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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for
Myelofibrosis, Post-PV MF, Post-ET Myelofibrosis,
Location: Charlotte NC, Winston-Salem NC, Durham NC, Wilson NC,
Sponsor: Kartos Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06479135

Phase3, Recruiting

A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Charlotte NC, Louisville KY, Columbus OH, Baltimore MD,
Sponsor: Regeneron Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT05125016

Phase1, Phase2, Recruiting

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

for
High-Risk Non-Muscle-Invasive Bladder Cancer
Location: Charlotte NC, Lisle IL, Chapel Hill NC, Raleigh NC,
Sponsor: CG Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06567743

Phase2, Recruiting

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

for
Mantle Cell Lymphoma, B Cell Lymphoma
Location: Charlotte NC, Winston-Salem NC, Durham NC,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06742996

Phase3, Recruiting

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for
Triple-Negative Breast Cancer
Location: Charlotte NC, Fayetteville NC, Midlothian VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06393374

Phase3, Recruiting

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JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

for
Carcinoma, Squamous Cell
Location: Charlotte NC, Chapel Hill NC, Atlanta GA,
Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All

Age: 60+

Code: NCT04892173

Phase3, Recruiting

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for
Graft-versus-host Disease (GVHD)
Location: Charlotte NC, Chapel Hill NC, Durham NC, Charleston SC,
Sponsor: Incyte Corporation

Sex: All

Age: 18+

Code: NCT06615050

Phase3, Recruiting

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

for
Hematological Malignancy, Solid Tumor Malignancy
Location: Charlotte NC, Cincinnati OH, Baltimore MD, Seattle WA
Sponsor: Century Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05768269

Recruiting

X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

for
Advanced Solid Tumor Cancer
Location: Charlotte NC, Greenville SC, Durham NC,
Sponsor: Immunolight, LLC

Sex: All

Age: 18+

Code: NCT04389281

Phase1, Recruiting

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

for
Multiple Myeloma
Location: Charlotte NC, Atlanta GA, Nashville TN, Pittsburgh PA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05201781

Recruiting

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

for
Non-small Cell Lung Cancer
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06567704

Recruiting

Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

for
Cancer, Fatigue
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06634381

Recruiting

Digoxin Medulloblastoma Study

for
Medulloblastoma, Medulloblastoma, Non-WNT/Non-SHH
Location: Charlotte NC, Chapel Hill NC, Lexington KY,
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 1 - 30

Code: NCT06701812

Phase2, Recruiting

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

for
Pediatric Sarcoma, Refractory, Pediatric Sarcoma, Relapsed
Location: Charlotte NC, Chapel Hill NC, Durham NC, Nashville TN,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 2 - 40

Code: NCT05634369

Phase1, Phase2, Recruiting

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for
Neoplasms
Location: Charlotte NC, Greenville SC, Atlanta GA, Nashville TN,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06150157

Phase1, Recruiting

Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

for
Pancreas Adenocarcinoma,
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT05825066

Phase2, Recruiting

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

for
Prostatic Neoplasms
Location: Charlotte NC, Atlanta GA, Nashville TN, Philadelphia PA,
Sponsor: Janssen Research & Development, LLC

Sex: Male

Age: 18+

Code: NCT06095089

Phase1, Recruiting

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Charlotte NC, Fairfax VA, Washington D.C. DC,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05118789

Phase1, Phase2, Recruiting

Study of SGR-3515 In Participants With Advanced Solid Tumors.

for
Advanced Solid Tumor
Location: Charlotte NC, Fairfax VA, Cincinnati OH, Nashville TN,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT06463340

Phase1, Recruiting

Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma

for
Pancreas Adenocarcinoma, Cachexia
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT05376592

Recruiting