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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas

for
Follicular Lymphoma, Marginal Zone Lymphoma, B-Cell Lymphoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06350318

Phase 2, Recruiting

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

for
Glioma, Malignant Brain Neoplasm, Meningioma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06650163

Phase 1, Recruiting

Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy

for
Brain Tumor
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT03286335

Recruiting

Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

for
Breast Neoplasm Female
Location: Madison WI, Iowa City IA
Sponsor: University of Wisconsin, Madison

Sex: Female

Age: 18+

Code: NCT03096418

Recruiting

Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence

for
Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia,
Location: Nashville TN
Sponsor: University of Tennessee

Sex: All

Age: 18+

Code: NCT04663100

Recruiting

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Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer

for
Inflammatory Breast Carcinoma, Invasive Breast Carcinoma,
Location: Jacksonville FL, Nassau Bay TX, Houston TX,
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT00477100

Recruiting

MRg-NIRS Imaging System Breast Cancer Trial

for
Breast Cancer
Location: Lebanon NH
Sponsor: Keith D. Paulsen

Sex: Female

Age: 18 - 70+

Code: NCT06400563

Recruiting

Hydrogen Peroxide Trial to Investigate the Efficacy of 30%H2O2 as a Topical Application Before Definitive Treatment

for
Basal Cell Carcinoma,
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT04929535

Phase 2, Recruiting

Artificial Intelligence (AI) Cytopathology Trial

for
Pancreatic Solid Lesions
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18 - 70+

Code: NCT05018663

Recruiting

Quality of Life Assessment of Cryotherapy in Esophageal or Gastroesophageal Cancer

for
Esophageal Cancer
Location: Goodyear AZ
Sponsor: Western Regional Medical Center

Sex: All

Age: 18 - 70+

Code: NCT03285035

Recruiting

Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer

for
Pancreatic Adenocarcinoma
Location: Seattle WA
Sponsor: Benaroya Research Institute

Sex: All

Age: 18+

Code: NCT03703063

Phase 1, Recruiting

5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC

for
Squamous Cell Carcinoma of Head and Neck
Location: New Haven CT
Sponsor: Barbara Burtness

Sex: All

Age: 18+

Code: NCT05317000

Phase 2, Recruiting

The ONE-MIND Study: Evaluating the Efficacy of Online Mindfulness-Based Cancer Recovery During Chemotherapy Treatment

for
Breast Cancer, Colorectal Cancer, Chemotherapy Effect
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT03484000

Recruiting

OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases

for
Liver Metastases, Stereotactic Body Radiation Therapy,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT04020276

Recruiting

Hyperthermia With Chemotherapy for Locally Advanced or Metastatic Pancreas Cancer

for
Pancreatic Neoplasms
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT00178763

Phase 2, Recruiting

Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer

for
Localized Prostate Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: Male

Age: 30 - 70+

Code: NCT06389786

Recruiting

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

for
Renal Tumor Histology, Cutaneous Leiomyoma, Kidney Cancer
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2+

Code: NCT00050752

Recruiting

Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring

for
Breast Carcinoma, Breast Neoplasm
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04799535

Recruiting

Arizona Cancer Center Biospecimen Repository

for
Cancer
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 18+

Code: NCT00896935

Recruiting

Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

for
Advanced Ovarian Carcinoma,
Location: Boston MA, Mineola NY, New York NY, Bethlehem PA,
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT04575935

Phase 3, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer