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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for
Breast Cancer
Location: Boston MA, New Haven CT, Stony Brook NY, New York NY,
Sponsor: Greenwich LifeSciences, Inc.

Sex: All

Age: 18 - 70+

Code: NCT05232916

Phase 3, Recruiting

Intensive Cancer Screening After Cryptogenic Stroke

for
Occult Cancer
Location: Montreal, Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT05733416

Recruiting

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

for
AL Amyloidosis, Amyloidosis
Location: Nashville TN, Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18+

Code: NCT05145816

Phase 1, Phase 2, Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

for
Glioblastoma, High-grade Glioma, Glioblastoma, IDH-wildtype,
Location: Boston MA, San Francisco CA
Sponsor: Jasper Gerritsen

Sex: All

Age: 18 - 70+

Code: NCT06118723

Recruiting

CPRIT: Patient Adherence to Lung Cancer Screening

for
Lung Cancer Screening
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 50 - 70+

Code: NCT06872723

Recruiting

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Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

for
Diffuse Large Cell Lymphoma, Non-Hodgkin Lymphoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05389423

Phase 1, Recruiting

A Dose Study of Doxil in a Dose Dense, 14 Day CDOP/Rituximab Regimen for Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma (NHL)> 60 Years or With Compromised Cardiac Status.

for
Diffuse Large B Cell Lymphoma, Lymphoma, Non-Hodgkin
Location: Baltimore MD, Randallstown MD
Sponsor: The Alvin and Lois Lapidus Cancer Institute

Sex: All

Age: 18+

Code: NCT00333008

Phase 2, Recruiting

Improving Detection of Early Lung Cancer in a Diverse Population (IDEAL) Study

for
Lung Cancer, Pulmonary Nodule
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 50 - 70+

Code: NCT06628102

Recruiting

Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer

for
Head and Neck Cancer
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT00230308

Recruiting

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

for
HPV-Associated Oropharyngeal Squamous Cell Carcinoma,
Location: Boston MA
Sponsor: Jonathan Schoenfeld, MD, MPH

Sex: All

Age: 22+

Code: NCT04900623

Phase 2, Recruiting

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

for
Hematologic Neoplasms
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12 - 70+

Code: NCT05327023

Phase 1, Phase 2, Recruiting

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias

for
Leukemia, Lymphocytic, Chronic, B-Cell,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06364423

Phase 1, Phase 2, Recruiting

Feasibility Study of Biobehavioral Stress Reduction Intervention in Patients With Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Cleveland OH, Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female

Age: 18+

Code: NCT05677802

Recruiting

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, New Haven CT, New York NY, Burlington VT,
Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All

Age: 18+

Code: NCT06667908

Phase 2, Recruiting

CAR T Cells Targeting CD30 Positive Lymphomas (4SCAR30273)

for
Lymphomas
Location: Gainesville FL
Sponsor: Peking University

Sex: All

Age: 18+

Code: NCT02274584

Phase 1, Phase 2, Recruiting

Efficacy and Safety Study of Niraparib in Melanoma With Genetic Homologous Recombination (HR) Mutation

for
Metastatic Melanoma
Location: San Francisco CA
Sponsor: California Pacific Medical Center Research Institute

Sex: All

Age: 18+

Code: NCT03925350

Phase 2, Recruiting

Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC

for
HNSCC, Head and Neck Squamous Cell Carcinoma
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70+

Code: NCT06693323

Phase 2, Recruiting

Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal)

for
Head and Neck Carcinoma, Localized Head and Neck Carcinoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06572423

Recruiting

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: New Haven CT, Mineola NY, New York NY, Chicago IL,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05272384

Phase 1, Recruiting

Cryoablation+Ipilimumab+Nivolumab in Melanoma

for
Metastatic Melanoma, Skin Cancer
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05779423

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer