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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

CARE Study: Cancer, Asian Americans, and Relationship Enrichment

for
Neoplasm
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 21 - 70+

Code: NCT06782581

Recruiting
Active & Responsive

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for
NSCLC Adenocarcinoma, Gastroesophageal Cancer (GC),
Location: New York NY, East Brunswick NJ, Philadelphia PA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18+

Code: NCT07277413

Phase1, Recruiting
Active & Responsive

Susan G. Komen's ShareForCures

for
Breast Cancer
Location: Dallas TX
Sponsor: Susan G. Komen Breast Cancer Foundation

Sex: All

Age: 18+

Code: NCT05654246

Recruiting
Active & Responsive

NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors

for
Solid Tumor, KRAS Mutation-Related Tumors
Location: Washington D.C. DC
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT05661201

Phase1, Recruiting
Active & Responsive

Lopinavir/Ritonavir in PLWH With High-Grade AIN

for
High-Grade Anal Intraepithelial Neoplasia
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT05334004

Phase1, Recruiting

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Active & Responsive

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

for
Metastatic Non-small Cell Lung Cancer
Location: Shirley NY, New Hyde Park NY, The Bronx NY, New York NY,
Sponsor: NovoCure GmbH

Sex: All

Age: 18+

Code: NCT06216301

Phase3, Recruiting
Active & Responsive

TCF-001 TRACK (Target Rare Cancer Knowledge) Study

for
Rare Cancers, Cholangiocarcinoma,
Location: Cambridge MA
Sponsor: TargetCancer Foundation

Sex: All

Age: 18+

Code: NCT04504604

Recruiting
Active & Responsive

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

for
Localized Renal Pelvis and Ureter Urothelial Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: Male

Age: 18+

Code: NCT01050504

Recruiting
Active & Responsive

A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer

for
Breast Cancer, Breast Neoplasm, Breast Cancer Stage IV
Location: Sarasota FL, Nashville TN, Beverly Hills CA
Sponsor: MBQ Pharma

Sex: All

Age: 21+

Code: NCT06075810

Phase1, Recruiting
Active & Responsive

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

for
Non-small Cell Lung Cancer
Location: New York NY, Tampa FL, Elizabethtown KY, Birmingham AL
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06841055

Phase2, Recruiting
Active & Responsive

Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female

Age: 18+

Code: NCT05417308

Early_phase1, Recruiting
Active & Responsive

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors, Genital Neoplasm, Female,
Location: Boston MA, Bethesda MD, Toronto, Celebration FL,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05592626

Phase1, Phase2, Recruiting
Active & Responsive

MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other

for
Cancer, Adjustment Disorders
Location: Rockville MD
Sponsor: Sunstone Medical

Sex: All

Age: 18+

Code: NCT05584826

Phase2, Recruiting
Active & Responsive

PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery.

for
Frailty, Oncology Problem, Cognitive Impairment
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 70+

Code: NCT06022666

Recruiting
Active & Responsive

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

for
Advanced Non-squamous Non-small-cell Lung Cancer,
Location: Mullica Hill NJ, Miami FL, Plantation FL,
Sponsor: Genelux Corporation

Sex: All

Age: 18+

Code: NCT06463665

Phase2, Recruiting
Active & Responsive

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for
Diffuse Midline Glioma (DMG), Glioblastoma,
Location: Philadelphia PA, Washington D.C. DC, Atlanta GA,
Sponsor: Sabine Mueller, MD, PhD

Sex: All

Age: 2 - 21

Code: NCT04732065

Phase1, Recruiting
Active & Responsive

Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

for
Advanced Solid Tumor
Location: Pittsburgh PA, Houston TX, Beverly Hills CA
Sponsor: Strand Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06249048

Phase1, Phase2, Recruiting
Active & Responsive

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for
Hematologic Malignancy, GvHD, GVHD,Acute, GVHD, Chronic,
Location: Boston MA, New York NY, Minneapolis MN, Seattle WA,
Sponsor: Tr1X, Inc.

Sex: All

Age: 18+

Code: NCT06462365

Phase1, Recruiting
Active & Responsive

A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation

for
Colorectal Cancer, Advanced Adenocarcinoma
Location: Raonoke VA
Sponsor: Universal Diagnostics

Sex: All

Age: 45 - 70+

Code: NCT06059963

Recruiting
Active & Responsive

A Study of PHST001 in Advanced Solid Tumors

for
Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Pheast Therapeutics

Sex: All

Age: 18+

Code: NCT06840886

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer