Discover 125 paid clinical trials in Springfield, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Springfield is home to a wide range of medical studies focused on various conditions such as multiple sclerosis, cardiovascular disease, leukemia, and lymphoma. Healthy volunteers looking for paid opportunities, as well as those in need of a clinical trial for a specific health condition, have the opportunity to participate in innovative research and access the latest medical treatments.
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Results: 125
Featured
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
for
Non Small Cell Lung Cancer
Location: Springfield MO, Kansas City MO, Hattiesburg MS,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT04928846
Phase3, Recruiting
Featured
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Springfield MO, St Louis MO, Peoria IL, Shreveport LA,
Sponsor: AbbVie
Sex: Female
Age: 18+
Code: NCT06890338
Phase2, Recruiting
Featured
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
for
Obesity or Overweight
Location: Springfield MO, Tulsa OK, Clarksville TN, Dallas TX,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT07351045
Phase3, Recruiting
Active & Responsive
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: SWOG Cancer Research Network
Sex: All
Age: 18+
Code: NCT05929768
Phase3, Recruiting
Active & Responsive
A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001).
for
Healthy
Location: Springfield MO, Kansas City MO, Oklahoma City OK,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 12 - 30
Code: NCT06655324
Phase1, Recruiting
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Active & Responsive
A Study of V132 in Healthy Older Participants (V132-001)
for
Healthy
Location: Springfield MO, Lincoln NE, Omaha NE, League City TX,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 50 - 70+
Code: NCT07712575
Phase1, Recruiting
Active & Responsive
A Study of V118E in Healthy Participants (V118E-003)
for
Healthy
Location: Springfield MO, Hallandale FL
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18 - 49
Code: NCT07168915
Phase1, Recruiting
Active & Responsive
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
Location: Springfield MO, Rogers AR, Springdale AR,
Sponsor: National Cancer Institute (NCI)
Sex: Female
Age: 18+
Code: NCT07198074
Phase3, Recruiting
Active & Responsive
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
for
Colorectal Cancer Stage II, Colorectal Cancer Stage III
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: SWOG Cancer Research Network
Sex: All
Age: 18+
Code: NCT07018869
Phase3, Recruiting
Active & Responsive
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
for
Plasma Cell Myeloma
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: SWOG Cancer Research Network
Sex: All
Age: 0+
Code: NCT05561387
Phase3, Recruiting
Active & Responsive
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
for
Ampulla of Vater Carcinoma, Appendix Carcinoma,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 18+
Code: NCT07283939
Recruiting
Active & Responsive
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Location: Springfield MO, Hannibal MO, Oklahoma City OK, Omaha NE,
Sponsor: Tempus AI
Sex: All
Age: 18+
Code: NCT06911632
Recruiting
Active & Responsive
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All
Age: 18+
Code: NCT07091617
Recruiting
Active & Responsive
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
for
Pulmonary Nodule, Solitary, Lung Cancer
Location: Springfield MO, Kansas City MO, Kansas City KS,
Sponsor: Veracyte, Inc.
Sex: All
Age: 29 - 70+
Code: NCT06426628
Recruiting
Active & Responsive
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
for
Colorectal Cancer
Location: Springfield MO, Joplin MO, Fort Smith AR,
Sponsor: Tempus AI
Sex: All
Age: 18+
Code: NCT05234177
Recruiting
Active & Responsive
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)
for
Left-sided Colorectal Cancer
Location: Springfield MO, Indianapolis IN, Warner Robins GA,
Sponsor: Genmab
Sex: All
Age: 18+
Code: NCT07702032
Phase3, Recruiting
Active & Responsive
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
for
Overweight, Obesity
Location: Springfield MO, City of Saint Peters MO, Topeka KS,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18 - 70+
Code: NCT07589608
Phase2, Recruiting
Active & Responsive
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain
for
Diabetic Peripheral Neuropathic Pain
Location: Springfield MO, Tulsa OK, City of Saint Peters MO,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT07285018
Phase2, Recruiting
Active & Responsive
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
for
Osteoarthritis, Knee, Diabetic Neuropathic Pain,
Location: Springfield MO, Tulsa OK, City of Saint Peters MO,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT05986292
Phase2, Recruiting
Active & Responsive
A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine
for
Menstrual Migraine
Location: Springfield MO, Weldon Spring MO, Papillion NE,