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Oncology Clinical Trials

Browse 9,263 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Phase II Study of RP2 as Immunoprevention in High-Risk Oral Precancerous Disease

for
High-Risk Oral Precancerous Disease
Location: Boston MA
Sponsor: Glenn J. Hanna

Sex: All

Age: 18+

Code: NCT06623110

Phase 2, Recruiting

Role of the Immune Environment in Response to Therapy in Breast Cancer

for
Breast Cancer, ER Positive Breast Cancer,
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female

Age: 18+

Code: NCT05396612

Recruiting

Time Restricted Eating During Chemotherapy for Breast Cancer

for
Breast Cancer Female
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: Female

Age: 25 - 70+

Code: NCT05259410

Recruiting

Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis

for
Leptomeningeal Metastasis, Leptomeningeal Disease,
Location: Houston TX
Sponsor: University of Zurich

Sex: All

Age: 18+

Code: NCT06417710

Recruiting

Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men

for
Prostate Carcinoma
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 21 - 70+

Code: NCT06541210

Recruiting

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Comparing Moderately and Ultra Hypofractionated Radiation Treatments for Post-operative Prostate Cancer

for
Post-Operative Prostate Cancer
Location: Toronto, London
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18+

Code: NCT06409910

Phase 2, Recruiting

DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY

for
Cancer of the Breast, Chemotherapy-induced Neuropathy
Location: New Haven CT, Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 40+

Code: NCT06749210

Phase 2, Recruiting

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Commack NY, Uniondale NY, Mineola NY, Harrison NY,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06500481

Phase 3, Recruiting

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

for
Metastatic Malignant Solid Neoplasm,
Location: Boston MA, Mineola NY, New York NY, Bethesda MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05687110

Phase 1, Recruiting

Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology

for
Hip Dysplasia
Location: Quebec, New York NY, Ottawa, Royal Oak MI, Chicago IL,
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 16 - 50

Code: NCT03481010

Recruiting

Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence

for
ENSAT Stage I Adrenal Cortex Carcinoma,
Location: Ann Arbor MI, Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03583710

Phase 3, Recruiting

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for
Cutaneous Squamous Cell Carcinoma (CSCC)
Location: Beverly MA, Portsmouth NH, Boston MA, New York NY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06585410

Phase 3, Recruiting

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT05464810

Early Phase 1, Recruiting

Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS)

for
Clonal Cytopenia of Undetermined Significance,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05483010

Phase 2, Recruiting

A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

for
Recurrent Head and Neck Squamous Cell Carcinoma
Location: Providence RI, Philadelphia PA, Miami FL, Tampa FL,
Sponsor: Rakuten Medical, Inc.

Sex: All

Age: 18+

Code: NCT06699212

Phase 3, Recruiting

Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy

for
Prostate Cancer
Location: Halifax, Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: Male

Age: 18+

Code: NCT05169112

Phase 3, Recruiting

Universal Germline Testing in the Community

for
Cancer, Solid Tumor, Solid Tumor, Adult
Location: Rock Hill SC
Sponsor: Invitae Corporation

Sex: All

Age: 18+

Code: NCT05416710

Recruiting

First in Human Study of UCT-03-008 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Dallas TX, Los Angeles CA
Sponsor: 1200 Pharma, LLC

Sex: All

Age: 18+

Code: NCT05103046

Phase 1, Recruiting

Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical Study

for
Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05879146

Phase 2, Recruiting

An Evaluation of Polymer Based Fiducials for Use in Imaging Patients Receiving Treatment for Prostate Cancer

for
Prostate Adenocarcinoma
Location: Warrenville IL
Sponsor: John Chang, MD

Sex: Male

Age: 0+

Code: NCT01478412

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer