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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix

for
Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 0+

Code: NCT05046080

Recruiting

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

for
Liver Cancer, Rhabdomyosarcoma, Malignant Rhabdoid Tumor,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 1 - 21

Code: NCT04715191

Phase 1, Recruiting

Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer

for
Malignant Neoplasms of Respiratory and Intrathoracic Organs,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03114462

Phase 1, Recruiting

Effect of Needle Size in Diagnostic Yield of EBUS-TBNA in Sarcoidosis and Lymphoma

for
Sarcoidosis, Lymphoma, Adenopathy Hilar
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT03573362

Recruiting

An Efficacy and Safety Study to Assess [18F]-ML-10 in Detecting Response of Tumors to Chemotherapy and Radiation

for
Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms
Location: Boston MA, New York NY, Teaneck NJ, Pittsburgh, PA
Sponsor: Aposense Ltd.

Sex: All

Age: 18+

Code: NCT01260480

Phase 2, Recruiting

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A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC)

for
Biliary Cancer, Bile Duct Cancer, Cancer of the Bile Duct
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05849480

Phase 1, Phase 2, Recruiting

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

for
Prostate Cancer, Breast Cancer, Lung Cancer, Ovarian Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 3+

Code: NCT01441089

Recruiting

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

for
Follicular Lymphoma, Mantle Cell Lymphoma, Hairy Cell Leukemia,
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT06340737

Phase 1, Recruiting

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

for
Ovarian Cancer, Endometrial Cancer, Germ Cell Tumor,
Location: The Bronx NY, New York NY, Hackensack NJ,
Sponsor: Xencor, Inc.

Sex: All

Age: 15+

Code: NCT06276491

Phase 1, Recruiting

Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

for
Hyperandrogenism, Polycystic Ovary Syndrome, Puberty
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: Female

Age: 10 - 17

Code: NCT04723862

Early Phase 1, Recruiting

Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

for
Chordoma of Spine, Chordoma of Skull Base, Chordoma of Sacrum
Location: Philadelphia PA, Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT06463262

Recruiting

Safety and Efficacy of Talactoferrin in Addition to Standard Chemotherapy in Patients With Non-small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: Bronx NY, Durham NC, Chattanooga TN, Nashville TN,
Sponsor: Agennix

Sex: All

Age: 18+

Code: NCT00706862

Phase 3, Recruiting

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)

for
Relapsed/Refractory Systemic Light Chain Amyloidosis
Location: Boston MA, Buffalo NY, Columbus OH, Detroit MI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06292780

Phase 1, Phase 2, Recruiting

Revumenib in Combination With 7+3 + Midostaurin in AML

for
Acute Myeloid Leukemia, AML, Adult, AML With Gene Mutations,
Location: Boston MA, New Haven CT
Sponsor: Richard Stone, MD

Sex: All

Age: 18 - 70+

Code: NCT06313437

Phase 1, Recruiting

Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

for
Platinum-Resistant Fallopian Tube Carcinoma,
Location: Pittsburgh PA
Sponsor: Ronald Buckanovich

Sex: Female

Age: 18+

Code: NCT05538091

Phase 2, Recruiting

Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

for
Hormone Receptor-Positive Breast Cancer,
Location: Long Branch NJ, Elizabeth NJ, Newark NJ, Livingston NJ,
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT06518837

Phase 2, Recruiting

Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

for
Triple Negative Breast Cancer, Non Small Cell Lung Cancer,
Location: Hartford CT, Commack NY, Norwalk CT, Uniondale NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT03808337

Phase 2, Recruiting

Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe

for
Prostate Cancer
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 40 - 70+

Code: NCT05965180

Recruiting

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

for
Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12+

Code: NCT03589729

Phase 2, Recruiting

Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05424029

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer