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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

for
Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Location: Charlotte NC, Kansas City KS, Minneapolis MN, Duarte CA,
Sponsor: PeproMene Bio, Inc.

Sex: All

Age: 18+

Code: NCT05370430

Phase1, Recruiting

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

for
Non-Muscle Invasive Bladder Cancer
Location: Charlotte NC, Raleigh NC, Myrtle Beach SC, Knoxville TN,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06319820

Phase3, Recruiting

Evaluation of the Pathobiology of CALR-mutated MPN Cells

for
Myeloproliferative Neoplasm
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06480591

Recruiting

Quick Start Durvalumab Following Chemoradiation for Stage III Nonsmall Cell Lung Cancer

for
Nonsmall Cell Lung Cancer Stage III,
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT05696782

Phase2, Recruiting

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

for
Accelerated Phase Myeloproliferative Neoplasm,
Location: Charlotte NC, Concord NC, Richmond VA, Nashville TN,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06661915

Phase2, Recruiting

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Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for
Astrocytoma, IDH-Mutant, Grade 2,
Location: Charlotte NC, Winston-Salem NC, Atlanta GA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06860594

Phase1, Recruiting

Utility of a Mobile Application for Young Women With Breast Cancer

for
Breast Cancer, Cancer Distress
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: Female

Age: 18 - 45

Code: NCT07009093

Recruiting

Comprehensive Care for AYA: Needs Assessment Survey

for
Cancer, Young Adult Cancer, Adolescent Cancer
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 15+

Code: NCT07196241

Recruiting

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

for
Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia
Location: Charlotte NC, Gastonia NC, Monroe NC, Clinton NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04840602

Phase2, Recruiting

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

for
Follicular Lymphoma (FL)
Location: Charlotte NC, Chapel Hill NC, Charlottesville VA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06091254

Phase3, Recruiting

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for
Chronic Lymphocytic Leukemia
Location: Charlotte NC, Durham NC, Jacksonville FL, Pittsburgh PA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07277231

Phase3, Recruiting

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

for
Sarcoma Metastatic, Sarcoma, Soft Tissue
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT07291297

Phase2, Recruiting

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Charlotte NC, Boiling Springs SC, Winston-Salem NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06672146

Phase2, Recruiting

ONC-MM-2407: The Effect of Virtual Reality Headsets on Pain and Anxiety in the Peri and Post Bone Marrow Biopsy Period

for
Hematologic Malignancy
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT07203534

Recruiting

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

for
Chronic Graft-versus-host-disease
Location: Charlotte NC, Atlanta GA, Washington D.C. DC,
Sponsor: Incyte Corporation

Sex: All

Age: 2 - 17

Code: NCT07124078

Phase2, Recruiting

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Charlotte NC, Concord NC, Chapel Hill NC, Charleston SC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07195734

Phase2, Recruiting

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

for
Endometrial Cancer, Recurrent or Progressive Endometrial Cancer
Location: Charlotte NC, Gastonia NC, Concord NC, Winston-Salem NC,
Sponsor: Genmab

Sex: Female

Age: 18+

Code: NCT07166094

Phase3, Recruiting

R.E.C.K vs Exparel in Robotic Nephrectomy

for
Renal Carcinoma, Nephrectomy / Methods, Pain Management
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT07092566

Phase3, Recruiting

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06973187

Phase3, Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for
Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma
Location: Charlotte NC, Chapel Hill NC, Hillsborough NC,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06989437

Phase2, Phase3, Recruiting