Discover 125 paid clinical trials in Springfield, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Springfield is home to a wide range of medical studies focused on various conditions such as multiple sclerosis, cardiovascular disease, leukemia, and lymphoma. Healthy volunteers looking for paid opportunities, as well as those in need of a clinical trial for a specific health condition, have the opportunity to participate in innovative research and access the latest medical treatments.
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Results: 125
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
for
Fibromyalgia
Location: Springfield MO, Overland Park KS, Kansas City KS,
Sponsor: Axsome Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT07398417
Phase3, Recruiting
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
for
Chronic Idiopathic Constipation (CIC)
Location: Springfield MO, Columbia Falls MT, Overland Park KS,
Sponsor: Ardelyx
Sex: All
Age: 18 - 70+
Code: NCT07382167
Phase3, Recruiting
AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer
for
Epithelial Ovarian Cancer
Location: Springfield MO, Germantown TN, Peoria IL, Omaha NE,
Sponsor: AstraZeneca
Sex: Female
Age: 18+
Code: NCT07218809
Phase3, Recruiting
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
for
Metastatic Colorectal Cancer (CRC)
Location: Springfield MO, Westwood KS, O'Fallon IL, Germantown TN,
Sponsor: Summit Therapeutics
Sex: All
Age: 18+
Code: NCT07228832
Phase3, Recruiting
A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients
for
Untreated Follicular Lymphoma
Location: Springfield MO, Huntsville AL, Fort Wayne IN, Macon GA,
Sponsor: AstraZeneca
Sex: All
Age: 18 - 70+
Code: NCT06549595
Phase3, Recruiting
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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
for
Cardiovascular Disease
Location: Springfield MO, Jefferson City MO, Kansas City MO,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT07000357
Phase3, Recruiting
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
for
Advanced Breast Cancer
Location: Springfield MO, Saint Joseph MO, Urbana IL,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT06380751
Phase3, Recruiting
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
for
Endometrial Cancer
Location: Springfield MO, Little Rock AR, St Louis MO,
Sponsor: AstraZeneca
Sex: Female
Age: 18+
Code: NCT06989112
Phase3, Recruiting
A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing
Location: Springfield MO, Atlamonte Springs FL, Port Charlotte FL
Sponsor: novoGI
Sex: All
Age: 18+
Code: NCT01880918
Recruiting
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
for
Hormone Receptor Positive HER-2 Negative Breast Cancer,
Location: Springfield MO, Columbia MO, Kansas City MO,
Sponsor: Puma Biotechnology, Inc.
Sex: All
Age: 18+
Code: NCT06369285
Phase2, Recruiting
TEMPUS ARIES: A Biobank Registry Platform Study in Oncology
for
Cancer
Location: Springfield MO, Osage Beach MO, Hannibal MO,
Sponsor: Tempus AI
Sex: All
Age: 18 - 70+
Code: NCT06207032
Recruiting
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
for
Head and Neck Squamous Cell Carcinoma
Location: Springfield MO, Westwood KS, St Louis MO, Decatur IL,
Sponsor: Tempus AI
Sex: All
Age: 18+
Code: NCT06163534
Recruiting
Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
for
Breast Cancer, TNBC - Triple-Negative Breast Cancer,
Location: Springfield MO, O'Fallon IL, Carbondale IL,
Sponsor: Tempus AI
Sex: All
Age: 18 - 70+
Code: NCT07211178
Recruiting
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
for
Large B-cell Lymphoma
Location: Springfield MO, Columbia MO, Kansas City MO,
Sponsor: Allogene Therapeutics
Sex: All
Age: 18+
Code: NCT06500273
Phase2, Recruiting
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
for
Carcinoma, Non-Small-Cell Lung
Location: Springfield MO, Fairway KS, Kansas City MO, St Louis MO,
Sponsor: Janssen Research & Development, LLC
Sex: All
Age: 18+
Code: NCT06667076
Phase2, Recruiting
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Location: Springfield MO, St Louis MO, Tyler TX, Dallas TX,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT07218380
Phase3, Recruiting
BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease
for
HR+/HER2- Breast Cancer
Location: Springfield MO, Hot Springs AR, OFallon IL, Lincoln NE,
Sponsor: BeOne Medicines
Sex: All
Age: 18+
Code: NCT07492641
Phase3, Recruiting
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
for
Breast Neoplasms, Neoplasm Metastasis
Location: Springfield MO, Springdale AR, Tupelo MS, Dallas TX,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT07174336
Phase3, Recruiting
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
for
CLL, Chronic Lymphocytic Leukemia
Location: Springfield MO, Jonesboro AR, Chesterfield MO, Omaha NE,
Sponsor: BeOne Medicines
Sex: All
Age: 18+
Code: NCT06846671
Phase3, Recruiting
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
for
CRC (Colorectal Cancer)
Location: Springfield MO, Columbia MO, Kansas City MO,