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Paid Clinical Trials Charlotte

Discover 644 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for
NASH - Nonalcoholic Steatohepatitis,
Location: Charlotte NC, Statesville NC, Columbia SC,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06528314

Phase3, Recruiting
Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for
NASH With Fibrosis, MASH With Fibrosis
Location: Charlotte NC, Statesville NC, Fayetteville NC,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06215716

Phase3, Recruiting
Active & Responsive

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for
Miscellaneous Neoplasm, Nos, Non-Neoplastic Condition, Nos
Location: Charlotte NC, Matthews NC, Huntersville NC,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07091617

Recruiting
Active & Responsive

Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

for
CLL/SLL
Location: Charlotte NC, Jacksonville FL, Canton OH, Cleveland OH,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18 - 70+

Code: NCT04215809

Phase1, Recruiting
Active & Responsive

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

for
Percutaneous Coronary Intervention,
Location: Charlotte NC, Winston-Salem NC, High Point NC,
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06909565

Recruiting

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Active & Responsive

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for
Atherosclerotic Cardiovascular Disease, Overweight, Obesity
Location: Charlotte NC, Monroe NC, Morganton NC, Winston-Salem NC,
Sponsor: Amgen

Sex: All

Age: 45 - 70+

Code: NCT07037433

Phase3, Recruiting
Active & Responsive

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for
Carcinoma, Non-Small-Cell Lung
Location: Charlotte NC, Winston-Salem NC, Knoxville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06623422

Phase3, Recruiting
Active & Responsive

Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections

for
Periprosthetic Joint Infection
Location: Charlotte NC, Durham NC, Lansing MI
Sponsor: OsteoRemedies, LLC

Sex: All

Age: 21+

Code: NCT06428448

Phase2, Recruiting
Active & Responsive

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for
Knee Cartilage Defects
Location: Charlotte NC, Morehead City NC, Lexington KY,
Sponsor: Medipost, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07339111

Phase3, Recruiting
Active & Responsive

A Study of RSLV-132 in Females With Sjögren's Disease

for
Primary Sjögren Syndrome
Location: Charlotte NC, Salisbury NC, Nashville TN,
Sponsor: Resolve Therapeutics

Sex: Female

Age: 18 - 70+

Code: NCT06440525

Phase2, Recruiting
Active & Responsive

Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease

for
Primary Sjogren's Disease
Location: Charlotte NC, Chesapeake VA, Rockville MD,
Sponsor: Vor Biopharma

Sex: All

Age: 18 - 70+

Code: NCT07404865

Phase3, Recruiting
Active & Responsive

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

for
End Stage Renal Disease (ESRD), Kidney Failure,
Location: Charlotte NC, Greenville SC, Orangeburg SC, Durham NC,
Sponsor: W.L.Gore & Associates

Sex: All

Age: 18 - 70+

Code: NCT04671771

Recruiting
Active & Responsive

A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows

for
Moderate to Severe Glabellar Lines
Location: Charlotte NC, Chapel Hill NC, Atlanta GA, Rockville MD,
Sponsor: Ipsen

Sex: All

Age: 18+

Code: NCT07435428

Phase3, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for
Crohn's Disease
Location: Charlotte NC, Chapel Hill NC, Atlanta GA, Macon GA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 16 - 70+

Code: NCT06430801

Phase3, Recruiting
Active & Responsive

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

for
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Location: Charlotte NC, Greensboro NC, Decatur GA, Macon GA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07266831

Phase2, Phase3, Recruiting
Active & Responsive

BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System

for
Leadless Pacemaker, Bradycardia, AV Block,
Location: Charlotte NC, Winston-Salem NC, Raleigh NC,
Sponsor: Biotronik, Inc.

Sex: All

Age: 18+

Code: NCT07118358

Recruiting
Active & Responsive

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for
Lower Extremity Acute Limb Ischemia, LE ALI
Location: Concord NC, West Columbia SC, Greenville SC,
Sponsor: Penumbra Inc.

Sex: All

Age: 18+

Code: NCT06747117

Recruiting
Active & Responsive

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

for
Relapsed/Refractory Multiple Myeloma
Location: Charlotte NC, Durham NC, Richmond VA, Lexington KY,
Sponsor: Caribou Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05722418

Phase1, Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for
Breast Neoplasms
Location: Charlotte NC, Roanoke VA, Midlothian VA, Richmond VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312176

Phase3, Recruiting
Active & Responsive

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for
Platinum-resistant Ovarian Cancer,
Location: Charlotte NC, Winston-Salem NC, Charleston SC,
Sponsor: Genelux Corporation

Sex: Female

Age: 18+

Code: NCT05281471

Phase3, Recruiting