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Paid Clinical Trials Springfield

Discover 125 paid clinical trials in Springfield, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for
Obesity, Overweight, Osteoarthritis, Knee
Location: Springfield MO, Dallas TX, Louisville KY, Skokie IL,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18+

Code: NCT07509307

Phase3, Recruiting
Active & Responsive

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

for
Obesity, Overweight
Location: Springfield MO, City of Saint Peters MO, Topeka KS,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06143956

Phase2, Recruiting

Comparison of Immediate Changes in Cervical Range of Motion Following Cervical Extension and Downslip Mobilizations.

for
Cervical Disease
Location: Springfield MO
Sponsor: Missouri State University

Sex: All

Age: 18 - 45

Code: NCT07656285

Recruiting

A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH

for
Non-alcoholic Fatty Liver Disease
Location: Springfield MO, Topeka KS, St Louis MO, Dallas TX,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70+

Code: NCT07221188

Phase3, Recruiting

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

for
Non-alcoholic Fatty Liver Disease
Location: Springfield MO, Kansas City MO, Little Rock AR,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70+

Code: NCT07221227

Phase3, Recruiting

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for
Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma,
Location: Springfield MO, Kansas City KS, Hot Springs AR,
Sponsor: Sameek Roychowdhury

Sex: All

Age: 18+

Code: NCT06906562

Phase2, Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Fort Smith AR, Olathe KS, Overland Park KS, Westwood KS,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06058377

Phase3, Recruiting

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for
Fallopian Tube Endometrioid Adenocarcinoma,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06580314

Phase3, Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for
Non-small Cell Lung Cancer
Location: Springfield MO, Kansas City MO, Skokie IL, Madison WI,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06345729

Phase3, Recruiting

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

for
Ovarian Neoplasms, Fallopian Tube Neoplasms,
Location: Springfield MO, Columbia MO, Peoria IL, Shreveport LA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07213804

Phase3, Recruiting
New

A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults

for
Pneumococcal Disease
Location: Springfield MO, Chesterfield MO, St Louis MO,
Sponsor: Pfizer

Sex: All

Age: 18 - 49

Code: NCT07794748

Phase3, Recruiting

Study Will Assess Skin Irritation and Sensitization for HP-1050 Patch

for
Cumulative Irritation and Sensitization
Location: Springfield MO
Sponsor: Noven Pharmaceuticals, Inc.

Sex: Female

Age: 18 - 35

Code: NCT04624867

Phase1, Recruiting

Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

for
Normal and Diseased Tissue and Body Fluids Samples
Location: Springfield MO, Tulsa OK, Memphis TN, Peoria IL,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT01354002

Recruiting
New

Sacituzumab Govitecan With Bevacizumab Compared to Usual Chemotherapy (Carboplatin, Pegylated Liposomal Doxorubicin and Bevacizumab) for Treating Recurrent Platinum-Sensitive Ovarian Cancer After PARP Inhibitor Maintenance Therapy

for
Recurrent Platinum-Sensitive Fallopian Tube Endometrioid Adenocarcinoma,
Location: Springfield MO, Rogers AR, Springdale AR,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07504588

Phase2, Recruiting

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

for
Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Location: Springfield MO, Oklahoma City OK, Omaha NE,
Sponsor: NRG Oncology

Sex: Female

Age: 18+

Code: NCT05646316

Phase3, Recruiting

Galleri® in the Medicare Population.

for
Cancer
Location: Springfield MO, Fort Smith AR, St Louis MO,
Sponsor: GRAIL, Inc.

Sex: All

Age: 50+

Code: NCT05673018

Recruiting

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Springfield MO, Lee's Summit MO, Overland Park KS,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06500481

Phase3, Recruiting

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for
Advanced Colorectal Carcinoma,
Location: Springfield MO, Osage Beach MO, Sullivan MO,
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT06073431

Recruiting

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

for
Advanced Extrapulmonary Neuroendocrine Carcinoma,
Location: Springfield MO, Joplin MO, St Louis MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05058651

Phase2, Phase3, Recruiting

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

for
Malignant Digestive System Neoplasm,
Location: Springfield MO, Branson MO, Joplin MO, Osage Beach MO,
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT07215624

Recruiting