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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 219 people applied to oncology studies last month. Search by city or state to find one near you.

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1

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

for
B-cell Acute Lymphoblastic Leukemia, Obesity
Location: Philadelphia PA, Charlotte NC, Ann Arbor MI,
Sponsor: Etan Orgel

Sex: All

Age: 7 - 25

Code: NCT05082519

Phase 2, Recruiting

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

for
Colitis, Diarrhea, Malignant Genitourinary System Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04038619

Phase 1, Recruiting

Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

for
Metastatic Melanoma, BRAF Gene Mutation
Location: Easton PA, Lexington KY, Nashville TN
Sponsor: Rina Plattner

Sex: All

Age: 18+

Code: NCT04903119

Phase 1, Recruiting

Pilot Study of PACHA Program to Enhance Adherence to Adjuvant Endocrine Therapy Among Breast Cancer Survivors

for
Breast Neoplasms, Breast Cancer
Location: Quebec city
Sponsor: CHU de Quebec-Universite Laval

Sex: All

Age: 18+

Code: NCT05887102

Recruiting

A Phase II Study Of Gliadel, Concomitant Temozolomide And Radiation, Followed By Dose Dense Therapy With Temozolomide Plus Bevacizumab For Newly Diagnosed Malignant High Grade Glioma

for
Glioma
Location: Louisville KY
Sponsor: Kentuckiana Cancer Institute

Sex: All

Age: 18 - 70+

Code: NCT00660621

Phase 2, Recruiting

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CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Duarte CA
Sponsor: Osel, Inc.

Sex: All

Age: 18+

Code: NCT06399419

Phase 1, Recruiting

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

for
Metastatic Breast Cancer, Leptomeningeal Disease
Location: Baltimore MD, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT02422641

Phase 2, Recruiting

Upright MRI for Prostate Cancer Screening

for
Prostate Cancer, Elevated PSA,
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Male

Age: 18 - 70+

Code: NCT03474913

Recruiting

Polyomic Biomarker Verification in Adult Chronic Graft-Versus-Host Disease (ABLE3.0/CTTC2201)

for
Chronic Graft-versus-Host-Disease,
Location: Toronto, Saint Louis MO, Omaha NE, Portland OR
Sponsor: University of British Columbia

Sex: All

Age: 18+

Code: NCT05692713

Recruiting

GALLANT: Metronomic Gemcitabine, Doxorubicin, Docetaxel and Nivolumab for Advanced Sarcoma

for
Sarcoma
Location: Santa Monica CA
Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All

Age: 18+

Code: NCT04535713

Phase 2, Recruiting

Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax

for
Stage 4 NSCLC, Radiotherapy
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT06262321

Phase 2, Recruiting

Parent-Delivered Massage in Paediatric Cancer

for
Anxiety, Depression, Stress, Pediatric Cancers
Location: Edmonton
Sponsor: Centennial College

Sex: All

Age: 6 - 18

Code: NCT00698113

Recruiting

Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)

for
Castrate Sensitive Prostate Cancer, Metastatic Prostate Cancer
Location: Charlottesville VA
Sponsor: Paul Viscuse

Sex: Male

Age: 18+

Code: NCT06429813

Recruiting

Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)

for
Brain Metastases
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05700721

Phase 2, Recruiting

Olanzapine 2.5 vs 5 mg in Quadruplet Nausea/Vomiting Prophylaxis Before High-Dose Melphalan

for
Multiple Myeloma, Autologous Stem Cell Transplantation
Location: Augusta GA
Sponsor: Augusta University

Sex: All

Age: 18+

Code: NCT06588413

Phase 3, Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)

for
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia,
Location: Philadelphia PA, Cincinnati OH, Chicago IL,
Sponsor: Autolus Limited

Sex: All

Age: 0 - 18

Code: NCT06173518

Phase 1, Recruiting

Cancer Pain Management Using a Web-based Intervention

for
Cancer of Breast, Depressive Symptoms, Cancer Pain
Location: Nashville TN
Sponsor: Vanderbilt University

Sex: Female

Age: 18+

Code: NCT06085313

Recruiting

Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients

for
Non-Hodgkin Lymphoma, B-cell Non-Hodgkin Lymphoma (B-NHL),
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 16+

Code: NCT05098613

Phase 1, Recruiting

Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial

for
Nodular Lymphocyte Predominant B-Cell Lymphoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05886036

Phase 2, Recruiting

Olaparib in Patients With HRD Malignant Mesothelioma

for
Mesothelioma, Homologous Recombination Deficiency
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT04515836

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer