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Oncology Clinical Trials

Browse 9,276 oncology clinical trials enrolling across the United States and Canada. 219 people applied to oncology studies last month. Search by city or state to find one near you.

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Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma

for
Renal Cell Carcinoma
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT05733715

Early Phase 1, Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

for
Relapsed or Refractory Multiple Myeloma,
Location: New York NY, Philadelphia PA, Charlotte NC, Houston TX,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05652335

Phase 1, Recruiting

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

for
Primary Immunodeficiency (PID),
Location: Pittsburgh PA
Sponsor: Paul Szabolcs

Sex: All

Age: 0 - 55

Code: NCT01962415

Phase 2, Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for
Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung
Location: Philadelphia PA, Fairfax VA, Dallas TX,
Sponsor: Lantern Pharma Inc.

Sex: All

Age: 18+

Code: NCT05456256

Phase 2, Recruiting

Characterization of the Melanoma-Specific Immune Response

for
Melanoma
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18 - 70+

Code: NCT00368615

Recruiting

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Resistance to HIV Infection

for
HIV Infections
Location: Seattle WA
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 60

Code: NCT00069485

Recruiting

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for
Myelodysplastic Syndromes
Location: Halifax, New Haven CT, Westbury NY, Columbia MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06499285

Phase 3, Recruiting

A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer

for
Surgery
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 45+

Code: NCT06312124

Recruiting

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

for
Recurrent High Grade Glioma, Anaplastic Astrocytoma,
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 19+

Code: NCT05698524

Phase 1, Recruiting

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

for
Glioma
Location: Columbus OH, Dallas TX, San Antonio TX
Sponsor: Cerenome

Sex: All

Age: 18+

Code: NCT01906385

Phase 1, Phase 2, Recruiting

Osteonecrosis in Children With Acute Lymphoblastic Leukemia

for
Osteonecrosis, Acute Lymphoblastic Leukemia
Location: Ottawa
Sponsor: Halton, Jacqueline, M.D.

Sex: All

Age: 5 - 18

Code: NCT01104324

Recruiting

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

for
Monoclonal Gammopathy of Undetermined Significance (MGUS),
Location: Boston MA, Stony Brook NY, New York NY, Philadelphia PA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06140524

Phase 2, Recruiting

Palbociclib and Pembrolizumab in Sarcoma

for
Sarcoma
Location: Iowa City IA
Sponsor: John Rieth

Sex: All

Age: 12+

Code: NCT06113809

Phase 1, Recruiting

ATRA and Carfilzomib in Plasma Cell Myeloma Patients

for
Multiple Myeloma
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT06536413

Phase 1, Phase 2, Recruiting

Alcohol and "Heat of the Moment" Sexual Decision Making

for
Alcohol Drinking, Sex, Unsafe, Hiv
Location: Boston MA
Sponsor: Boston University Charles River Campus

Sex: Male

Age: 18+

Code: NCT05729256

Recruiting

18F-Fluciclovine PET Imaging for Detecting High Grade Glioma Recurrence After Radiochemotherapy

for
Grade III or Grade IV Glioma
Location: Phoenix AZ
Sponsor: Nicole Hill

Sex: All

Age: 18+

Code: NCT05479136

Phase 3, Recruiting

An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures

for
Focal Onset Seizure, Primary Generalized Epilepsy
Location: Hackensack NJ, Middletown NY, Bethesda MD,
Sponsor: Praxis Precision Medicines

Sex: All

Age: 18 - 70+

Code: NCT06908356

Phase 2, Recruiting

Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial

for
Castration-Resistant Prostate Carcinoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male

Age: 0+

Code: NCT06288113

Phase 2, Recruiting

Use Of Indocyanine Green In Pancreas Surgery

for
Pancreatic Carcinoma
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06084013

Recruiting

Continuous Glucose Monitor Use in Pregnancy

for
Type 2 Diabetes Treated With Insulin, Pregnancy, High Risk
Location: Worcester MA
Sponsor: University of Massachusetts, Worcester

Sex: Female

Age: 18+

Code: NCT05317585

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer