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Oncology Clinical Trials

Browse 9,028 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

for
Lymphoma, Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03223610

Phase1, Phase2, Recruiting

Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme

for
Glioblastoma Multiforme
Location: Stony Brook NY
Sponsor: Stony Brook University

Sex: All

Age: 18+

Code: NCT05423210

Early_phase1, Recruiting

Cannabis Use and Outcomes in Black and White Patients With Cancer

for
Cancer
Location: Philadelphia PA, Buffalo NY
Sponsor: State University of New York at Buffalo

Sex: All

Age: 21 - 70+

Code: NCT06037681

Recruiting

Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma

for
Recurrent Endometrial Carcinoma,
Location: Miami FL
Sponsor: Aaron Wolfson

Sex: Female

Age: 18+

Code: NCT05603910

Phase1, Recruiting

18F-DOPA II - PET Imaging Optimization

for
Congenital Hyperinsulinism, Neuroblastoma, Parkinson Disease,
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 0+

Code: NCT04706910

Phase3, Recruiting

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BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

for
Limited Stage Small Cell Lung Cancer
Location: White Plains NY, Norfolk VA, Fairfax VA, Wilson NC,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 18+

Code: NCT06773910

Phase2, Recruiting

The SUGAR Study; SBRT and Relugolix) for Prostate Cancer

for
Prostate Cancer
Location: New Haven CT, New York NY, Seattle WA
Sponsor: Yale University

Sex: Male

Age: 18+

Code: NCT06111781

Phase2, Recruiting

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

for
Giant Cell Tumor of Bone
Location: Boston MA, Baltimore MD, Pittsburgh PA, Cleveland OH,
Sponsor: St. Louis University

Sex: All

Age: 18+

Code: NCT03295981

Phase3, Recruiting

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT06088381

Phase2, Recruiting

Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

for
Cancer, Fatigue
Location: Winston-Salem NC, Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06634381

Recruiting

Testing Two Interventions to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV

for
HIV
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 50+

Code: NCT06269081

Recruiting

Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

for
Ewing Sarcoma, Osteosarcoma, Sarcomas
Location: Philadelphia PA, Aurora CO, San Francisco CA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 5 - 40

Code: NCT06156410

Phase1, Recruiting

Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

for
Stomach Cancer, Gastro-Esophageal(GE) Junction Cancer,
Location: Stanford CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT01048281

Recruiting

TumorGlow Intraoperative Molecular Imaging (IMI)

for
Tumor, Solid
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT04723810

Phase1, Phase2, Recruiting

Refining Local-Regional Therapy for IBC

for
Breast Cancer, Inflammatory Breast Cancer, Sentinel Lymph Node
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: Female

Age: 18+

Code: NCT04636710

Recruiting

Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling

for
Li-Fraumeni Syndrome
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT05126810

Recruiting

Development and Evaluation of a Screening Approach for Sexual Dysfunction in AYA Patients With and Surviving Childhood Cancer

for
Pediatric Cancer, Survivorship
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 15 - 24

Code: NCT05524610

Recruiting

Digital Sizing for Orthopaedic Hip Implants

for
Hip Arthritis
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 0+

Code: NCT00665210

Recruiting

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT05098210

Phase1, Recruiting

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for
Stage III Ovarian Cancer, Stage IV Ovarian Cancer,
Location: Hartford CT, New Haven CT, New York NY, Teaneck NJ,
Sponsor: GOG Foundation

Sex: Female

Age: 18+

Code: NCT05659381

Phase3, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer