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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1

Evaluating Tolerability of ePUHRT With Brachytherapy Boost

for
Prostate Cancer
Location: Indianapolis IN
Sponsor: Indiana University

Sex: Male

Age: 18+

Code: NCT06817668

Recruiting

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics

for
Hematologic Malignancies, Lymphoma, Multiple Myeloma, Leukemia,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 60+

Code: NCT06296368

Recruiting

Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome

for
Neuroblastoma
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 0+

Code: NCT00588068

Recruiting

Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer

for
Biliary Tract Cancer, Cholangiocarcinoma
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 21+

Code: NCT06546969

Phase1, Recruiting

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

for
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype,
Location: New York NY, Chicago IL, Houston TX, Dallas TX,
Sponsor: Debiopharm International SA

Sex: All

Age: 18+

Code: NCT05765812

Phase1, Phase2, Recruiting

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Remote Temperature Monitoring of Patients At Risk for Developing Fever

for
Fever, Cancer, Remote Patient Monitoring
Location: Schenectady NY
Sponsor: AION Biosystems

Sex: All

Age: 18+

Code: NCT06752512

Recruiting

Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC

for
Advanced Cancer, Clear Cell Renal Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05663710

Phase1, Phase2, Recruiting

Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06640010

Recruiting

Nerve Grafting Technique to Preserve Erectile Function in Patients Undergoing Robotic Assisted Radical Prostatectomy

for
Prostate Cancer, Erectile Dysfunction
Location: Montreal
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital

Sex: Male

Age: 18+

Code: NCT06521710

Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 39

Code: NCT05800210

Phase2, Recruiting

Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning

for
Locally Advanced Malignant Solid Neoplasm,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT04515810

Recruiting

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for
Advanced Malignant Solid Neoplasm,
Location: Bethesda MD, Richmond VA, Charlottesville VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05327010

Phase2, Recruiting

Regorafenib Combined With Fulvestrant in Recurrent Low-Grade Serous Ovarian Cancer

for
Ovarian Cancer, Serous Ovarian Cancer
Location: Cleveland OH
Sponsor: Sarah K. Lynam MD

Sex: Female

Age: 18+

Code: NCT05113368

Phase2, Recruiting

Pancreatic Cancer Genetics

for
Pancreatic Cancer
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18 - 70+

Code: NCT01102569

Recruiting

Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

for
Cholangiocarcinoma, Multiple Myeloma, Colon Cancer,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06340646

Recruiting

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

for
Gestational Diabetes Mellitus, Pregnancy, High Risk
Location: Boston MA, Providence RI, New York NY, Philadelphia PA,
Sponsor: Ohio State University

Sex: Female

Age: 18+

Code: NCT06445946

Recruiting

Rural Adult and Youth Sun Protection Study

for
Melanoma (Skin), Skin Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 3 - 7

Code: NCT06439979

Recruiting

Assessment of Neural Signals for the Control of Assistive Devices

for
Spinal Cord Injury (SCI), Initial Encounter
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT06533969

Recruiting

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

for
Mantle Cell Lymphoma, Non Hodgkin Lymphoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05529069

Phase2, Recruiting

MCW Master Predict (Profile Related Evidence Determining Individualized Cancer Therapy)

for
Cancer
Location: Milwaukee WI
Sponsor: Sameem M. Abedin, MD

Sex: All

Age: 18+

Code: NCT05802069

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer