Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Charlotte offers many opportunities to participate in clinical research focused on various conditions, including cancer, lymphoma, heart disease, and cystic fibrosis. The city’s medical research institutions are recruiting both healthy volunteers interested in paid trials, as well as individuals with specific health conditions.
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Results: 644
A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma
for
Relapsed or Refractory Multiple Myeloma
Location: Charlotte NC, Atlanta GA, Nashville TN, Birmingham AL,
Sponsor: ModernaTX, Inc.
Sex: All
Age: 18+
Code: NCT07116616
Phase1, Phase2, Recruiting
Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer
for
Gynecologycal Cancer
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences
Sex: Female
Age: 50+
Code: NCT07046936
Recruiting
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
for
HER2-positive Breast Cancer, Breast Cancer
Location: Charlotte NC, Norfolk VA, Winchester VA, Fairfax VA,
Sponsor: Jazz Pharmaceuticals
Sex: All
Age: 18+
Code: NCT07102381
Phase2, Recruiting
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
Location: Charlotte NC, Spartanburg SC, Winston-Salem NC,
Sponsor: Janssen Research & Development, LLC
Sex: Male
Age: 18+
Code: NCT07164443
Phase3, Recruiting
Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway
for
Cancer, Frail, Chemotherapy
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences
Sex: All
Age: 65+
Code: NCT07175376
Recruiting
LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients
for
Sarcoma
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences
Sex: All
Age: 0+
Code: NCT06958107
Recruiting
Pre-malignant States to Hematologic Malignancies in Firefighters
for
Clonal Hematopoiesis of Indeterminate Potential,
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences
Sex: All
Age: 40 - 49
Code: NCT06870760
Recruiting
Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma
for
Multiple Myeloma Refractory, Multiple Myeloma in Relapse
Location: Charlotte NC, Winston-Salem NC, Atlanta GA, Bethesda MD,
Sponsor: CellCentric Ltd.
Sex: All
Age: 18+
Code: NCT07096778
Phase2, Recruiting
E-Mindfulness Approaches for Living After Breast Cancer
for
Breast Cancer, Depression
Location: Charlotte NC, Matthews NC, Huntersville NC, Gastonia NC,
Sponsor: NRG Oncology
Sex: All
Age: 18 - 50
Code: NCT06748222
Phase3, Recruiting
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for
Prostate Cancer (Adenocarcinoma)
Location: Charlotte NC, Matthews NC, Gastonia NC, Concord NC,
Sponsor: Canadian Cancer Trials Group
Sex: Male
Age: 18+
Code: NCT06592924
Phase3, Recruiting
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
for
Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia
Location: Charlotte NC, Winston-Salem NC, Columbia SC,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 1 - 30
Code: NCT04546399
Phase2, Recruiting
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: BeOne Medicines
Sex: All
Age: 18+
Code: NCT06943872
Phase3, Recruiting
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Charlotte NC, Gastonia NC, Concord NC, Rock Hill SC,
Sponsor: NRG Oncology
Sex: All
Age: 18+
Code: NCT06532279
Phase2, Recruiting
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
for
B Acute Lymphoblastic Leukemia
Location: Charlotte NC, Winston-Salem NC, Columbia SC,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 1 - 46
Code: NCT06124157
Phase2, Recruiting
ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia
for
Acute Myeloid Leukemia
Location: Charlotte NC, Winston-Salem NC
Sponsor: Wake Forest University Health Sciences
Sex: All
Age: 18 - 64
Code: NCT06945042
Recruiting
Discharge Medication Use Post-Operatively in GU Cancer Patients
for
Genitourinary Cancer
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences
Sex: All
Age: 18+
Code: NCT06795087
Recruiting
A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)
for
Primary Myelofibrosis
Location: Charlotte NC, Cincinnati OH, Columbus OH, Tampa FL,
Sponsor: Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT06343805
Phase1, Recruiting
A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma
for
Advanced Hepatocellular Carcinoma
Location: Charlotte NC, Chicago IL, Toronto, Miami FL, Houston TX,