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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Cisplatin, Metronomic Low-Dose Interferon Alfa, Gemcitabine, and Fever-Range Whole-Body Hyperthermia in Treating Patients With Inoperable or Metastatic Pancreatic Cancer

for
Pancreatic Cancer
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT00082862

Phase 2, Recruiting

A Study Comparing GLIADEL to Stereotactic Radiosurgery in Metastatic Brain Disease

for
Brain Tumor - Metastatic
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 18+

Code: NCT04222062

Phase 2, Recruiting

FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer

for
Breast Cancer
Location: Boston MA, Port Jefferson Station NY, Tampa FL,
Sponsor: Regor Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT05304962

Phase 1, Recruiting

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for
Leukemia, Juvenile Myelomonocytic, JMML, JCML,
Location: New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All

Age: 0 - 21

Code: NCT05849662

Phase 1, Phase 2, Recruiting

Blood Sample Collection and Health Information Collection From Patients With Invasive Breast Cancer and Their Brothers and Sisters

for
Breast Cancer
Location: Duarte CA
Sponsor: GenBasix Incorporated

Sex: All

Age: 18+

Code: NCT00445562

Recruiting

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Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

for
Recurrent Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04140487

Phase 1, Phase 2, Recruiting

Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma

for
High Grade Glioma
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 10 - 70+

Code: NCT05632562

Early Phase 1, Recruiting

High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer

for
Prostatic Cancer
Location: Omaha NE
Sponsor: University of Nebraska

Sex: Male

Age: 19+

Code: NCT05754580

Recruiting

Patients With Rectal Cancer: a "Wait-and-see" Approach

for
Colorectal Carcinoma
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18 - 70+

Code: NCT03001362

Recruiting

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

for
Relapsed/Refractory KMT2A-r Acute Leukemia,
Location: Boston MA, New York NY, Philadelphia PA, Toronto,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 21

Code: NCT06376162

Phase 1, Recruiting

A Study of Concurrent Stereotactic Body Radiotherapy With Opdualag in Metastatic Uveal Melanoma

for
Uveal Melanoma
Location: San Francisco CA
Sponsor: California Pacific Medical Center Research Institute

Sex: All

Age: 18+

Code: NCT05077280

Phase 2, Recruiting

XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Male

Age: 18+

Code: NCT06568562

Phase 2, Recruiting

Collection and Distribution of Biospecimens for Novel Research Uses

for
Cancer, Healthy, Gastrointestinal Complication,
Location: Huntsville AL
Sponsor: iSpecimen Inc

Sex: All

Age: 0 - 70+

Code: NCT03848962

Recruiting

Physical Activity and Community EmPOWERment Project

for
Intellectual Disability, Neurodevelopmental Disorders,
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18+

Code: NCT06740162

Recruiting

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

for
High Grade Glioma, CNS Tumor
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 3

Code: NCT06528691

Phase 2, Recruiting

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for
Chronic Pancreatitis, Exocrine Pancreas Carcinoma,
Location: Boston MA, Montreal, Philadelphia PA, Baltimore MD,
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0 - 17

Code: NCT06651580

Recruiting

A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors

for
Solid Tumor
Location: Providence RI, Philadelphia PA, Fairfax VA,
Sponsor: Chugai Pharmaceutical

Sex: All

Age: 18+

Code: NCT05907980

Phase 1, Recruiting

MRI Predictors of Response to Tumor Treating Fields

for
Glioblastoma Multiforme
Location: Brooklyn NY
Sponsor: New York Presbyterian Brooklyn Methodist Hospital

Sex: All

Age: 18+

Code: NCT03642080

Recruiting

Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue

for
Bladder Cancer, Urinary Tract Cancer, Urothelial Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT02379429

Recruiting

Tissue Collection Protocol for Gastroesophageal Cancers

for
Esophageal Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT02495337

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer