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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Phase 1 Study Of Izalontamab Brengitecan + Adagrasib In NSCLC - The IZA-A Trial

for
Non-small Cell Lung Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07382726

Phase1, Recruiting
Active & Responsive

Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor

for
Malignant Peripheral Nerve Sheath Tumors, MPNST
Location: Cleveland OH
Sponsor: Ankit Mangla, MD

Sex: All

Age: 12+

Code: NCT07549022

Phase1, Phase2, Recruiting
Active & Responsive

Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST

for
Malignant Peripheral Nerve Sheath Tumor (MPNST),
Location: Washington D.C. DC, Dallas TX
Sponsor: AeRang Kim

Sex: All

Age: 18+

Code: NCT06735820

Phase1, Phase2, Recruiting
Active & Responsive

A Study in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration Resistant Prostate Cancer, mCRPC,
Location: East Brunswick NJ, Fairfax VA, Myrtle Beach SC,
Sponsor: Flare Therapeutics Inc.

Sex: Male

Age: 18+

Code: NCT07719361

Phase1, Recruiting
Active & Responsive

Asciminib in HER2+ Breast Cancer Brain Metastases

for
HER2+ Metastatic Breast Cancer
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 18+

Code: NCT07136428

Phase1, Phase2, Recruiting

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Active & Responsive

Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

for
Cascade Testing, Lynch Syndrome, Decision Making,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18+

Code: NCT07106359

Recruiting
Active & Responsive

First-Line Ipilimumab Plus Nivolumab and Nogapendekin Alfa Inbakicept (N-803) in Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer

for
Non-small Cell Lung Cancer Stage IV,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07355205

Phase1, Phase2, Recruiting
Active & Responsive

Feasibility of a Habit-Based Intervention to Reduce Sedentary Behaviour in Cancer Survivors

for
Cancer, Sedentary Behaviour
Location: Toronto
Sponsor: University of Toronto

Sex: All

Age: 18+

Code: NCT07694479

Recruiting
Active & Responsive

Cs-131LDR Brachytherapy for Organ-Preserving Irradiation for Recurrent Cervical and Endometrial Cancer

for
Gynecologic Cancer
Location: Lexington KY
Sponsor: Denise Fabian

Sex: Female

Age: 18+

Code: NCT07631572

Recruiting
Active & Responsive

Remotely-Delivered Cognitive Behavioral Stress Management for Breast Cancer (R-CBSM)

for
Breast Cancer
Location: Coral Gables FL
Sponsor: University of Miami

Sex: Female

Age: 50+

Code: NCT07502352

Recruiting
Active & Responsive

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

for
Clear Cell Renal Cell Cancer (ccRCC),
Location: San Francisco CA
Sponsor: Kelly Fitzgerald, MD

Sex: All

Age: 18+

Code: NCT07043608

Phase2, Recruiting
Active & Responsive

A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Locally Advanced Non-Small Cell Lung Cancer (NSCLC),
Location: Omaha NE, Grand Island NE
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07680764

Phase2, Recruiting
Active & Responsive

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

for
Colorectal Cancer
Location: East Brunswick NJ, Charlottesville VA, Tampa FL,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07659795

Phase2, Recruiting
Active & Responsive

Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.

for
Reccurent/Metastatic Solid Tumor Disease,
Location: Quebec
Sponsor: CHU de Quebec-Universite Laval

Sex: Male

Age: 18+

Code: NCT07483658

Recruiting
Active & Responsive

An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial

for
Primary Brain Neoplasm
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT07278440

Recruiting
Active & Responsive

TCR1188-ABC Cells in KRAS-mutated Cancers

for
Cholangiocarcinoma, Colorectal Cancer,
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07594067

Phase1, Recruiting
Active & Responsive

Sun Safe Together: A Digital Skin Cancer Prevention Intervention for Adolescents and Their Parents

for
Skin Cancer Prevention
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 13+

Code: NCT07681791

Recruiting
Active & Responsive

Burn Pit Exposure in Veterans: A Cancer Screening Pilot Study at the Inova Saville Cancer Screening & Prevention Center

for
Cancer
Location: Fairfax VA
Sponsor: Inova Health Care Services

Sex: All

Age: 35 - 70+

Code: NCT07485322

Recruiting
Active & Responsive

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

for
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07675967

Recruiting
Active & Responsive

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

for
Advanced Solid Tumor Cancer,
Location: Aurora CO, Boulder CO
Sponsor: University of Colorado, Boulder

Sex: All

Age: 18+

Code: NCT07636200

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer