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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

TCR1188-ABC Cells in KRAS-mutated Cancers

for
Cholangiocarcinoma, Colorectal Cancer,
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07594067

Phase1, Recruiting
Active & Responsive

Sun Safe Together: A Digital Skin Cancer Prevention Intervention for Adolescents and Their Parents

for
Skin Cancer Prevention
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 13+

Code: NCT07681791

Recruiting
Active & Responsive

Burn Pit Exposure in Veterans: A Cancer Screening Pilot Study at the Inova Saville Cancer Screening & Prevention Center

for
Cancer
Location: Fairfax VA
Sponsor: Inova Health Care Services

Sex: All

Age: 35 - 70+

Code: NCT07485322

Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

for
Advanced Solid Tumor Cancer,
Location: Aurora CO, Boulder CO
Sponsor: University of Colorado, Boulder

Sex: All

Age: 18+

Code: NCT07636200

Recruiting

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Active & Responsive

Home-based Vision Rehabilitation Guided by Brain Imaging

for
Visual Field Defect, Stroke, Hemianopia Homonymous,
Location: Washington D.C. DC
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT07635329

Recruiting
Active & Responsive

A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)

for
Non-small Cell Lung Cancer
Location: Albany NY, Lincoln NE
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07554339

Phase3, Recruiting
Active & Responsive

A Tailored, Web-based Program (COMPASS) to Improve Exercise and Dietary Changes in Stage I-III Pancreatic Cancer Patients Receiving Neoadjuvant Chemotherapy

for
Stage I Pancreatic Cancer AJCC v8,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07651358

Recruiting
Active & Responsive

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

for
Sub-study 1 Cervical Cancer (Volrustomig Monotherapy),
Location: Stony Brook NY, New York NY, Montreal, Baltimore MD,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06535607

Phase2, Recruiting
Active & Responsive

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer

for
Advanced Breast Cancer, Early Breast Cancer
Location: Westbury NY, The Bronx NY, New York NY, Amsterdam NY,
Sponsor: TerSera Therapeutics LLC

Sex: Female

Age: 18 - 55

Code: NCT07310420

Phase1, Recruiting
Active & Responsive

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

for
Solid Tumors
Location: St. Petersburg FL, Germantown TN, Rochester MN,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07415031

Phase2, Recruiting
Active & Responsive

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

for
Non-small Cell Lung Cancer
Location: New Haven CT, White Plains NY, Montreal, Kingston,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07513376

Phase3, Recruiting
Active & Responsive

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Castration Resistant Metastatic Prostate Cancer,
Location: Miami FL, Grand Rapids MI, Omaha NE, Irvine CA
Sponsor: Aktis Oncology, Inc.

Sex: Male

Age: 18+

Code: NCT07581184

Phase1, Recruiting
Active & Responsive

Bundled Cancer Screening and Genetic Services Navigation

for
Breast Cancer Screening, Colon Cancer Screening,
Location: Newark DE, Washington D.C. DC
Sponsor: Georgetown University

Sex: Female

Age: 45 - 70+

Code: NCT07228000

Recruiting
Active & Responsive

Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab

for
Breast Cancer Triple Negative, Breast Cancer Stage II,
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT05877859

Recruiting
Active & Responsive

Short Course Radiotherapy

for
Central Nervous System Cancer
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 0 - 21

Code: NCT07147179

Recruiting
Active & Responsive

High Dose Radiation Therapy With Pembrolizumab and Chemotherapy for the Treatment of Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06492759

Phase2, Recruiting
Active & Responsive

Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer

for
HR+ HER2- Breast Cancer
Location: Nashville TN, Austin TX, San Antonio TX, Lone Tree CO,
Sponsor: Faeth Therapeutics

Sex: All

Age: 18+

Code: NCT07558733

Phase1, Phase2, Recruiting
Active & Responsive

Eatwell Clinical Trial (R01)

for
Cancer Prevention, Dietary Guidelines
Location: Philadelphia PA
Sponsor: Drexel University

Sex: All

Age: 18+

Code: NCT07225881

Recruiting
Active & Responsive

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for
FGFR2 Gene Fusion/Rearrangement, Other Solid Tumors, Adult
Location: Boston MA, New York NY, Tampa FL, Chicago IL,
Sponsor: Elevar Therapeutics

Sex: All

Age: 18+

Code: NCT07359820

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer