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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies

for
Solid Tumor
Location: Columbus OH, West Valley City UT
Sponsor: Jabez Bioscience, Inc

Sex: All

Age: 18+

Code: NCT06801002

Phase 1, Recruiting

Study of NMS-03597812 in Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
Relapsed/Refractory Acute Myeloid Leukemia
Location: Newark DE, Canton OH, Atlanta GA, Houston TX, Aurora CO,
Sponsor: Nerviano Medical Sciences

Sex: All

Age: 18+

Code: NCT06549790

Phase 1, Recruiting

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors

for
Medulloblastoma Recurrent, Ependymoma Recurrent, ATRT Recurrent,
Location: Grand Rapids MI, Austin TX
Sponsor: Medical University of Vienna

Sex: All

Age: 0 - 19

Code: NCT01356290

Phase 2, Recruiting

A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer

for
Breast Cancer
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT06327490

Phase 2, Recruiting

Naltrexone and Propranolol Combined With Immunotherapy

for
Advanced Melanoma
Location: New Brunswick NJ
Sponsor: Sarah Weiss

Sex: All

Age: 18+

Code: NCT05968690

Phase 1, Recruiting

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Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

for
Clonal Cytopenia of Undetermined Significance,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03418038

Phase 2, Recruiting

Standard Versus Radiobiologically-Guided Dose Selected SBRT in Liver Cancer

for
Hepatocellular Carcinoma, Liver Metastases
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT04745390

Recruiting

Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers

for
Metastatic Malignant Solid Neoplasm
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06606990

Phase 1, Recruiting

Safety, Efficacy and Pharmacokinetic Study of PRLX 93936 in Patients With Multiple Myeloma

for
Multiple Myeloma
Location: Boston MA, Durham NC, Chapel Hill NC, Cincinnati OH,
Sponsor: Prolexys Pharmaceuticals

Sex: All

Age: 18+

Code: NCT01695590

Phase 1, Phase 2, Recruiting

A Clinical Study of GP73 as a Hepatocellular Carcinoma (HCC) Tumor Mark

for
Hepatocellular Carcinoma
Location: Chicago IL
Sponsor: Peking Union Medical College Hospital

Sex: All

Age: 18 - 70+

Code: NCT00902902

Recruiting

Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC

for
Head and Neck Cancer, Relapse, Recurrent, Refractory Cancer
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06096038

Phase 1, Recruiting

A Study of SBRT for Squamous Cell Carcinoma of the Head and Neck

for
Head and Neck Neoplasms, Squamous Cell Carcinoma,
Location: Hamilton
Sponsor: McMaster University

Sex: All

Age: 60+

Code: NCT04435938

Phase 2, Recruiting

Exercise Prehabilitation for Locoregional Esophageal Cancer

for
Esophageal Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06430346

Recruiting

Partial Prostate Salvage High Dose Rate Brachytherapy

for
Recurrent Prostate Cancer
Location: Kelowna
Sponsor: British Columbia Cancer Agency

Sex: Male

Age: 45+

Code: NCT03246802

Recruiting

The Cxbladder Rule-out of Recurrent Urothelial Carcinoma

for
Bladder Cancer
Location: London
Sponsor: London Health Sciences Centre

Sex: All

Age: 18+

Code: NCT03673202

Recruiting

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer,
Location: New Haven CT, Norwalk CT, New York NY, Montreal,
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All

Age: 18+

Code: NCT06343402

Phase 1, Recruiting

Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)

for
Prostate Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05043012

Recruiting

Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants

for
Head and Neck Cancer
Location: Nashville TN
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 18+

Code: NCT00898638

Recruiting

Sequencing Antibody Drug Conjugates in ER+/HER2 LOW/ULTRA LOW MBC

for
Breast Cancer, Metastatic Breast Cancer, Advanced Breast Cancer,
Location: Miami FL, Atlanta GA, Fairway KS
Sponsor: Reshma L. Mahtani, D.O.

Sex: All

Age: 18+

Code: NCT06263543

Phase 2, Recruiting

Feasibility of 18F-Fluciclovine PET/CT to Identify Brain Metastasis

for
Brain Metastases
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 18 - 70+

Code: NCT06055790

Early Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer