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Oncology Clinical Trials

Browse 9,232 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for
Metastatic Sarcoma, Radiation Therapy Patient, Ewing Sarcoma,
Location: Baltimore MD, Washington D.C. DC, Minneapolis MN
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 0 - 39

Code: NCT06796543

Recruiting

68Ga-PSMA PET-CT Scan for Diagnosis and Management of Prostate Cancer

for
Prostate Cancer
Location: Houston TX
Sponsor: Ebrahim Delpassand

Sex: Male

Age: 18+

Code: NCT02282137

Phase2, Recruiting

Molecular Determinants of Response to Preoperative Therapy in Patients With Locally Advanced Colorectal Cancer

for
Colorectal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02877056

Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

for
B-NHL, B-Non Hodgkin Lymphoma, Acute Lymphocytic Leukemia,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 3 - 39

Code: NCT05442515

Phase1, Phase2, Recruiting

A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: New York NY, Houston TX, Duarte CA
Sponsor: Edgewood Oncology Inc.

Sex: All

Age: 18+

Code: NCT04243785

Phase1, Recruiting

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Study of Cordycepin Plus Pentostatin in Patients With Refractory TdT-Positive Leukemia

for
Refractory TdT-Positive Leukemia
Location: Boston MA, San Antonio TX
Sponsor: OncoVista, Inc.

Sex: All

Age: 18+

Code: NCT00709215

Phase1, Phase2, Recruiting

Exercise and Relaxation Intervention for Young Adult Cancer Survivors

for
Cancer
Location: Providence RI
Sponsor: The Miriam Hospital

Sex: All

Age: 18 - 39

Code: NCT00801008

Recruiting

Iberdomide and Daratumumab as Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple Myeloma

for
Multiple Myeloma
Location: Detroit MI, Lansing MI
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 18+

Code: NCT06107738

Phase2, Recruiting

Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

for
Head and Neck Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 0+

Code: NCT04428515

Recruiting

Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases

for
Colorectal Cancer, Liver Metastases
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 68

Code: NCT02864485

Recruiting

A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

for
Breast Ductal Carcinoma In Situ
Location: Jacksonville FL, Rochester MN
Sponsor: Mayo Clinic

Sex: Female

Age: 18+

Code: NCT04144023

Phase1, Recruiting

Stereotactic Body Radiotherapy for Osseous Low Alpha-Beta Resistant Metastases for Pain Relief

for
Bone Metastases, Prostate Cancer, Breast Cancer,
Location: Hamilton
Sponsor: Hamilton Health Sciences Corporation

Sex: All

Age: 18+

Code: NCT04177056

Recruiting

PrEP Intervention in Prince George's County, Maryland

for
Hiv, Mental Health Issue, Support, Family
Location: Fairfax VA
Sponsor: George Mason University

Sex: Male

Age: 18+

Code: NCT06141408

Recruiting

Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer

for
Thyroid Gland Carcinoma, Thyroid Gland Nodule
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04742608

Recruiting

Aromatase Inhibitor Clinical Trial

for
Breast Cancer
Location: Indianapolis IN
Sponsor: National Institute of General Medical Sciences (NIGMS)

Sex: Female

Age: 40 - 70

Code: NCT00228956

Recruiting

LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors

for
Bladder Cancer, Surgery
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT04979156

Recruiting

Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia

for
Leukemia, Myelomonocytic, Chronic
Location: Tampa FL, Atlanta GA, Rochester MN, Houston TX
Sponsor: Theradex

Sex: All

Age: 18+

Code: NCT07033598

Phase2, Recruiting
New

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

for
GVHD, Hematopoietic Cell Transplantation (HCT),
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18 - 70+

Code: NCT07302776

Phase1, Recruiting

A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

for
Acute Leukemia, Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: Rochester NY, Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06207123

Phase1, Phase2, Recruiting

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT01639508

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer