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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 219 people applied to oncology studies last month. Search by city or state to find one near you.

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Spinal Anesthesia For Enhanced Recovery After Liver Surgery

for
Hepatectomy, Pain, Postoperative, Liver Neoplasms
Location: Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 18+

Code: NCT03715517

Recruiting

Prehabilitation to Improve Cancer Surgery Outcomes

for
Gastrointestinal Cancer, Prehabilitation, Surgery,
Location: Toronto
Sponsor: Mount Sinai Hospital, Canada

Sex: All

Age: 18+

Code: NCT03502317

Recruiting

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for
Basal Ganglia Germinoma, Diabetes Insipidus, Germinoma,
Location: Halifax, Scarborough ME, Boston MA, Providence RI,
Sponsor: Children's Oncology Group

Sex: All

Age: 3 - 29

Code: NCT06368817

Phase 2, Recruiting

Statins and Breast Cancer Biomarkers

for
Breast Cancer
Location: Boston MA, Burlington VT, Newark DE, Goldsboro NC,
Sponsor: University of Vermont

Sex: Female

Age: 35 - 55

Code: NCT00914017

Phase 2, Recruiting

A Multi-Institutional Registry for CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)

for
Breast Cancer
Location: Washington DC
Sponsor: Georgetown University

Sex: Female

Age: 50 - 70+

Code: NCT02457117

Recruiting

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The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in Reducing Opioid Prescription.

for
Fibroid Uterus
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: Female

Age: 18+

Code: NCT06536517

Phase 2, Recruiting

Developing Fast Pediatric Imaging

for
Pediatric Low-grade Gliomas
Location: Boston MA
Sponsor: Boston Children's Hospital

Sex: All

Age: 0+

Code: NCT03761121

Recruiting

Clinical Outcomes of the Endoscopic Resection of Premalignant and Malignant Gastrointestinal Lesions

for
Gastrointestinal Neoplasms, Benign Neoplasm of Intestinal Tract
Location: San Francisco CA
Sponsor: California Pacific Medical Center Research Institute

Sex: All

Age: 18+

Code: NCT01750619

Recruiting

Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma

for
Diffuse Large B-Cell Lymphoma, High-grade B-cell Lymphoma,
Location: Los Angeles CA, Sacramento CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18 - 70

Code: NCT05256641

Phase 1, Phase 2, Recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

for
T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma,
Location: Charlotte NC, Memphis TN, Tulsa OK, San Diego CA
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06390319

Phase 2, Recruiting

Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases

for
Breast Cancer, Triple Negative Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06238921

Phase 1, Phase 2, Recruiting

Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma

for
Oropharyngeal Carcinoma,
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT03215719

Phase 2, Recruiting

Rectal Cancer Shared Care

for
Rectal Cancer, Low Anterior Resection Syndrome
Location: Montreal
Sponsor: Jewish General Hospital

Sex: All

Age: 18+

Code: NCT04966819

Recruiting

Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

for
HR+/HER2-negative Breast Cancer, Metastatic Breast Cancer
Location: Hershey PA, Miami FL, Cleveland OH, Ypsilanti MI,
Sponsor: SynDevRx, Inc.

Sex: All

Age: 18+

Code: NCT05455619

Phase 1, Phase 2, Recruiting

Empathic Communication Skills (ECS) Training

for
Lung Cancer
Location: New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT05456841

Recruiting

Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas

for
Glioblastoma
Location: Baltimore MD, Washington DC
Sponsor: SignPath Pharma, Inc.

Sex: All

Age: 18+

Code: NCT05768919

Phase 1, Phase 2, Recruiting

Simple Bone Cysts in Kids

for
Bone Cyst
Location: Halifax, Ottawa, Chapel Hill NC, Toronto, London,
Sponsor: The Hospital for Sick Children

Sex: All

Age: 2 - 21

Code: NCT02193841

Phase 3, Recruiting

Liver Transplantation for Unresectable Liver Limited Colorectal Metastases

for
Unresectable Liver-limited Colorectal Metastases
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18 - 65

Code: NCT04742621

Recruiting
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A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia
Location: Providence RI, Worcester MA, New Haven CT, New York NY,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06428019

Phase 3, Recruiting

A Study of Sacituzumab Govitecan in People With Mesothelioma

for
Mesothelioma, Mesotheliomas Pleural, Mesothelioma; Pleura
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06477419

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer