharyngeal Carcinoma
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06592599

Phase2, Recruiting

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

for
Primary Generalized Tonic-Clonic Seizures
Location: Chestnut Hill MA, Hackensack NJ, Montreal,
Sponsor: Xenon Pharmaceuticals Inc.

Sex: All

Age: 12+

Code: NCT05667142

Phase3, Recruiting

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

for
Ductal Carcinoma in Situ
Location: Pittsburgh PA
Sponsor: Finn, Olivera, PhD

Sex: Female

Age: 18+

Code: NCT06218303

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer