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Paid Clinical Trials Irvine

Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy

for
Diabetic Retinopathy
Location: Glendale CA, Oak Forest IL, Columbus OH
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07588100

Phase1, Recruiting
Featured

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

for
Primary Open Angle Glaucoma
Location: Culver City CA, Glendale AZ, Petaluma CA, El Paso TX,
Sponsor: AbbVie

Sex: All

Age: 45+

Code: NCT06822738

Phase3, Recruiting
Featured

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

for
Diabetic Macular Edema
Location: Beverly Hills CA, Peoria AZ, Walnut Creek CA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07425522

Phase1, Recruiting
Featured

A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

for
Multiple Myeloma
Location: Los Angeles CA, Scottsdale AZ, Eugene OR, Denver CO,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07095452

Phase2, Phase3, Recruiting
Featured

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for
Non-Small Cell Lung Cancer
Location: Los Angeles CA, Oxnard CA, Chandler AZ, Reno NV,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06568939

Phase2, Recruiting

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Featured

A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-Resistant Prostate Cancer
Location: Los Angeles CA, San Francisco CA, Iowa City IA, Toronto,
Sponsor: Hoffmann-La Roche

Sex: Male

Age: 18+

Code: NCT07287150

Phase2, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Los Angeles CA, San Diego CA, San Francisco CA, Reno NV,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
Active & Responsive

A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)

for
Atopic Dermatitis
Location: Irvine CA, New York NY, The Bronx NY
Sponsor: Bambusa Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06808477

Phase1, Recruiting
Active & Responsive

Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)

for
ADHD
Location: Irvine CA, Long Beach CA, Los Angeles CA, Las Vegas NV,
Sponsor: Axsome Therapeutics, Inc.

Sex: All

Age: 12 - 17

Code: NCT07717892

Phase3, Recruiting
Active & Responsive

Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-2)

for
ADHD
Location: Irvine CA, Orange CA, Long Beach CA, Las Vegas NV,
Sponsor: Axsome Therapeutics, Inc.

Sex: All

Age: 6 - 11

Code: NCT07717879

Phase3, Recruiting
Active & Responsive

A Study of RSLV-132 in Females With Sjögren's Disease

for
Primary Sjögren Syndrome
Location: Tustin CA, Chula Vista CA, Salt Lake City UT,
Sponsor: Resolve Therapeutics

Sex: Female

Age: 18 - 70+

Code: NCT06440525

Phase2, Recruiting
Active & Responsive

Effect of Amnio-Maxx on the Healing Rate of Chronic Diabetic Foot Ulcers.

for
Diabetic Foot Ulcer (DFU), Amnio-Maxx
Location: Burbank CA, Spicewood TX, Carrollton TX, Tulsa OK,
Sponsor: Royal Biologics

Sex: All

Age: 18+

Code: NCT07209475

Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Irvine CA, Orange CA, Los Angeles CA, Beverly Hills CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase2, Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Irvine CA, Orange CA, Anaheim CA, Bellflower CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase2, Recruiting
Active & Responsive

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

for
Unresectable or Metastatic Hepatocellular Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Peoria IL,
Sponsor: CatalYm GmbH

Sex: All

Age: 18 - 70+

Code: NCT07219459

Phase2, Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

for
Obesity, Overweight and/or Obesity, Overweight
Location: Tustin CA, Canoga Park CA, Escondido CA, West Hills CA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07595549

Phase3, Recruiting
Active & Responsive

A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)

for
Urinary Tract Infections
Location: Tustin CA, Murrieta CA, Los Angeles CA, San Diego CA,
Sponsor: Locus Biosciences

Sex: Female

Age: 18 - 70+

Code: NCT05488340

Phase2, Recruiting
Active & Responsive

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

for
Obesity, Overweight
Location: Tustin CA, Santa Ana CA, Fountain Valley CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07321886

Phase3, Recruiting
Active & Responsive

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

for
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Location: Irvine CA, Torrance CA, Roseville CA, Tucson AZ,
Sponsor: Eli Lilly and Company

Sex: All

Age: 12+

Code: NCT06338995

Phase3, Recruiting
Active & Responsive

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for
Acute Ischemic Stroke
Location: Irvine CA, Pomona CA, Glendale CA, San Francisco CA,
Sponsor: Mercy Health Ohio

Sex: All

Age: 18 - 70+

Code: NCT05611242

Phase3, Recruiting