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Paid Clinical Trials Irvine

Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

for
Late-onset Pompe Disease
Location: Irvine CA, St Louis MO, Durham NC, Fairfax VA
Sponsor: Denali Therapeutics Inc.

Sex: All

Age: 18 - 70+

Code: NCT07354724

Phase1, Recruiting
Active & Responsive

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for
Metastatic Castration-resistant Prostate Cancer
Location: Newport Beach CA, Omaha NE, Houston TX, Metairie LA,
Sponsor: AstraZeneca

Sex: Male

Age: 18+

Code: NCT07611110

Phase3, Recruiting
Active & Responsive

Lumateperone in the Treatment of Stuttering, Childhood Onset Fluency Disorder

for
Stuttering, Adult
Location: Costa Mesa CA
Sponsor: CSTrials Inc.

Sex: All

Age: 18 - 65

Code: NCT07734103

Phase2, Recruiting
Active & Responsive

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for
Treatment Resistant Depression
Location: Costa Mesa CA, Los Angeles CA, La Jolla CA,
Sponsor: LivaNova

Sex: All

Age: 18+

Code: NCT03887715

Recruiting
Active & Responsive

KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

for
Myasthenia Gravis, Generalized Myasthenia Gravis
Location: Orange CA, Los Angeles CA, Palo Alto CA, Murray UT,
Sponsor: Kyverna Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06193889

Phase2, Phase3, Recruiting

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Active & Responsive

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Location: Orange CA, Long Beach CA, Torrance CA,
Sponsor: Cleerly, Inc.

Sex: All

Age: 55+

Code: NCT06112418

Recruiting
Active & Responsive

ASSESS ALL ALS Study

for
Amyotrophic Lateral Sclerosis
Location: Irvine CA, Los Angeles CA, La Jolla CA, Phoenix AZ,
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All

Age: 18+

Code: NCT06578195

Recruiting
Active & Responsive

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for
Heart Failure With Preserved Ejection Fraction,
Location: Orange CA, Newport Beach CA, Covina CA, Pomona CA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07037459

Phase3, Recruiting
Active & Responsive

Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

for
Breast Cancer Screening, Breast Carcinoma in Situ,
Location: Irvine CA, Los Angeles CA, San Diego CA,
Sponsor: University of California, San Francisco

Sex: Female

Age: 30 - 70+

Code: NCT02620852

Recruiting
Active & Responsive

A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis

for
Lupus Nephritis, Systemic Lupus Erythematosus,
Location: Irvine CA, Fullerton CA, Fontana CA, Beverly Hills CA,
Sponsor: Fate Therapeutics

Sex: All

Age: 12 - 70

Code: NCT07570862

Phase2, Recruiting
Active & Responsive

A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT

for
Port-wine Birthmarks, Port-Wine Stain, Nevus Flammeus
Location: Irvine CA, San Diego CA, Hunt Valley MD, Miami FL,
Sponsor: Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.

Sex: All

Age: 18 - 70+

Code: NCT05171894

Phase2, Recruiting
Active & Responsive

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Irvine CA, Huntington Beach CA, Duarte CA,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 18+

Code: NCT06043817

Phase1, Phase2, Recruiting
Active & Responsive

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Irvine CA, Duarte CA, Santa Fe NM, Houston TX,
Sponsor: Xerient Pharma

Sex: All

Age: 18+

Code: NCT07157033

Phase1, Phase2, Recruiting
Active & Responsive

Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for
Weight Regain, Weight Loss
Location: Irvine CA, Stanford CA, Houston TX, Rochester MN,
Sponsor: Boston Scientific Corporation

Sex: All

Age: 18+

Code: NCT07015424

Recruiting
Active & Responsive

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Castration Resistant Metastatic Prostate Cancer,
Location: Irvine CA, Omaha NE, Kansas City KS, Grand Rapids MI,
Sponsor: Aktis Oncology, Inc.

Sex: Male

Age: 18+

Code: NCT07581184

Phase1, Recruiting
Active & Responsive

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Irvine CA, Anaheim CA, Bellflower CA, Riverside CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase2, Phase3, Recruiting
Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Irvine CA, Orange CA, Duarte CA, Scottsdale AZ,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting
Active & Responsive

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for
Plaque Psoriasis
Location: Santa Ana CA, Fountain Valley CA, Los Angeles CA,
Sponsor: Oruka Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07449702

Phase2, Recruiting
Active & Responsive

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for
Macular Degeneration, Age-Related Macular Degeneration,
Location: Santa Ana CA, Encino CA, Mountain View CA, Gilbert AZ,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 50+

Code: NCT07496567

Phase2, Phase3, Recruiting
Active & Responsive

ACP-204 in Adults With Alzheimer's Disease Psychosis

for
Alzheimer's Disease Psychosis
Location: Costa Mesa CA, Fresno CA, Scottsdale AZ, Chandler AZ,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 55 - 70+

Code: NCT06159673

Phase2, Phase3, Recruiting