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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Non-Hodgkin Lymphoma

for
Lymphoma, Non-Hodgkin Lymphoma, B-Cell
Location: Cleveland OH
Sponsor: Luminary Therapeutics

Sex: All

Age: 18+

Code: NCT05312801

Phase1, Recruiting

DART: Diagnostic-CT-Enabled Planning: A Randomized Trial in Palliative Radiation Therapy

for
Advanced Cancer Requiring Palliative Radiation
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT05233904

Recruiting

Cabozantinib to Treat Recurrent Liver Cancer Post Transplant

for
Hepatocellular Carcinoma, Recurrent Cancer, Liver Transplant
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04204850

Phase2, Recruiting

A Dose Escalation and Expansion Study of GIGA-564 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

for
Advanced or Metastatic Solid Tumor Malignancies
Location: Bethesda MD
Sponsor: GigaGen, Inc.

Sex: All

Age: 18+

Code: NCT06258304

Phase1, Recruiting

ETHAN - ET for Male BC

for
Male Breast Cancer, Hormone Receptor-positive Breast Cancer,
Location: Boston MA, Philadelphia PA, Washington D.C. DC,
Sponsor: Jose Pablo Leone

Sex: Male

Age: 18+

Code: NCT05501704

Phase2, Recruiting

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A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

for
Head and Neck Cancer, Head Cancer, Head Cancer Neck,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04722523

Phase1, Recruiting

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

for
Muscle-Invasive Bladder Carcinoma, Tumor
Location: Los Angeles CA
Sponsor: Leslie Ballas

Sex: All

Age: 18+

Code: NCT06417190

Phase2, Recruiting

Telehealth Intervention for Improving Distress and Financial Toxicity in the Caregivers

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Winston-Salem NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06709404

Recruiting

Perceptions of Hospital Care at Home for Patients With Cancer: A Qualitative Study of Cancer Providers, Patients and Caregivers.

for
Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05694650

Recruiting

Multi-Institutional Registry for Prostate Cancer Radiosurgery

for
Prostate Cancer Early Risk Treated by Radiosurgery,
Location: Red Bank NJ, Havertown PA, Johnson City NY,
Sponsor: RPCR, Inc.

Sex: Male

Age: 18 - 70+

Code: NCT01226004

Recruiting

Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment

for
Lung Cancer
Location: Lexington KY
Sponsor: Laurie McLouth

Sex: All

Age: 18+

Code: NCT06047301

Recruiting

Ipatasertib and Docetaxel in Metastatic NSCLC Patients Who Have Failed 1st Line Immunotherapy

for
NSCLC Stage IV, NSCLC Stage IIIB
Location: Kansas City KS, Fairway KS
Sponsor: Jun Zhang, MD, PhD

Sex: All

Age: 18+

Code: NCT04467801

Phase2, Recruiting

Using Biomarkers for Diagnosis, Risk Stratification of Post -Treatment Recurrence and Long-Term Surveillance of Lung Cancer

for
Lung; Node, Adenocarcinoma of Lung
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05665504

Recruiting

Characterization of Receptors in Non-functioning Pituitary Macroadenomas

for
Pituitary Tumor
Location: Chicago IL
Sponsor: Cook County Health

Sex: All

Age: 18+

Code: NCT00852501

Recruiting

Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma

for
Glioma
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT04543201

Recruiting

A Randomized Controlled Trial to Assess the Impact of Live and Recorded Music-Based Interventions on Pre-operative Stress, Mood, Pain and Biomarkers, in Neurosurgical Patients (Music-STAR Trial)

for
Stress, Pain
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06536504

Recruiting

Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma

for
Myeloma Multiple
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05091372

Phase2, Recruiting

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

for
OligoProgressive Metastatic Disease
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06367972

Phase2, Phase3, Recruiting

Connect for Cancer Prevention Study (Connect)

for
Cancer, General Research Use
Location: Detroit MI, Atlanta GA, Marshfield WI, Minneapolis MN,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 30 - 70

Code: NCT04609072

Recruiting

TRUDI: TDXD+Durva in HER2+/Low IBC

for
Invasive Breast Cancer, Inflammatory Breast Cancer Stage III,
Location: Boston MA, Houston TX
Sponsor: Filipa Lynce, MD

Sex: Female

Age: 18+

Code: NCT05795101

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer