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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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ICNBs for Post-op Pain in Breast Surgery

for
Pain, Postoperative, Length of Stay
Location: Louisville KY, New Albany IN
Sponsor: Christine M. Kleinert Institute for Hand and Microsurgery

Sex: Female

Age: 20 - 70

Code: NCT04606836

Recruiting

Preop Laxatives in Robotic Urologic Surgery

for
Prostate Cancer, Kidney Cancer, Constipation
Location: Iowa City IA
Sponsor: Chad R. Tracy

Sex: All

Age: 30 - 70+

Code: NCT05805436

Recruiting

A Non-Randomized Study of Internal Radiation Therapy to the Liver in Patients With Primary Liver Cancer for Whom Surgery is Not Possible.

for
Liver Cancer
Location: Tampa FL
Sponsor: St. Joseph's Hospital, Florida

Sex: All

Age: 18+

Code: NCT00152087

Phase2, Recruiting

DREAM: Double Lung Transplant REgistry Aimed for Lung-limited Malignancies

for
Lung Cancer, Bilateral Cancer, Lung Transplant
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18 - 70+

Code: NCT05671887

Recruiting

Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery

for
Breast Cancer
Location: Toronto
Sponsor: University of Toronto

Sex: Female

Age: 18 - 65

Code: NCT04616300

Recruiting

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Phase II Open-label Trial of Neoadjuvant Immunochemotherapy for Resectable Non-metastatic Colon cancER: NICER

for
Stage I Colon Cancer, Stage II Colon Cancer,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 18 - 70+

Code: NCT05870800

Phase2, Recruiting

Evaluation of the Efficacy and Safety of [18F]-ML-10, as a PET Imaging Radiotracer, in Early Detection of Response of Brain Metastases of Solid Tumors to Radiation Therapy.

for
Brain Metastases, Solid Tumors
Location: Boston MA, New York city NY, Pittsburgh PA
Sponsor: Aposense Ltd.

Sex: All

Age: 18+

Code: NCT00805636

Phase2, Recruiting

CAR T-cell Therapy in Patients With Renal Dysfunction

for
Non-hodgkin Lymphoma,B Cell, Multiple Myeloma,
Location: Atlanta GA
Sponsor: Northside Hospital, Inc.

Sex: All

Age: 18+

Code: NCT05909059

Phase2, Recruiting

PACIFIC: Primary Mediastinal Large B-cell Lymphoma Treated With Antibody Therapy, Checkpoint Inhibitor in Frontline With ImmunoChemotherapy

for
Ann Arbor Stage I Primary Mediastinal (Thymic) Large B-Cell Lymphoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04745949

Phase2, Recruiting

A Study of MGC028 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, NSCLC Adenocarcinoma, Cholangiocarcinoma,
Location: Boston MA, New York NY, Grand Rapids MI, San Antonio TX,
Sponsor: MacroGenics

Sex: All

Age: 18+

Code: NCT06723236

Phase1, Recruiting

Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients

for
Melanoma, Melanoma Stage III, Melanoma Stage IV,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT06199713

Recruiting

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Norwich CT, Hackensack NJ, Albany NY, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136559

Phase3, Recruiting

Efficacy & Safety for LN144 with Pembrolizumab with High Risk Stage IIIb-dResectable Melanoma

for
Stage IIIB Melanoma, Stage IIIC Melanoma, Stage IIID Melanoma
Location: Cleveland OH
Sponsor: James Isaacs, MD

Sex: All

Age: 18+

Code: NCT06190249

Phase1, Recruiting

Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML

for
Acute Monocytic Leukemia, Acute Myeloid Leukemia
Location: Miami FL, Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06504459

Phase2, Recruiting

YL-13027 in Patients With Advanced Solid Tumors

for
Solid Tumor
Location: Houston TX
Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

Sex: All

Age: 18+

Code: NCT05228600

Phase1, Recruiting

Development and Validation of Advanced MRI Methods for Clinical Applications

for
Brain Tumor
Location: Phoenix AZ
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All

Age: 18+

Code: NCT03264300

Recruiting

Magseed Enabled Long-Term Localization of Axillary Lymph Nodes

for
Breast Cancer, Axillary Lymph Nodes
Location: Houston TX
Sponsor: Endomagnetics Ltd.

Sex: All

Age: 18+

Code: NCT03796559

Recruiting

Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

for
Recurrent or Refractory Solid Tumors, Ewing Sarcoma,
Location: Cincinnati OH, Milwaukee WI, Houston TX, Dallas TX,
Sponsor: South Plains Oncology Consortium

Sex: All

Age: 1 - 20

Code: NCT02013336

Phase1, Recruiting

ECoG BMI for Motor and Speech Control

for
ALS, SCI - Spinal Cord Injury, Stroke, Multiple Sclerosis,
Location: San Francisco CA
Sponsor: Karunesh Ganguly

Sex: All

Age: 21+

Code: NCT03698149

Recruiting

Study of NRX 195183 Therapy for Patients With Relapsed or Refractory Acute Promyelocytic Leukemia

for
Acute Promyelocytic Leukemia
Location: Santa Monica, CA
Sponsor: NuRx Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT00675870

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer