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Paid Clinical Trials Springfield

Discover 125 paid clinical trials in Springfield, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Springfield MO, Lee's Summit MO, Overland Park KS,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase3, Recruiting

Family Communications After Genetic Testing

for
Colon Adenocarcinoma, Colorectal Adenocarcinoma,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07143487

Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Springfield MO, Bolivar MO, Joplin MO, Osage Beach MO,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07097142

Phase3, Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

for
Cancer, Immunotherapy, Advanced Solid Tumors Cancer,
Location: Springfield MO, Fort Smith AR, St Louis MO,
Sponsor: Elephas

Sex: All

Age: 18+

Code: NCT07327489

Recruiting

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Springfield MO, Joplin MO, Rogers AR, Springdale AR,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase3, Recruiting

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E-Mindfulness Approaches for Living After Breast Cancer

for
Breast Cancer, Depression
Location: Springfield MO, Osage Beach MO, Fort Smith AR,
Sponsor: NRG Oncology

Sex: All

Age: 18 - 50

Code: NCT06748222

Phase3, Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for
Advanced Malignant Solid Neoplasm,
Location: Springfield MO, Rolla MO, Sullivan MO, Farmington MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT05564377

Phase2, Recruiting

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for
Metastatic Clear Cell Renal Cell Carcinoma,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04510597

Phase3, Recruiting

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

for
Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT04566328

Phase3, Recruiting

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for
Biochemically Recurrent Prostate Carcinoma,
Location: Springfield MO, Bolivar MO, Joplin MO, Osage Beach MO,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male

Age: 18+

Code: NCT04423211

Phase3, Recruiting

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for
Cardiotoxicity, HER2/Neu Positive,
Location: Springfield MO, Jefferson City MO, Lee's Summit MO,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT03418961

Phase3, Recruiting

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for
Ovarian Carcinoma
Location: Springfield MO, Overland Park KS, Westwood KS,
Sponsor: NRG Oncology

Sex: Female

Age: 35 - 50

Code: NCT04251052

Recruiting

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for
Acral Lentiginous Melanoma,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT04511013

Phase2, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for
Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8,
Location: Springfield MO, Rolla MO, Lee's Summit MO, Olathe KS,
Sponsor: NRG Oncology

Sex: Male

Age: 18+

Code: NCT05946213

Phase3, Recruiting

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Springfield MO, Bolivar MO, Branson MO, Joplin MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03191149

Phase2, Recruiting

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for
Intracranial Meningioma, Recurrent Meningioma,
Location: Springfield MO, Branson MO, Joplin MO, Osage Beach MO,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT02523014

Phase2, Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for
Metastatic Renal Cell Carcinoma,
Location: Springfield MO, Columbia MO, Tulsa OK, Little Rock AR,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05327686

Phase2, Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Springfield MO, Rogers AR, Springdale AR,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05987241

Phase2, Phase3, Recruiting

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

for
Pancreatic Acinar Cell Carcinoma,
Location: Springfield MO, Pittsburg KS, Lee's Summit MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04858334

Phase2, Recruiting

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for
Intracerebral Hemorrhage, Atrial Fibrillation
Location: Springfield MO, Columbia MO, Kansas City KS, Tulsa OK,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT03907046

Phase3, Recruiting