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Oncology Clinical Trials

Browse 9,232 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis

for
Leptomeningeal Metastases
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05184816

Phase1, Recruiting

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

for
B-cell Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma,
Location: Montreal
Sponsor: Iksuda Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT05365659

Phase1, Recruiting

The Ambient Light Multiple Myeloma Study

for
Multiple Myeloma
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 21+

Code: NCT05737732

Recruiting

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

for
Severe Aplastic Anemia, Hypo-Plastic MDS,
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 4 - 70+

Code: NCT03173937

Phase1, Phase2, Recruiting

Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

for
Hodgkin Lymphoma
Location: Halifax, Saint John, New York NY, Ottawa, Miami FL,
Sponsor: University College, London

Sex: All

Age: 16 - 69

Code: NCT04685616

Phase3, Recruiting

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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

for
Kidney Disease, End-Stage, End-stage Renal Disease,
Location: Worcester MA, Springfield MA, West Springfield MA,
Sponsor: C. R. Bard

Sex: All

Age: 18+

Code: NCT04634916

Recruiting

Double Dose 4-AP on Functional Recovery After Spinal Cord Injury

for
SCI - Spinal Cord Injury
Location: Chicago IL
Sponsor: Shirley Ryan AbilityLab

Sex: All

Age: 18 - 70+

Code: NCT06853015

Phase1, Phase2, Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

for
Relapsed or Refractory Multiple Myeloma,
Location: New York NY, Philadelphia PA, Charlotte NC, Houston TX,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05652335

Phase1, Recruiting

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...

for
Small Cell Carcinoma of the Bladder,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06161532

Phase2, Recruiting

Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

for
Indolent B-Cell Non-Hodgkin Lymphoma,
Location: Jacksonville FL, La Crosse WI, Eau Claire WI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06386315

Phase2, Recruiting

Global Hip Dysplasia Registry

for
Hip Dislocation, Congenital,
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 0 - 10

Code: NCT04117685

Recruiting

Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple Myeloma

for
Recurrent Multiple Myeloma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06785415

Phase1, Phase2, Recruiting

A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors

for
Thymoma, Thymic Carcinoma
Location: Hackensack NJ, Washington D.C. DC, Chicago IL,
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT06248515

Phase2, Recruiting

A Feasibility Study Utilizing Immune Recall to Increase Response to Checkpoint Therapy

for
Melanoma
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT05077137

Phase1, Recruiting

A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer

for
Surgery
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 45+

Code: NCT06312124

Recruiting

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

for
Recurrent High Grade Glioma, Anaplastic Astrocytoma,
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 19+

Code: NCT05698524

Phase1, Recruiting

Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer

for
Breast Carcinoma, Invasive Breast Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05406232

Recruiting

Osteonecrosis in Children With Acute Lymphoblastic Leukemia

for
Osteonecrosis, Acute Lymphoblastic Leukemia
Location: Ottawa
Sponsor: Halton, Jacqueline, M.D.

Sex: All

Age: 5 - 18

Code: NCT01104324

Recruiting

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

for
Monoclonal Gammopathy of Undetermined Significance (MGUS),
Location: Boston MA, Stony Brook NY, New York NY, Philadelphia PA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06140524

Phase2, Recruiting

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for
Multiple Myeloma, Myeloma, Myeloma Multiple
Location: Boston MA, New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: K36 Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05651932

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer