Paid Clinical Trials Springfield

Discover 184 paid clinical trials in Springfield, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Results: 184

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Recruiting

PHASE3

Sponsor:

AbbVie

Location:

Springfield, Kansas City, Jonesboro, Oklahoma Cityshow 74 more

Code:

NCT05814627

Conditions

Rheumatoid Arthritis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Upadacitinib

Adalimumab

Upadacitinib Matching Placebo

Adalimumab Matching Placebo

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Recruiting

PHASE3

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Bolivar, Joplin, Rollashow 395 more

Code:

NCT04181060

Conditions

Advanced Lung Non-Squamous Non-Small Cell Carcinoma

Metastatic Lung Non-Squamous Non-Small Cell Carcinoma

Recurrent Lung Non-Squamous Non-Small Cell Carcinoma

Stage IIIB Lung Cancer AJCC v8

Stage IV Lung Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Bevacizumab

Biospecimen Collection

Computed Tomography

Echocardiography

Magnetic Resonance Imaging

MILD® Percutaneous Image-Guided Lumbar Decompression: a Medicare Claims Study

Recruiting

Sponsor:

Vertos Medical, Inc.

Location:

Springfield, Bolivar, Carthage, Rogersshow 944 more

Code:

NCT03072927

Conditions

Lumbar Spinal Stenosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MILD

Interspinous Process Decompression

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Recruiting

PHASE3

Sponsor:

Sanofi

Location:

Ozark, Overland Park, Kansas City, Saint Louisshow 78 more

Code:

NCT06141473

Conditions

Multiple Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Interventions

Frexalimab

Teriflunomide

Placebo infusion

Placebo tablet

MRI contrast-enhancing agents

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Recruiting

PHASE3

Sponsor:

BeiGene

Location:

Springfield, Columbia, Topeka, Wichitashow 61 more

Code:

NCT05100862

Conditions

Relapsed/Refractory Follicular Lymphoma

Marginal Zone Lymphoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Zanubrutinib

Rituximab

Lenalidomide

Obinutuzumab

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

Recruiting

Sponsor:

Wake Forest University Health Sciences

Location:

Springfield, Joplin, Osage Beach, Rollashow 190 more

Code:

NCT06216574

Conditions

Breast Cancer Female

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Internet-based Intervention

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Recruiting

PHASE3

Sponsor:

Eli Lilly and Company

Location:

Springfield, Kansas City, Little Rock, Wichitashow 73 more

Code:

NCT04396574

Conditions

Migraine

Eligibility Criteria

Sex: All

Age: 6 - 17

Healthy Volunteers: Not accepted

Interventions

Lasmiditan

Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment

Recruiting

PHASE3

Sponsor:

Boehringer Ingelheim

Location:

Springfield, Bridgeton, Nashville, Irvingshow 17 more

Code:

NCT06151574

Conditions

Lung Cancer, Non-squamous, Non-small Cell

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

zongertinib

pembrolizumab

cisplatin

carboplatin

pemetrexed

Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Bolivar, Branson, Joplinshow 244 more

Code:

NCT04164082

Conditions

Bladder Urothelial Carcinoma In Situ

Non-Muscle Invasive Bladder Urothelial Carcinoma

Stage 0a Bladder Cancer AJCC v8

Stage 0is Bladder Cancer AJCC v8

Stage I Bladder Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biopsy

Biospecimen Collection

Computed Tomography

Cystoscopy

Gemcitabine Hydrochloride

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

Recruiting

Sponsor:

PrECOG, LLC.

Location:

Springfield, Joplin, Rolla, Fort Smithshow 28 more

Code:

NCT06538038

Conditions

Non Small Cell Lung Cancer

Epidermal Growth Factor Receptor Gene Mutation

Stage III Lung Cancer

Stage IV Lung Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Osimertinib

Osimertinib + Chemotherapy