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Oncology Clinical Trials

Browse 9,276 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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1

Early Onset Colorectal Cancer Detection

for
Colorectal Cancer, Colorectal Neoplasms,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 50

Code: NCT06342401

Recruiting

Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 2+

Code: NCT05580601

Phase 1, Phase 2, Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

for
Advanced Endometrial Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05039801

Phase 1, Recruiting

Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell Malignancies

for
B-Cell Malignancies
Location: Canton OH
Sponsor: TransThera Sciences (Nanjing), Inc.

Sex: All

Age: 18+

Code: NCT05275504

Phase 1, Recruiting

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for
Metastatic Melanoma, Unresectable Melanoma, Melanoma
Location: Lebanon NH, Montreal, Camden NJ, Bethesda MD, Toronto,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT05727904

Phase 3, Recruiting

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Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis

for
Hepatocellular Carcinoma, Cirrhosis, Liver
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 18+

Code: NCT06526104

Phase 2, Recruiting

Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction

for
Mandible Tumor, Mandibular Injuries, Mandible; Deformity
Location: Cleveland OH, San Antonio TX, San Francisco CA
Sponsor: Epibone, Inc.

Sex: All

Age: 18 - 65

Code: NCT03678467

Phase 1, Phase 2, Recruiting

Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors

for
Breast Cancer
Location: Montreal, Oklahoma City OK
Sponsor: Medifocus, Inc.

Sex: Female

Age: 18+

Code: NCT01204801

Phase 3, Recruiting

Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

for
Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell Lymphoma
Location: Rochester MN
Sponsor: Academic and Community Cancer Research United

Sex: All

Age: 18+

Code: NCT05910801

Phase 2, Recruiting

MRI-Guided Ultrasound Stimulated Microbubbles Radiation Treatment for Patients with Chest-Wall and Locally Advanced Breast Cancer

for
Breast Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06633601

Phase 1, Recruiting

Developing a Functional Cure for HIV Disease: Clinical Specimen Collection From HIV Positive Individuals

for
HIV Infections
Location: Baltimore MD
Sponsor: American Gene Technologies International Inc.

Sex: All

Age: 18 - 60

Code: NCT03215004

Recruiting

IDENTIFY Study: Natural History of Maternal Neoplasia

for
Maternal Neoplasia
Location: Bethesda MD
Sponsor: National Human Genome Research Institute (NHGRI)

Sex: Female

Age: 18 - 70+

Code: NCT04049604

Recruiting

Combination of TATE and PD-1 Inhibitor in Liver Cancer

for
Hepatocellular Carcinoma, Gastric Cancer
Location: Milwaukee WI, Oklahoma City OK, Orange CA
Sponsor: Teclison Ltd.

Sex: All

Age: 18 - 70+

Code: NCT03259867

Phase 2, Recruiting

Pre-operative Hypofractionated Proton Therapy

for
Soft Tissue Sarcoma
Location: Washington D.C. DC
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT05917301

Recruiting

Accelerated Pulmonary Rehabilitation in the Preoperative Period

for
Chronic Obstructive Pulmonary Disease, Lung Cancer
Location: Burlington VT
Sponsor: University of Vermont

Sex: All

Age: 18+

Code: NCT06432972

Recruiting

Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

for
Recurrent or Refractory Solid Tumors, Ewing Sarcoma,
Location: Cincinnati OH, Milwaukee WI, Dallas TX,
Sponsor: South Plains Oncology Consortium

Sex: All

Age: 1 - 20

Code: NCT02013336

Phase 1, Recruiting

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency

for
Inherited Bone Marrow Failure Syndrome,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06090669

Phase 1, Recruiting

Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

for
Gastric Cancer, Gastric Neoplasm,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 6+

Code: NCT04557969

Recruiting

Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)

for
Pediatric Cancer
Location: Chicago IL
Sponsor: Erin Rowell

Sex: Female

Age: 0 - 30

Code: NCT05309746

Recruiting

Exercise to ReGain Stamina and Energy (The EXERGISE Study)

for
Fatigue, Breast Cancer, Cancer, Therapy-Related
Location: Gainesville FL
Sponsor: University of Florida

Sex: Female

Age: 60 - 70+

Code: NCT05684367

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer