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Oncology Clinical Trials

Browse 9,272 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

for
Anatomic Stage I Breast Cancer, Anatomic Stage II Breast Cancer,
Location: Nashville TN, Dallas TX
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05919108

Phase 2, Recruiting

A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer

for
Non-muscle Invasive Bladder Cancer,
Location: New York NY, New Brunswick NJ, Tampa FL,
Sponsor: John Sfakianos

Sex: All

Age: 18+

Code: NCT06503614

Phase 2, Recruiting

Comparison of Direct Anterior Approach vs. Lateral Hemiarthroplasty for Femoral Neck Fracture Repair

for
Hip Fractures
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT05173155

Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for
Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer,
Location: Boston MA, Providence RI, Montreal, Fairfax VA, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05797168

Phase 1, Phase 2, Recruiting

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

for
SCLC
Location: New Haven CT, Hackensack NJ, Fairfax VA, Durham NC,
Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All

Age: 18+

Code: NCT06179069

Phase 1, Recruiting

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A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer

for
Hepatocellular Carcinoma, Cirrhosis
Location: Fairfax VA
Sponsor: Inova Health Care Services

Sex: All

Age: 18+

Code: NCT06007846

Phase 2, Phase 3, Recruiting

A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS

for
Advanced Solid Tumors
Location: Miami Beach FL, St. Petersburg FL, New Orleans LA
Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Sex: All

Age: 18+

Code: NCT05277168

Phase 1, Phase 2, Recruiting

A Study of BI-1206 in Combination With Rituximab With or Without Acalabrutinib in Subjects With Indolent B-Cell NHL

for
Indolent B-Cell Non-Hodgkin Lymphoma
Location: Louisville KY
Sponsor: BioInvent International AB

Sex: All

Age: 18+

Code: NCT03571568

Phase 1, Phase 2, Recruiting

Ending the HIV Epidemic: An All-facility Intervention for Patient and Healthcare Staff Well-being

for
Stigma, HIV, Well-Being, Psychological
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT05785169

Recruiting

Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

for
Breast Cancer, Oligoprogressive, Head and Neck Cancer, Sarcoma,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06103669

Recruiting

Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

for
Lung Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT00898313

Recruiting

Study of TBX-3400 in Subjects With Solid Malignant Tumors Resistant or Refractory to Standard Therapies

for
Cancer, Tumor, Solid, Refractory Cancer
Location: Los Angeles CA
Sponsor: Taiga Biotechnologies, Inc.

Sex: All

Age: 18+

Code: NCT04640246

Phase 1, Phase 2, Recruiting

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue

for
Pediatric Sarcoma, Refractory, Pediatric Sarcoma, Relapsed
Location: The Bronx NY, Philadelphia PA, Durham NC,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 2 - 40

Code: NCT05634369

Phase 1, Phase 2, Recruiting

Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life

for
Prostate Cancer
Location: Chicago IL
Sponsor: University of Chicago

Sex: Male

Age: 18+

Code: NCT06171269

Recruiting

Quality of Life for Subjects Receiving Androgen Deprivation Therapy and Have a Doubling in PSA of Either Less Than or Greater Than 1 Year

for
Prostate Cancer
Location: Greenfield Park
Sponsor: Urology South Shore Research Inc.

Sex: Female

Age: 18+

Code: NCT00703768

Recruiting

Albuvirtide in Combination With 3BNC117 in Patients With Multi-Drug Resistant (MDR) HIV-1 Infection

for
HIV/AIDS
Location: West Palm Beach FL, Hialeah FL, Orlando FL, Decatur GA,
Sponsor: Frontier Biotechnologies Inc.

Sex: All

Age: 18+

Code: NCT04560569

Phase 2, Recruiting

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for
mCRPC (Metastatic Castration-resistant Prostate Cancer),
Location: New York NY, Baltimore MD, Fairfax VA, Durham NC,
Sponsor: Pathos AI, Inc.

Sex: Male

Age: 18+

Code: NCT06785636

Phase 1, Phase 2, Recruiting

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

for
Relapsed or Refractory Acute Myeloid Leukemia (AML)
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18 - 70+

Code: NCT06660368

Phase 2, Recruiting

PhysioFlow to Detect Cardiotoxicity in Chemo

for
Chemotherapy, Cancer, Cardiotoxicity, Physioflow
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18+

Code: NCT02220569

Recruiting

Erectile Recovery After Robotic-Assisted Laparoscopic Prostatectomy

for
Erectile Dysfunction, Prostate Cancer
Location: San Antonio TX
Sponsor: Brooke Army Medical Center

Sex: Male

Age: 30 - 70+

Code: NCT03406169

Phase 3, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer