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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors

for
Neuroendocrine Carcinomas, Neuroendocrine Tumors,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06041516

Phase 1, Recruiting

Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12 - 70+

Code: NCT04744116

Early Phase 1, Recruiting

Gemcitabine + Docetaxel + Toripalimab Induction in Epstein-Barr Virus (EBV) Associated Nasopharyngeal Carcinoma(NPC)

for
Nasopharyngeal Carcinoma
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06592599

Phase 2, Recruiting

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

for
Triple Negative Breast Cancer, Breast Cancer,
Location: Boston MA, New York NY, Fairfax VA, Jacksonville FL,
Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05377996

Phase 1, Phase 2, Recruiting

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

for
Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, PDAC,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06122896

Early Phase 1, Recruiting

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T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer, Squamous Cell Carcinoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02133196

Phase 2, Recruiting

A Study of NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Ductal Adenocarcinoma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05851924

Phase 2, Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

for
B-cell Lymphoma, Non-Hodgkin Lymphoma, B-cell Malignancy,
Location: St Louis MO, Westwood KS, San Antonio TX,
Sponsor: CRISPR Therapeutics AG

Sex: All

Age: 18+

Code: NCT05643742

Phase 1, Phase 2, Recruiting

Raman Spectroscopy and Skin Cancer

for
Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
Location: Stony Brook NY
Sponsor: Tiezhi Zhang

Sex: All

Age: 18+

Code: NCT06384924

Recruiting

Study of SIRPant-M in Participants With Relapsed or Refractory Non-Hodgkin's Lymphoma

for
Refractory Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma
Location: Hackensack NJ, Houston TX, Duarte CA
Sponsor: SIRPant Immunotherapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05967416

Phase 1, Recruiting

Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy

for
Acute Myeloid Leukemia, IDH1 Mutation
Location: Miami FL
Sponsor: Justin Watts, MD

Sex: All

Age: 18 - 70+

Code: NCT06782542

Phase 2, Recruiting

Extralevator Versus Standard Abdominoperineal Resection For Rectal Adenocarcinoma

for
Rectal Adenocarcinoma
Location: Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18+

Code: NCT01702116

Recruiting

Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy

for
Urothelial Carcinoma Bladder
Location: Gainesville FL
Sponsor: University of Florida

Sex: Female

Age: 18 - 70+

Code: NCT06184516

Phase 2, Recruiting

Early Alimentation Following Colorectal Surgery

for
Colorectal Neoplasms, Crohn Disease
Location: Montreal
Sponsor: Maisonneuve-Rosemont Hospital

Sex: All

Age: 18+

Code: NCT00290524

Phase 3, Recruiting

This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.

for
Recurrent Prostate Cancer After Surgery
Location: Rochester NY
Sponsor: University of Rochester

Sex: Male

Age: 18+

Code: NCT05946824

Phase 2, Recruiting

Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Liver Tumor Research Consortium Initiative

for
Relapsed Hepatoblastoma, Refractory Hepatoblastoma
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT05556642

Recruiting

64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

for
Metastatic Sarcoma, Esophageal Cancer, Gastric Cancer,
Location: Cincinnati OH, Grand Rapids MI, Duarte CA, Orange CA,
Sponsor: Lantheus Medical Imaging

Sex: All

Age: 15+

Code: NCT06298916

Phase 1, Phase 2, Recruiting

Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer

for
Pancreatic Cyst, Pancreas Disease
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT03260842

Recruiting

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

for
Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Location: Providence RI, Bel Air MD, Baltimore MD,
Sponsor: NRG Oncology

Sex: Female

Age: 18+

Code: NCT05646316

Phase 3, Recruiting

Groningen International Study on Sentinel Nodes in Vulvar Cancer-III

for
Vulvar Cancer, Sentinel Lymph Node, Lymph Node Metastases
Location: Providence RI, Springfield MA, Commack NY, Uniondale NY,
Sponsor: University Medical Center Groningen

Sex: Female

Age: 18+

Code: NCT05076942

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer